Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease

Ma, Ming, Gallagher, Anna-Rachel, Somlo, Stefan·2017·Cold Spring Harbor Perspectives in Biology
DOI 10.1101/cshperspect.a028209

Cited by (132)

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  8. Valosin-containing protein in ciliary morphology: a novel target in ADPKD
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  9. Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease
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  10. Tubular cell plasticity—new hope for autosomal dominant polycystic kidney disease?
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  12. Aberrant Cellular Pathways in PKD
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  13. Ca 2+ -Dependent Regulation by the Cyclic AMP Pathway of Primary Cilium Length in LLC-PK1 Renal Epithelial Cells
    Noelia Scarinci, Paula L. Perez, María del Rocío Cantero, Horacio F. Cantiello · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  14. NBCn1 interacts with DYNLL1 and regulates ciliary length and SUFU localization to control Sonic hedgehog signaling
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  15. Hypertension in adult polycystic kidney disease: a narrative review
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  16. Reduction the Length of the Primary Cilia by 1-Indanone Suppressed Renal Cysts Development in ADPKD
    Xiaowei Li, Hongsheng Zhou, Zhiwei Qiu, Jinzhao He, Shuyuan Wang, Mengna Wu, Shuai Zhu, Yongpan An, Ang Ma, Min Li et al. · 2021 · SSRN Electronic Journal
  17. Faculty Opinions recommendation of Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
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  18. Developing the polycystic kidney disease interactome
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  19. Developing the polycystic kidney disease interactome
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  20. Aberrant centrosome biogenesis disrupts nephron progenitor cell renewal and fate resulting in fibrocystic kidney disease
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  21. BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss
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  22. Vascular Endothelial Cells and Atherosclerosis
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  23. Ciliary ARL13B drives renal cystogenesis via its GEF activity
    Robert E. Van Sciver, Avery Forster, Leslie M. Lewis, Tamara Caspary · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Translational readthrough therapy for ADPKD induces polycystin1 expression and partially rescues functional deficits in PKD1 mutant cells
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  25. Molecular pathology and cystogenic propensity of the ADPKD Taiwan founder variant
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  28. Primary cilium disassembly – from mechanisms to roles in physiology and disease
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  29. Metabolomics in renal cystic disease: links to mechanisms and identification of pathways for potential prediagnosis
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  30. Modulation of cyst growth in autosomal dominant polycystic kidney disease: mechanistic insights and therapeutic opportunities
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  31. Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies
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  32. Ciliary ARL13B Drives Cystogenesis in the Kidney by Its Guanine Nucleotide Exchange Factor Activity
    Robert E. Van Sciver, Avery Forster, Leslie M. Lewis, Tamara Caspary · 2026 · Journal of the American Society of Nephrology