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Cited by 386

The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.

Cytosolic Ca2+ Buffers

Open access
Schwaller, B.·2010·Cold Spring Harbor Perspectives in Biology

Abstract

"Ca(2+) buffers," a class of cytosolic Ca(2+)-binding proteins, act as modulators of short-lived intracellular Ca(2+) signals; they affect both the temporal and spatial aspects of these transient increases in [Ca(2+)](i). Examples of Ca(2+) buffers include parvalbumins (α and β isoforms), calbindin-D9k, calbindin-D28k, and calretinin. Besides their proven Ca(2+) buffer function, some might additionally have Ca(2+) sensor functions. Ca(2+) buffers have to be viewed as one of the components implicated in the precise regulation of Ca(2+) signaling and Ca(2+) homeostasis. Each cell is equipped with proteins, including Ca(2+) channels, transporters, and pumps that, together with the Ca(2+) buffers, shape the intracellular Ca(2+) signals. All of these molecules are not only functionally coupled, but their expression is likely to be regulated in a Ca(2+)-dependent manner to maintain normal Ca(2+) signaling, even in the absence or malfunctioning of one of the components.

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Metadata

Authors
Schwaller, B.
Venue
Cold Spring Harbor Perspectives in Biology
Published
2010-10-13
Volume
2
Issue
11
Pages
a004051-a004051
ISSN
1943-0264 (ISSN-L)
OpenAlex
W2082855639
Cited by
386
References
114
Type
posted content
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Cytosolic Ca2+ Buffers. https://app.cochat.ai/papers/10.1101/cshperspect.a004051
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Schwaller, B. (2010). Cytosolic Ca2+ Buffers. Cold Spring Harbor Perspectives in Biology. https://doi.org/10.1101/cshperspect.a004051

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