Recovery of trait heritability from whole genome sequence data

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Items 101–200 of 208

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15. Causal Inference Methods to Integrate Omics and Complex Traits
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17. Complex Phenotypes: Mechanisms Underlying Variation in Human Stature
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18. Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy
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19. From Genome-Wide to Environment-Wide: Capturing the Environome
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20. Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study)
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24. Genetic associations of in vivo pathology influence Alzheimer’s disease susceptibility
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27. Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes
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28. On the diagnostic and neurobiological origins of bipolar disorder
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30. Using DNA to predict behaviour problems from preschool to adulthood
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31. Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes
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32. Negative selection on complex traits limits genetic risk prediction accuracy between populations
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33. Genomic heritability and correlation between carcass traits in Japanese Black cattle evaluated under different ceilings of relatedness among individuals
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34. A Genetic Map of the Modern Urban Society of Amsterdam
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35. Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations
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36. A large-scale multi-ethnic genome-wide association study of coronary artery disease
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37. Estimation of Non-null SNP Effect Size Distributions Enables the Detection of Enriched Genes Underlying Complex Traits
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38. VIKING II, a Worldwide Observational Cohort of Volunteers with Northern Isles Ancestry
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39. Integrating DNA sequencing and transcriptomic data for association analyses of low-frequency variants and lipid traits
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40. The epigenome of twins as a perfect laboratory for studying behavioural traits
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41. Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
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42. Biobank-scale inference of ancestral recombination graphs enables genealogy-based mixed model association of complex traits
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43. Genetic architecture of four smoking behaviors using partitioned SNP heritability
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44. Contribution of de novo and inherited rare CNVs to very preterm birth
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45. Population genetic simulation study of power in association testing across genetic architectures and study designs
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46. Why most Principal Component Analyses (PCA) in population genetic studies are wrong
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47. SNP heritability: What are we estimating?
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48. Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses
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49. An integrative machine learning approach to discovering multi-level molecular mechanisms of obesity using data from monozygotic twin pairs
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50. Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)
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51. Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories
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52. Rare variants analyses suggest novel cleft genes in the African population
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54. Imputed Genomic Data Reveals a Moderate Effect of Low Frequency Variants to the Heritability of Complex Human Traits
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55. The temporal relationship between parental concern of overeating and childhood obesity considering genetic susceptibility: longitudinal results from the IDEFICS/I.Family study
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56. A bio-environmental perspective on Emirati female college students’ experiences in virtual learning communities of inquiry
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57. Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)
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58. Mapping heritability of obesity by brain cell types
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59. The Genome-Wide Study of Human Social Behavior and Its Application in Sociology
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60. Non-additive effects of schizophrenia risk genes reflect convergent downstream function
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62. Germline variants are associated with increased primary melanoma tumor thickness at diagnosis
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63. Initial Study of Human Genetic Contribution to COVID-19 Severity and Susceptibility
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64. Meta-analysis of Scandinavian Schizophrenia Exomes
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65. How Array Design affects SNP Ascertainment Bias
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66. Characterising the genetic basis of immune response variation to identify causal mechanisms underlying disease susceptibility
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67. Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
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68. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE
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69. Alu element in the RNA binding motif protein, X-linked 2 (RBMX2) gene found to be linked to bipolar disorder
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71. Sleep and lifestyle in young adult monozygotic twin pairs discordant for body mass index
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76. Genetic architecture of four smoking behaviors using partitioned h2SNP.
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77. Evolutionary history of disease‐susceptibility loci identified in longitudinal exome‐wide association studies
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81. Genetic and environmental correlations between complex phenotypes differ by race/ethnicity and sex
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83. Heteroscedastic regression modeling elucidates gene-by-environment interaction
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85. Development of Personality in Adulthood: A Behavioral Genetic Perspective
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86. Rare Variants Analyses Suggest Novel Cleft Genes in the African Population
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95. Short-term heritable variation overwhelms two hundred generations of mutational variance for metabolic traits in Caenorhabditis elegans
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96. Genome-wide association and multi-omic analyses reveal new mechanisms for Heart Failure
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