The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Genomic islands of divergence in hybridizing Heliconius butterflies identified by large-scale targeted sequencing
Open accessAbstract
Heliconius butterflies represent a recent radiation of species, in which wing pattern divergence has been implicated in speciation. Several loci that control wing pattern phenotypes have been mapped and two were identified through sequencing. These same gene regions play a role in adaptation across the whole Heliconius radiation. Previous studies of population genetic patterns at these regions have sequenced small amplicons. Here, we use targeted next-generation sequence capture to survey patterns of divergence across these entire regions in divergent geographical races and species of Heliconius . This technique was successful both within and between species for obtaining high coverage of almost all coding regions and sufficient coverage of non-coding regions to perform population genetic analyses. We find major peaks of elevated population differentiation between races across hybrid zones, which indicate regions under strong divergent selection. These ‘islands’ of divergence appear to be more extensive between closely related species, but there is less clear evidence for such islands between more distantly related species at two further points along the ‘speciation continuum’. We also sequence fosmid clones across these regions in different Heliconius melpomene races. We find no major structural rearrangements but many relatively large (greater than 1 kb) insertion/deletion events (including gain/loss of transposable elements) that are variable between races.
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Cites
The Sequence Alignment/Map format and SAMtools
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.
Tajima, F. (1989) · Genetics · doi:10.1093/genetics/123.3.585 · Cited by 13,941
Principles of Population Genetics.
Cormack, R. M., Hartl, D. L., & Clark, A. G. (1990) · Biometrics · doi:10.2307/2531471 · Cited by 5,242
Multiple sequence alignment with the Clustal series of programs
Chenna, R. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg500 · Cited by 4,875
ACT: the Artemis comparison tool
Carver, T. J., Rutherford, K. M., Berriman, M., Rajandream, M.-A., Barrell, B. G., & Parkhill, J. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti553 · Cited by 1,610
Population Genomics of Parallel Adaptation in Threespine Stickleback using Sequenced RAD Tags
Hohenlohe, P. A., Bassham, S., Etter, P. D., Stiffler, N., Johnson, E. A., & Cresko, W. A. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000862 · Cited by 1,395
Separating the wheat from the chaff: patterns of genetic differentiation in high gene flow species
Waples, R. S. (1998) · Journal of Heredity · doi:10.1093/jhered/89.5.438 · Cited by 1,292
The genic view of the process of speciation
Wu, C.-I. (2001) · Journal of Evolutionary Biology · doi:10.1046/j.1420-9101.2001.00335.x · Cited by 1,276
Cited by
Abbott, R., Albach, D., Ansell, S., Arntzen, J. W., Baird, S. J. E., Bierne, N., Boughman, J., Brelsford, A., Buerkle, C. A., Buggs, R., et al. (2013) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2012.02599.x · Cited by 2,194
Self-citationCruickshank, T. E., & Hahn, M. W. (2014) · Molecular Ecology · doi:10.1111/mec.12796 · Cited by 1,061
Genomics and the origin of species
Seehausen, O., Butlin, R. K., Keller, I., Wagner, C. E., Boughman, J. W., Hohenlohe, P. A., Peichel, C. L., Saetre, G.-P., Bank, C., Brännström, Å., et al. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3644 · Cited by 1,016
Self-citationThe genomics of speciation-with-gene-flow
Feder, J. L., Egan, S. P., & Nosil, P. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.03.009 · Cited by 832
Hybridization, Introgression, and the Nature of Species Boundaries
(2014) · Journal of Heredity · doi:10.1093/jhered/esu033 · Cited by 745
Metadata
- Authors
- Nadeau, N. J., Whibley, A., Jones, R. T., Davey, J. W., Dasmahapatra, K. K., Baxter, S. W., Quail, M. A., Joron, M., ffrench-Constant, R. H., Blaxter, M. L., Mallet, J., & Jiggins, C. D.
- Venue
- Philosophical Transactions of the Royal Society B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2012-02-05
- Volume
- 367
- Issue
- 1587
- Pages
- 343-353
- ISSN
- 0962-8436 (ISSN-L)
- 1471-2970
- OpenAlex
- W2142666504
- Cited by
- 313
- References
- 55
- FWCI
- 19.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Nadeau, N. J., Whibley, A., Jones, R. T., Davey, J. W., Dasmahapatra, K. K., Baxter, S. W., Quail, M. A., Joron, M., ffrench-Constant, R. H., Blaxter, M. L., Mallet, J., & Jiggins, C. D. (2012). Genomic islands of divergence in hybridizing Heliconius butterflies identified by large-scale targeted sequencing. Philosophical Transactions of the Royal Society B: Biological Sciences. https://doi.org/10.1098/rstb.2011.0198
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