Protocells and RNA Self-Replication

Joyce, Gerald F., Szostak, Jack W.·2018·Cold Spring Harbor Perspectives in Biology

Cited by (341)

Items 101–200 of 341

  1. Provenance of life: Chemical autonomous agents surviving through associative learning
    Stuart Bartlett, David Louapre · 2022 · Physical review. E
  2. Origins of life: first came evolutionary dynamics
    Charles D. Kocher, Ken A. Dill · 2023 · QRB Discovery
  3. Primordial mimicry induces morphological change in Escherichia coli
    Hui Lu, Honoka Aida, Masaomi Kurokawa, Feng Chen, Yang Xia, Jian Xu, Kai Li, Bei-Wen Ying, T. Yomo · 2022 · Communications Biology
  4. What can we learn from the construction of in vitro replication systems?
    Norikazu Ichihashi · 2019 · Annals of the New York Academy of Sciences
  5. Resolving the History of Life on Earth by Seeking Life As We Know It on Mars
    Christopher E. Carr · 2022 · Astrobiology
  6. Origin of Species before Origin of Life: The Role of Speciation in Chemical Evolution
    Tony Z. Jia, Melina Caudan, Irena Mamajanov · 2021 · Life
  7. Minimal RNA self-reproduction discovered from a random pool of oligomers
    Ryo Mizuuchi, Norikazu Ichihashi · 2023 · Chemical Science
  8. Vesicle formation of single-chain amphiphilic 4-dodecylbenzene sulfonic acid in water and micelle-to-vesicle transition induced by wet–dry cycles
    Meihua Gao, Na Du, Zhiyin Yao, Ying Li, Nan Chen, Wanguo Hou · 2021 · Soft Matter
  9. Optimization and Enhancement of the Peroxidase-like Activity of Hemin in Aqueous Solutions of Sodium Dodecylsulfate
    Nemanja Cvjetan, Lukas D. Schuler, Takashi Ishikawa, Peter Walde · 2023 · ACS Omega
  10. RNA ligase ribozymes with a small catalytic core
    Yoko Nomura, Yohei Yokobayashi · 2023 · Scientific Reports
  11. In search of the RNA world on Mars
    Angel Mojarro, Lin Jin, Jack W. Szostak, James W. Head III, Maria T. Zuber · 2021 · Geobiology
  12. A kinetic error filtering mechanism for enzyme-free copying of nucleic acid sequences
    Tobias Göppel, Benedikt Obermayer, Irene A. Chen, Ulrich Gerland · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life
    Zachary R. Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly Poppy Sinclair, Zoe R. Todd, Roy A. Black, Jack W. Szostak, David C. Catling · 2024 · PNAS Nexus
  14. Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world
    Suvam Roy, Supratim Sengupta · 2021 · Proceedings of the Royal Society B Biological Sciences
  15. Protocell Effects on RNA Folding, Function, and Evolution
    Ranajay Saha, J. Choi, Irene A. Chen · 2024 · Accounts of Chemical Research
  16. Differential stability and dynamics of DNA-based and RNA-based coacervates affect non-enzymatic RNA chemistry
    Karina K. Nakashima, Fatma Zohra Mihoubi, Jagandeep S. Saraya, Kieran O. Russell, Fidan Rahmatova, James D. Robinson, Maria Julia Maristany, Jan Huertas, Roger Rubio‐Sánchez, Rosana Collepardo‐Guevara et al. · 2025 · Nature Communications
  17. Charge Transport through Self‐Assembled Monolayers of Monoterpenoids
    Brian J. Cafferty, Yuan Li, Mostafa Baghbanzadeh, Dmitrij Rappoport, Mohammad Hassan Beyzavi, George M. Whitesides · 2019 · Angewandte Chemie International Edition
  18. Reconstitution of a Reversible Membrane Switch via Prenylation by One-Pot Cell-Free Expression
    Lei Kai, Sonal, Tamara Heermann, Petra Schwille · 2022 · ACS Synthetic Biology
  19. RNA‐Catalyzed RNA Ligation within Prebiotically Plausible Model Protocells**
