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Antagonistic coevolution between a bacterium and a bacteriophage
Open accessAbstract
Antagonistic coevolution between hosts and parasites is believed to play a pivotal role in host and parasite population dynamics, the evolutionary maintenance of sex and the evolution of parasite virulence. Furthermore, antagonistic coevolution is believed to be responsible for rapid differentiation of both hosts and parasites between geographically structured populations. Yet empirical evidence for host-parasite antagonistic coevolution, and its impact on between-population genetic divergence, is limited. Here we demonstrate a long-term arms race between the infectivity of a viral parasite (bacteriophage; phage) and the resistance of its bacterial host. Coevolution was largely driven by directional selection, with hosts becoming resistant to a wider range of parasite genotypes and parasites infective to a wider range of host genotypes. Coevolution followed divergent trajectories between replicate communities despite establishment with isogenic bacteria and phage, and resulted in bacteria adapted to their own, compared with other, phage populations.
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Cited by
The arms race between bacteria and their phage foes
Hampton, H. G., Watson, B. N. J., & Fineran, P. C. (2020) · Nature · doi:10.1038/s41586-019-1894-8 · Cited by 917
Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy
Oechslin, F. (2018) · Viruses · doi:10.3390/v10070351 · Cited by 594
Big questions, small worlds: microbial model systems in ecology
Jessup, C. M., Kassen, R., Forde, S. E., Kerr, B., Buckling, A., Rainey, P. B., & Bohannan, B. J. M. (2004) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2004.01.008 · Cited by 455
Self-citationCook, R., Hooton, S., Trivedi, U., King, L., Dodd, C. E. R., Hobman, J. L., Stekel, D. J., Jones, M. A., & Millard, A. D. (2021) · Microbiome · doi:10.1186/s40168-021-01010-3 · Cited by 319
Parent‐Offspring Conflict in the Evolution of Vertebrate Reproductive Mode
Crespi, B., & Semeniuk, C. (2004) · The American Naturalist · doi:10.1086/382734 · Cited by 278
Metadata
- Authors
- Buckling, A., & Rainey, P. B.
- Venue
- Proceedings of the Royal Society of London. Series B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2002-05-07
- Volume
- 269
- Issue
- 1494
- Pages
- 931-936
- ISSN
- 0080-4649 (ISSN-L)
- 0962-8452
- 1471-2954
- OpenAlex
- W2099670135
- Cited by
- 638
- References
- 0
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- green
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- Buckling, A., & Rainey, P. B. (2002). Antagonistic coevolution between a bacterium and a bacteriophage. Proceedings of the Royal Society of London. Series B: Biological Sciences. https://doi.org/10.1098/rspb.2001.1945
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