The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Structure and function of antifreeze proteins
Open accessAbstract
High–resolution three–dimensional structures are now available for four of seven non–homologous fish and insect antifreeze proteins (AFPs). For each of these structures, the ice–binding site of the AFP has been defined by site–directed mutagenesis, and ice etching has indicated that the ice surface is bound by the AFP. A comparison of these extremely diverse ice–binding proteins shows that they have the following attributes in common. The binding sites are relatively flat and engage a substantial proportion of the protein's surface area in ice binding. They are also somewhat hydrophobic—more so than that portion of the protein exposed to the solvent. Surface–surface complementarity appears to be the key to tight binding in which the contribution of hydrogen bonding seems to be secondary to van der Waals contacts.
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Cites
Adsorption inhibition as a mechanism of freezing resistance in polar fishes.
Raymond, J. A., & DeVries, A. L. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.6.2589 · Cited by 858
Freezing Resistance in Some Antarctic Fishes
DeVries, A. L., & Wohlschlag, D. E. (1969) · Science · doi:10.1126/science.163.3871.1073 · Cited by 691
Adsorption of alpha-helical antifreeze peptides on specific ice crystal surface planes
Knight, C. A., Cheng, C. C., & DeVries, A. L. (1991) · Biophysical Journal · doi:10.1016/s0006-3495(91)82234-2 · Cited by 517
Antifreeze and Ice Nucleator Proteins in Terrestrial Arthropods
Duman, J. G. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.327 · Cited by 513
Antifreeze Proteins of Teleost Fishes
Fletcher, G. L., Hew, C. L., & Davies, P. L. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.359 · Cited by 508
Self-citationMimicry of ice structure by surface hydroxyls and water of a β-helix antifreeze protein
Liou, Y.-C., Tocilj, A., Davies, P. L., & Jia, Z. (2000) · Nature · doi:10.1038/35018604 · Cited by 492
Self-citationβ-Helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect
Graether, S. P., Kuiper, M. J., Gagné, S. M., Walker, V. K., Jia, Z., Sykes, B. D., & Davies, P. L. (2000) · Nature · doi:10.1038/35018610 · Cited by 471
Self-citationChemical and Physical Properties of Freezing Point-depressing Glycoproteins from Antarctic Fishes
DeVries, A. L., Komatsu, S. K., & Feeney, R. E. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63073-x · Cited by 451
Ice-binding structure and mechanism of an antifreeze protein from winter flounder
Sicheri, F., & Yang, D. S. C. (1995) · Nature · doi:10.1038/375427a0 · Cited by 417
Antifreeze Proteins in Winter Rye Are Similar to Pathogenesis-Related Proteins
Hon, W. C., Griffith, M., Mlynarz, A., Kwok, Y., & Yang, D. (1995) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.3.879 · Cited by 339
Cited by
Bone recognition mechanism of porcine osteocalcin from crystal structure
Hoang, Q. Q., Sicheri, F., Howard, A. J., & Yang, D. S. C. (2003) · Nature · doi:10.1038/nature02079 · Cited by 554
Pentelute, B. L., Gates, Z. P., Dashnau, J. L., Vanderkooi, J. M., & Kent, S. B. H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja801352j · Cited by 77
De novo designed ice-binding proteins from twist-constrained helices
de Haas, R. J., Tas, R. P., van den Broek, D., Zheng, C., Nguyen, H., Kang, A., Bera, A. K., King, N. P., Voets, I. K., & de Vries, R. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2220380120 · Cited by 12
Inhibition of ice recrystallization with designed twistless helical repeat proteins
de Haas, R. J., Pyles, H., Huddy, E. B., van Ossenbruggen, J., Zheng, C., van den Broek, D., Giezen, S. N., Carr, A., Bera, A. K., Kang, A., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2514871122 · Cited by 6
Metadata
- Authors
- Davies, P. L., Baardsnes, J., Kuiper, M. J., & Walker, V. K.
- Venue
- Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2002-07-29
- Volume
- 357
- Issue
- 1423
- Pages
- 927-935
- ISSN
- 0962-8436 (ISSN-L)
- 1471-2970
- OpenAlex
- W2148378265
- Cited by
- 313
- References
- 32
- FWCI
- 2.38
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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