    Saurja DasGupta, Stephanie J. Zhang, Merrick Pierson Smela, Jack W. Szostak · 2023 · Chemistry - A European Journal
  20. Advanced Praise for The Sentient Cell: The Cellular Foundations of Consciousness
    Arthur S. Reber, František Baluška, William B. Miller · 2023 · Oxford University Press eBooks
  21. Chemical thermodynamics for growing systems
    Yuki Sughiyama, Atsushi Kamimura, Dimitri Loutchko, Tetsuya J. Kobayashi · 2022 · Physical Review Research
  22. Hidden protein functions and what they may teach us
    Schwille, Petra, Frohn, Béla P. · 2022 · Trends in Cell Biology
  23. Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activation
    Saurja DasGupta, Zoe Weiss, Collin R. Nisler, Jack W. Szostak · 2024 · Proceedings of the National Academy of Sciences
  24. Perspective: Protocells and the Path to Minimal Life
    David W. Deamer · 2024 · Journal of Molecular Evolution
  25. pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water
    Long-Fei Wu, Ziwei Liu, John D. Sutherland · 2020 · Chemical Communications
  26. Pioneering role of RNA in the early evolution of life
    Israel Muñoz‐Velasco, Adrián Cruz-González, Ricardo Hernández-Morales, José Alberto Campillo-Balderas, Wolfgang Cottom-Salas, Rodrigo Jácome, Alberto Vázquez-Salazar · 2024 · Genetics and Molecular Biology
  27. Universal cold RNA phase transitions
    Paolo Rissone, Aurelien Severino, Isabel Pastor, Félix Ritort · 2024 · Proceedings of the National Academy of Sciences
  28. Nonenzymatic Template-Directed Primer Extension Using 2′-3′ Cyclic Nucleotides Under Wet-Dry Cycles
    Shikha Dagar, Susovan Sarkar, Sudha Rajamani · 2023 · Origins of Life and Evolution of Biospheres
  29. Intellectual frameworks to understand complex biochemical systems at the origin of life
    Burckhard Seelig, Irene A. Chen · 2025 · Nature Chemistry
  30. Fitness Landscapes and Evolution of Catalytic RNA
    Ranajay Saha, Alberto Vázquez-Salazar, Aditya Nandy, Irene A. Chen · 2024 · Annual Review of Biophysics
  31. A QUBO model of the RNA folding problem optimized by variational hybrid quantum annealing
    Tristan Zaborniak, Juan Giraldo, Hausi A. Müller, Hosna Jabbari, Ulrike Stege · 2022 · IEEE International Conference on Quantum Computing and Engineering (QCE)
  32. Flipons and the origin of the genetic code
    Alan G. Herbert · 2025 · Biology Letters
  33. Elucidating the Mechanism of Freeze‐Thaw Driven Content Mixing between Protocells
    Benedikt Peter, Petra Schwille · 2023 · ChemSystemsChem
  34. Effects of molecular crowding on a bimolecular group I ribozyme and its derivative that self-assembles to form ribozyme oligomers
    M. M. Rahman, Shigeyoshi Matsumura, Yoshiya Ikawa · 2018 · Biochemical and Biophysical Research Communications
  35. Prebiotic Membranes and Micelles Do Not Inhibit Peptide Formation During Dehydration
    Zachary R. Cohen, Brennan L. Kessenich, Avijit Hazra, Julia Nguyen, Richard S. Johnson, Michael J. MacCoss, Gojko Lalić, Roy A. Black, Sarah L. Keller · 2021 · ChemBioChem
  36. Photochemical synthesis of natural lipids in artificial and living cells
    Peng Ji, Alexander Harjung, Caroline H. Knittel, Alessandro Fracassi, Jiyue Chen, Roberto J. Brea, Neal K. Devaraj · 2025 · Nature Communications
  37. Vesicle formation of single-tailed amphiphilic alkyltrimethylammonium bromides in water induced by dehydration–rehydration
    Feixue Gong, Na Du, Wanguo Hou · 2022 · Soft Matter
  38. On the Evolutionary Development of Biological Organization from Complex Prebiotic Chemistry
