HIV-1 Assembly, Budding, and Maturation
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Concomitant with or after budding, activation of the viral protease leads to cleavage of Gag at specific positions, inducing major structural rearrangements of the individual Gag domains and a dramatic change in virus morphology.
“Concomitant with or after budding, activation of the viral protease leads to cleavage of Gag at specific positions, inducing major structural rearrangements of the individual Gag domains and a dramatic change in virus morphology”
From Retrovirus maturation-an extraordinary structural transformation (2016) · cites this paper as [1]
Proteolytic cleavages catalysed by the viral protease lead to a spectacular structural rearrangement of the viral particle into a mature form that is competent to fuse with and infect a new cell.
“Subsequently, a series of proteolytic cleavages catalysed by the viral protease leads to a spectacular structural rearrangement of the viral particle into a mature form that is competent to fuse with and infect a new cell.”
From Retrovirus maturation-an extraordinary structural transformation (2016) · cites this paper as [1]
Activation of the protease, and cleavage of Gag into its individual Gag domains, leads to a major structural rearrangement that results in the formation of the mature capsid core encasing the condensed genome.
“Activation of the protease, and cleavage of Gag into its individual Gag domains leads to a major structural rearrangement that results in the formation of the mature capsid core encasing the condensed genome”
From Retrovirus maturation-an extraordinary structural transformation (2016) · cites this paper as [1]
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Cited by 101
- Authors
- Sundquist, W. I., & Krausslich, H.-G.
- ORCID
- Sundquist, W. I.
- Venue
- Cold Spring Harbor Perspectives in Medicine
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2012-08-01
- Volume
- 2
- Issue
- 8
- Pages
- a015420-a015420
- ISSN
- 2157-1422 (ISSN-L)
- PMC
- PMC3405834
- OpenAlex
- W4248471000
- Cited by
- 101
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 8 · 2020: 12 · 2019: 4 · 2018: 5 · 2017: 3 · 2016: 12 · 2015: 19 · 2014: 17 · 2013: 8 · 2012: 4
- Type
- posted content
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cold Spring Harbor Perspectives in Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and Retrovirus Studies
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Keywords
- HIV-1, viral assembly, viral budding, virus maturation, HIV-1 virions, HIV-1 life cycle
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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