The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Aspergillus flavus: human pathogen, allergen and mycotoxin producer
Open accessAbstract
Aspergillus infections have grown in importance in the last years. However, most of the studies have focused on Aspergillus fumigatus, the most prevalent species in the genus. In certain locales and hospitals, Aspergillus flavus is more common in air than A. fumigatus, for unclear reasons. After A. fumigatus, A. flavus is the second leading cause of invasive aspergillosis and it is the most common cause of superficial infection. Experimental invasive infections in mice show A. flavus to be 100-fold more virulent than A. fumigatus in terms of inoculum required. Particularly common clinical syndromes associated with A. flavus include chronic granulomatous sinusitis, keratitis, cutaneous aspergillosis, wound infections and osteomyelitis following trauma and inoculation. Outbreaks associated with A. flavus appear to be associated with single or closely related strains, in contrast to those associated with A. fumigatus. In addition, A. flavus produces aflatoxins, the most toxic and potent hepatocarcinogenic natural compounds ever characterized. Accurate species identification within Aspergillus flavus complex remains difficult due to overlapping morphological and biochemical characteristics, and much taxonomic and population genetics work is necessary to better understand the species and related species. The flavus complex currently includes 23 species or varieties, including two sexual species, Petromyces alliaceus and P. albertensis. The genome of the highly related Aspergillus oryzae is completed and available; that of A. flavus in the final stages of annotation. Our understanding of A. flavus lags far behind that of A. fumigatus. Studies of the genomics, taxonomy, population genetics, pathogenicity, allergenicity and antifungal susceptibility of A. flavus are all required.
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Cites
Raper, K. B., & Fennell, D. I. (1973) · Andalas University Repository (Andalas University) · Cited by 1,685
Denning, D. W. (1998) · Clinical Infectious Diseases · doi:10.1086/513943 · Cited by 1,492
Self-citationEpidemiology and Outcome of Mould Infections in Hematopoietic Stem Cell Transplant Recipients
Marr, K. A., Carter, R. A., Crippa, F., Wald, A., & Corey, L. (2002) · Clinical Infectious Diseases · doi:10.1086/339202 · Cited by 1,448
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
Galagan, J. E., Calvo, S. E., Cuomo, C., Ma, L.-J., Wortman, J. R., Batzoglou, S., Lee, S.-I., Baştürkmen, M., Spevak, C. C., Clutterbuck, J., et al. (2005) · Nature · doi:10.1038/nature04341 · Cited by 1,365
Self-citationGenome sequencing and analysis of Aspergillus oryzae
Machida, M., Asai, K., Sano, M., Tanaka, T., Kumagai, T., Terai, G., Kusumoto, K.-I., Arima, T., Akita, O., Kashiwagi, Y., et al. (2005) · Nature · doi:10.1038/nature04300 · Cited by 1,245
Self-citationBenjamin, C. R., Raper, K. B., & Fennell, D. I. (1966) · Mycologia · doi:10.2307/3756932 · Cited by 1,176
Encyclopedia of food microbiology
(2000) · Choice Reviews Online · doi:10.5860/choice.38-0033 · Cited by 927
Bruns, T. D., White, T. J., & Taylor, J. W. (1991) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.22.110191.002521 · Cited by 902
Maertens, J., Raad, I., Petrikkos, G., Boogaerts, M., Selleslag, D., Petersen, F. B., Sable, C. A., Kartsonis, N. A., Ngai, A., Taylor, A., et al. (2004) · Clinical Infectious Diseases · doi:10.1086/423381 · Cited by 658
Self-citationDenning, D. W., Riniotis, K., Dobrashian, R., & Sambatakou, H. (2003) · Clinical Infectious Diseases · doi:10.1086/376526 · Cited by 554
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Amaike, S., & Keller, N. P. (2011) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-072910-095221 · Cited by 668
Changing epidemiology of systemic fungal infections
Richardson, M., & Lass-Flörl, C. (2008) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2008.01978.x · Cited by 524
Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer
Coker, O. O., Nakatsu, G., Dai, R. Z., Wu, W. K. K., Wong, S. H., Ng, S. C., Chan, F. K. L., Sung, J. J. Y., & Yu, J. (2019) · Gut · doi:10.1136/gutjnl-2018-317178 · Cited by 511
Fungal allergy in asthma-state of the art and research needs
Denning, D. W., Pashley, C., Hartl, D., Wardlaw, A., Godet, C., Del Giacco, S., Delhaes, L., & Sergejeva, S. (2014) · Clinical and Translational Allergy · doi:10.1186/2045-7022-4-14 · Cited by 357
Self-citationPopulation-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study)
Alastruey-Izquierdo, A., Mellado, E., Peláez, T., Pemán, J., Zapico, S., Alvarez, M., Rodríguez-Tudela, J. L., Cuenca-Estrella, M., & FILPOP Study Group (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00383-13 · Cited by 276
Metadata
- Authors
- Hedayati, M. T., Pasqualotto, A. C., Warn, P. A., Bowyer, P., & Denning, D. W.
- Venue
- Microbiology
- Publisher
- Microbiology Society
- Published
- 2007-06-01
- Volume
- 153
- Issue
- 6
- Pages
- 1677-1692
- ISSN
- 1350-0872 (ISSN-L)
- 1465-2080
- OpenAlex
- W2160867136
- Cited by
- 964
- References
- 84
- FWCI
- 17.43
- Type
- journal article
- Language
- en
- Open access
- green
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