Xenotransplanted human cortical neurons reveal species-specific development and functional integration into mouse visual circuits
Linaro, Daniele, Vermaercke, Ben, Iwata, Ryohei, Ramaswamy, Arjun, Davis, Brittany A., Boubakar, Leila, Libé-Philippot, Baptiste, Bilheu, Angéline +5 more·2019·Neuron
DOI 10.1101/626218
Cited by (210)
Items 101–200 of 210
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- A neurorecording toolkit for longitudinal assessments of transplanted human cortical organoids in vivoKate E. Herrema, Elizabeth K. Kharitonova, Daria Bogatova, Madison N. Wilson, Emily A Martin, Clara Chung, Francesca Puppo, Shira Klorfeld-Auslender, Pierre O. Boucher, Li‐Huei Tsai et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- Old enough to be a model? On the role of maturity in stem cell-based models for neuropsychiatric disordersBingqing He, Erik Smedler · 2026 · Neuroscience Applied
- Basal progenitors as drivers of neocortical expansionSoraia Barão, Ulrich Müller · 2026 · Trends in Neurosciences
- Purinergic–cytokine signaling as a regulatory axis in neuroimmune developmentJean Bezerra Silva, Fernanda Tibolla Viero, Guilherme Shigueto Vilar Higa, Natalia Turrini, Lucas Bonfim Marques, Guilherme Oliveira Carlos, Ana Beatriz Santos Silva, Alexandre Hiroaki Kihara, Silvia Honda Takada, Luiz Roberto Britto et al. · 2026 · Neuropharmacology
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- In preprints: releasing the brakes on neuronal maturationTeresa Rayón, Jelle van den Ameele · 2022 · Development
- Scientific and ethical challenges of brain chimeras converge on an ‘enriched’ approachJ. Lomax Boyd · 2023 · Molecular Psychology Brain Behavior and Society
- Molecular mechanisms of the specialization of human synapses in the neocortexEirini Christopoulou, Cécile Charrier · 2024 · Current Opinion in Genetics & Development
- Protocol for single-molecule imaging of transcription and epigenetic factors in human neural stem cell-derived neuronsYuri Atsumi, Nobuhiko Yamamoto, Noriyuki Sugo · 2024 · STAR Protocols
- A Closer Look to the Evolution of Neurons in Humans and Apes Using Stem-Cell-Derived Model SystemsMaria Schörnig, Elena Taverna · 2021 · Frontiers in Cell and Developmental Biology
- Cerebral Organoids in Developmental NeuroscienceAndrea Forero, Silvia Cappello · 2022 · Springer eBooks
- Building functional circuits in multispecies brainsBenjamin T. Throesch, Muhammad Khadeesh bin Imtiaz, Rodrigo Muñoz-Castañeda, Masahiro Sakurai, Andrea L. Hartzell, Kiely N. James, Alberto R. Rodriguez, Greg Martin, Giordano Lippi, Sergey Kupriyanov et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Electrophysiology and Morphology of Human Cortical Supragranular Pyramidal Cells in a Wide Age RangePál Barzó, Ildikó Szöts, Martin Tóth, Éva Csajbók, Gábor Molnár, Gábor Tamás · 2024 · eLife
- Electrophysiology and Morphology of Human Cortical Supragranular Pyramidal Cells in a Wide Age RangePál Barzó, Ildikó Szöts, Martin Tóth, Éva Csajbók, Gábor Molnár, Gábor Tamás · 2025 · eLife
- Intravital Multimodal Imaging of Human Cortical Organoids for Chronic Stroke Treatment in MiceJinghui Wang, Guanda Qiao, Hong‐Lin Tan, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Mirosław Janowski, Tian-ming Fu B, Piotr Walczak, Yajie Liang · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- From injury to recovery: functional neuronal regeneration after traumatic brain injury in the telencephalon of the young adult killifishValerie Mariën, Caroline Zandecki, Jolien Van houcke, Anouk Maes, Rajagopal Ayana, Chris Van den Haute, Rik Gijsbers, Marialuisa Tognolina, Lut Arckens · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Building axons: from formation to functionFeline W Lindhout · 2021
- Human-mouse chimeric Fragile X syndrome model reveals FMR1-dependent neuronal phenotypesMarine Krzisch, Hao Wu, Bingbing Yuan, Troy W. Whitfield, X. Shawn Liu, Dongdong Fu, Carrie M. Garrett-Engele, Aaron N. Chang, Stephen T. Warren, Angela M. Cacace et al. · 2020 · Research Square