    Kepa Ruiz‐Mirazo, Álvaro Moreno · 2023 · History, philosophy and theory of the life sciences
  39. The Informational Substrate of Chemical Evolution: Implications for Abiogenesis
    de la Escosura, Andrés · 2019 · Life
  40. A scaling law of multilevel evolution: how the balance between within- and among-collective evolution is determined
    Nobuto Takeuchi, Namiko Mitarai, Kunihiko Kaneko · 2021 · Genetics
  41. Addressing Evolutionary Questions with Synthetic Biology
    Florian Baier, Yolanda Schaerli · 2021 · Springer eBooks
  42. Alternative Pathways in Astrobiology: Reviewing and Synthesizing Contingency and Non-Biomolecular Origins of Terrestrial and Extraterrestrial Life
    Kuhan Chandru, Christian Potiszil, Tony Z. Jia · 2024 · Life
  43. Sequencing the origins of life
    Tony Z. Jia, Shota Nishikawa, Kosuke Fujishima · 2022 · BBA Advances
  44. Hypothesis for Molecular Evolution in the Pre‐Cellular Stage of the Origin of Life
    Yong Wang, Yiling Du · 2025 · Wiley Interdisciplinary Reviews - RNA
  45. Natural Selection beyond Life? A Workshop Report
    Sylvain Charlat, André Ariew, Pierrick Bourrat, María J. Ferreira Ruiz, Thomas Heams, Philippe Huneman, Sandeep Krishna, Michael Lachmann, Nicolas Lartillot, Louis d’Hendecourt et al. · 2021 · Life
  46. Biomolecular Condensates: From Bacterial Compartments to Incubator Spaces of Emergent Chemical Systems in Matter‐to‐Life Transitions
    Wade E. Schnorr, W. Seth Childers · 2024 · ChemSystemsChem
  47. Structural transition of replicable RNAs during in vitro evolution with Qβ replicase
    Ryo Mizuuchi, Kimihito Usui, Norikazu Ichihashi · 2019 · RNA
  48. Selectively advantageous instability in biotic and pre-biotic systems and implications for evolution and aging
    John Tower · 2024 · Frontiers in Aging
  49. Towards a Theory of Evolution as Multilevel Learning
    Vitaly Vanchurin, Yuri I. Wolf, Mikhail I. Katsnelson, Eugene V. Koonin · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  50. Origin & influence of autocatalytic reaction networks at the advent of the RNA world
    Stephen A. Zorc, Raktim N. Roy · 2024 · RNA Biology
  51. The prebiotic emergence of biological evolution
    Charles D. Kocher, Ken A. Dill · 2024 · Royal Society Open Science
  52. Living electronics in cellulose zoogleal mats
    Panagiotis Mougkogiannis, Anna E. Nikolaidou, Andrew Adamatzky · 2024 · Carbohydrate Polymer Technologies and Applications
  53. Scientific progress, normative discussions, and the pragmatic account of definitions of life
    Ludo L. J. Schoenmakers · 2023 · Synthese
  54. A stepwise emergence of evolution in the RNA world
    Philippe Nghe · 2025 · FEBS Letters
  55. The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity
    Suvam Roy, Supratim Sengupta · 2022 · Life
  56. RNA Replication and the RNA Polymerase Ribozyme
    Falk Wachowius, Philipp Holliger · 2021 · Wiley eBooks
  57. Kinetic Effects of β,γ-Modified Deoxynucleoside 5′-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA
    Noah A. Setterholm, Pouya Haratipour, B. A. Kashemirov, Charles E. McKenna, Gerald F. Joyce · 2020 · Biochemistry
  58. A compositional view comparing modern biological condensates and primitive phase‐separated compartments
    Selene M.C. Cannelli, R. S. Gupta, Tan Nguyen, Arunava Poddar, Srishti Sharma, Prachiti V. Vithole, Tony Z. Jia · 2023 · Peptide Science
  59. Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact?
    Armen Y. Mulkidjanian, Daria V. Dibrova, A. Yu. Bychkov · 2025 · Life
  60. Avoidance of error catastrophe via proofreading innate to template-directed polymerization
    Yoshiya J. Matsubara, Nobuto Takeuchi, Kunihiko Kaneko · 2023 · Physical Review Research
  61. Prognostic value of exosomal noncoding RNA in hepatocellular carcinoma: a meta-analysis
    Guilin Nie, Nan Lian, Dingzhong Peng · 2022 · Carcinogenesis
  62. Screening for Primordial RNA–Peptide Interactions Using High-Density Peptide Arrays
    Felix Jenne, Ivan Berezkin, Frank Tempel, Dimitry Schmidt, Roman Popov, Alexander Nesterov‐Mueller · 2023 · Life
  63. Recent progress in primitive polyester synthesis and membraneless microdroplet assembly
    Tony Z. Jia, Kuhan Chandru · 2023 · Biophysics and Physicobiology
  64. Efficient Assembly of Functional RNA by in Situ Phosphate Activation and Loop-Closing Ligation
    Jian Zhang, Aleksandar Radakovic, Filip Bošković, Harry R. M. Aitken, Long-Fei Wu, Jack W. Szostak · 2025 · Journal of the American Chemical Society
  65. Emergent and Convergent Features in the Laboratory Evolution of Polymerase Ribozymes
    David P. Horning · 2025 · Biochemistry
  66. A symbiotic origin of the ribosome?
    Michael Lynch, Andrew D. Ellington · 2026 · PNAS Nexus
  67. The Bootstrap Model of Prebiotic Networks of Proteins and Nucleic Acids
    Thomas Farquharson, Luca Agozzino, Ken A. Dill · 2022 · Life
  68. RNA life on the edge of catastrophe
    Irene A. Chen · 2024 · Proceedings of the National Academy of Sciences
  69. Polyethylene glycol molecular crowders enhance the catalytic ability of bimolecular bacterial RNase P ribozymes
    Md. Sohanur Rahman, Mst Ara Gulshan, Shigeyoshi Matsumura, Yoshiya Ikawa · 2020 · Nucleosides Nucleotides & Nucleic Acids
  70. The Biological Information Cycle
    Arthur S. Reber, František Baluška, William B. Miller · 2023 · Oxford University Press eBooks
  71. Natural Selection beyond Life? A Workshop Report
    2021
  72. An Executive Information System: Inherent Information and Functional Information
    2023
  73. The compact Casπ (Cas12l) ‘bracelet’ provides a unique structural platform for DNA manipulation
    Sun, Ao, Li, Cheng-Ping, Chen, Zhihang, Zhang, Shouyue, Li, Danyuan, Yang, Yun, Li, Long-Qi, Zhao, Yuqian, Wang, Kaichen, Li, Zhaofu et al. · 2022
  74. From the RNA-Peptide World: Prebiotic Reaction Conditions Compatible with Lipid Membranes for the Formation of Lipophilic Random Peptides in the Presence of Short Oligonucleotides, and More
    Augustin Lopez, A. Vauchez, Ghinwa Ajram, Anastasiia Shvetsova, Gabrielle Leveau, Michele Fiore, Peter Strazewski · 2024 · Life
  75. Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world
    2021
  76. Prebiotically Plausible ‘Patching’ of RNA Backbone Cleavage Through a 3′-5′ Pyrophosphate Linkage
    2019
  77. Prebiotic Vesicles Retain Solutes and Grow by Micelle Addition after Brief Cooling below the Membrane Melting Temperature
    Zachary R. Cohen, Zoe R. Todd, David C. Catling, Roy A. Black, Sarah L. Keller · 2022 · Langmuir
  78. Redox chemistry of early Earth and the origin of life
    Nurbubu T. Moldogazieva, Alexander A. Terentiev, Innokenty M. Mokhosoev, Dmitry V. Astakhov · 2026 · Communications Chemistry
  79. The secret life of RNA and lipids
    Tomasz Czerniak, James Sáenz · 2025 · RNA Biology
  80. Evidence for Phase Transitions in Replication Fidelity and Survival Probability at the Origin of Life
    Sy Garte · 2021 · BioCosmos
  81. From RNA to DNA: Emergence of reverse transcriptases from an ancestral RNA-dependent RNA polymerase
    Sávio Torres de Farías, Ana Karoline Nunes-Alves, Marco V. José · 2024 · Biosystems