- Bibliographie2022
- Roads of growthRobbelien Kooistra · 2022
- Cerebral Organoids in Developmental NeuroscienceAndrea Forero, Silvia Cappello · 2022 · Springer eBooks
- Gene editing hPSCs for modeling neurological disordersAndrew J. Petersen · 2022 · Elsevier eBooks
- Functional Integration of 3D-Printed Cerebral Cortical Tissue into a Brain LesionYongcheng Jin, Ellina Mikhailova, Ming Lei, Sally A. Cowley, Tianyi Sun, Xingyun Yang, Yujia Zhang, Kaili Liu, Daniel Catarino, Luana Campos Soares et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- An in vivo platform for rebuilding functional neocortical tissueAlexandra Quezada, Claire Ward, Edward R. Bader, Pavlo Zolotavin, Esra Altun, Sarah Hong, Nathaniel J. Killian, Chong Xie, Renata Batista‐Brito, Jean M. Hébert · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Clinical and Molecular Overview of Cortical MalformationsVeronica M. Pravatà, Pierre Gressèns, S. andCappello · 2023 · Wiley eBooks
- Mechanisms guiding the slow pace of maturation in human neurons uncovered2024 · Nature
- Rev or restrain: Mechanisms of human-specific synaptic neotenyJenelle L. Wallace, Alex A. Pollen · 2024 · Neuron
- Machine Learning Resolves Functional Phenotypes and Therapeutic Responses in KCNQ2 Developmental Epileptic Encephalopathy iPSC ModelsDina Simkin, Syed M.A. Wafa, Mennat Gharib, Kelly A. Marshall, Yezi Yang, Linda C. Laux, Alfred L. George, Evangelos Kiskinis · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Human neurons undergo protracted functional maturation into adulthoodMatthijs B Verhoog, Roxanne M Hattingh, Pia Scharein, Tariro A Chatiza, Nawaal Samsodien, Yanelisa Pulani, Amalia Naita Awala, Jared Tavares, Eline Jasmijn Mertens, Christiaan P. J. de Kock et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- Exploring the singularity of human neurons: keep calm and carry onBaptiste Libé‐Philippot · 2025 · Frontiers in Synaptic Neuroscience
- Genomic basis of human-specific brain featuresFederica Mosti, Debra L. Silver · 2025 · Elsevier eBooks
- Long-lasting structural and functional maturation in transplanted human neurons reprogrammed from glial progenitor cellsEfraín Cepeda-Prado, Christina Anastasia Stamouli, Gianluigi Nocera, Constanza Aretio-Medina, Srisaiyini Kidnapillai, Andreas Bruzelius, Jessica Giacomoni, Janko Kajtez, Malin Parmar, Daniella Rylander Ottosson · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 1 of hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatumRoberta Schellino, Dario Besusso, Roberta Parolisi et al. · 2023 · Figshare
- Aβ plaques induce local pre-synaptic toxicity in human iPSC-derived neuron xenograftsJacqueline F. M. van Vierbergen, Carles Calatayud, Sriram Balusu, Nicolò Carrano, Nicolas Peredo, Katlijn Vints, Sandra F. Gallego, Katrien Horré, Bart De Strooper, Patrik Verstreken · 2026 · Stem Cell Reports
- Protocol for the generation and xenotransplantation of human induced pluripotent stem cell-derived neural progenitor cells into the mouse forebrainJulie J. McInvale, Chloe E. Ayers, Hemanta Sarmah, Kang Kim, Peter Reinhardt, Aayushi Mahajan, Nelson Humala, Barbara Corneo, Jared L. Sterneckert, Peter Canoll et al. · 2026 · STAR Protocols
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- Induced pluripotent stem cells in autism research: a review of current advances and future directionsArmin Ariaei, Arsh Haj Mohamad Ebrahim Ketabforoush, Sanaz Bordbar, Shirin Barati, Abolfazl Lotfi, Forough Azam Sayahpour, Faezeh Faghihi, Saeid Abediankenari · 2026 · Egyptian Journal of Medical Human Genetics
- Exploring the role of CHRFAM7A in the early stages of Alzheimer's disease : in vitro studies and development of a novel humanized mouse modelMaria Llach Pou · 2023 · theses.fr (ABES)
- Étude de la forme sporadique de la maladie d'Alzheimer à partir de modèles in vivo et de neurones humains reprogrammésCamille Thiberge · 2023 · theses.fr (ABES)