  82. On the Origin of Information Dynamics in Early Life
    R. Gatenby, Jill A. Gallaher, Hemachander Subramanian, E. Hammarlund, C. Whelan · 2025 · Life
  83. Polymerization and replication of primordial RNA induced by clay-water interface dynamics
    Carla Alejandre, Adrián Aguirre‐Tamaral, Carlos Briones, Jacobo Aguirre · 2025 · Communications Chemistry
  84. Ancient Origin Properties of Natural Exosomes Contribute to Their Therapeutic Superiority Compared to Artificial Nanoparticles
    Philip W. Askenase · 2020 · Preprints.org
  85. Slow Freeze‐Thaw Cycles Enhanced Hybridization of Kilobase DNA with Long Complementary Sticky Ends
    N.N. Noda, Kohei Nomura, Naho Takahashi, Fumitaka Hashiya, Hiroshi Abe, Tomoaki Matsuura · 2024 · ChemSystemsChem
  86. Non-enzymatic primer extension with strand displacement
    2019
  87. Thermodynamic and stoichiometric laws ruling the fates of growing systems
    Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi · 2024 · Physical Review Research
  88. Charge Transport through Self‐Assembled Monolayers of Monoterpenoids
    Brian J. Cafferty, Yuan Li, Mostafa Baghbanzadeh, Dmitrij Rappoport, Mohammad Hassan Beyzavi, George M. Whitesides · 2019 · Angewandte Chemie
  89. Exploring the Influence of Intermolecular Interactions in Prebiotic Chemistry Using Laser Spectroscopy and Calculations
    Ander Camiruaga, Imanol Usabiaga, Camilla Calabrese, Iker Lamas, Francisco J. Basterretxea, José Andrés Fernández · 2021 · Chemistry - A European Journal
  90. Optimization and compartmentalization of a cell-free mixture of DNA amplification and protein translation
    Fuhai Han, Boying Xu, Nan Lu, Adriano Caliari, Hui Lu, Yang Xia, Masayuki Su’etsugu, Jian Chu Xu, Tetsuya Yomo · 2022 · Applied Microbiology and Biotechnology
  91. Selective amide bond formation in redox-active coacervate protocells
    2021
  92. Assembly of Replicating Protocells with Primitive Metabolism
    Caner Karabaşoğlu, Aysenur Saytas, Beril Akgol, Simay Mercimek, Ö. Duhan Toparlak · 2026 · Astrobiology
  93. Towards an RNA/Peptides World by the Direct RNA Template Mechanism: The Emergence of Membrane-Stabilizing Peptides in RNA-Based Protocells
    Yu Liang Shi, Chunwu Yu, Wentao Ma · 2023 · Life
  94. Did organs precede organisms in the origin of life?
    Fernando Baquero, Gabriel S. Bever, Vı́ctor de Lorenzo, Val F. Lanza, Carlos Briones · 2024 · microLife
  95. RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells
    2023
  96. How DNA and RNA subunits might have formed to make the first genetic alphabet
    Kristian Kyle Le Vay, Hannes Mutschler · 2020 · Nature
  97. Biomathematical model of prebiotic autocatalytic RNA networks shows birth of adaptive immunity from degenerating molecular parasite catalysts
    Magnus Pirovino, Christian Iseli, Joseph Alphonsus Curran, Bernard Conrad · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Investigating Prebiotic Protocells for an Understanding of the Origin of Life: A Comprehensive Perspective Combining the Chemical, Evolutionary and Historical Aspects
    Wentao Ma, Yuzhen Liang · 2022 · Royal Society of Chemistry eBooks
  99. Minimizing Product Inhibition in DNA Self‐Replication: Insights for Prebiotic Replication from the Role of the Enzyme in Lesion‐Induced DNA Amplification**
    Hansol Park, Shyam Parshotam, Sarah C. Hales, Anthony Mittermaier, Julianne M. Gibbs · 2023 · Chemistry - A European Journal
  100. Abiotic Synthesis and Role of Amphiphiles in the Encapsulation Process in Life’s Origin
    Augustin Lopez, Carolina Chieffo, Michele Fiore · 2021 · Advances in astrobiology and biogeophysics