Protocells and RNA Self-Replication
Joyce, Gerald F., Szostak, Jack W.·2018·Cold Spring Harbor Perspectives in Biology
Cited by (341)
Items 101–200 of 341
- Provenance of life: Chemical autonomous agents surviving through associative learningStuart Bartlett, David Louapre · 2022 · Physical review. E
- Origins of life: first came evolutionary dynamicsCharles D. Kocher, Ken A. Dill · 2023 · QRB Discovery
- Primordial mimicry induces morphological change in Escherichia coliHui Lu, Honoka Aida, Masaomi Kurokawa, Feng Chen, Yang Xia, Jian Xu, Kai Li, Bei-Wen Ying, T. Yomo · 2022 · Communications Biology
- What can we learn from the construction of in vitro replication systems?Norikazu Ichihashi · 2019 · Annals of the New York Academy of Sciences
- Resolving the History of Life on Earth by Seeking Life As We Know It on MarsChristopher E. Carr · 2022 · Astrobiology
- Origin of Species before Origin of Life: The Role of Speciation in Chemical EvolutionTony Z. Jia, Melina Caudan, Irena Mamajanov · 2021 · Life
- Minimal RNA self-reproduction discovered from a random pool of oligomersRyo Mizuuchi, Norikazu Ichihashi · 2023 · Chemical Science
- Vesicle formation of single-chain amphiphilic 4-dodecylbenzene sulfonic acid in water and micelle-to-vesicle transition induced by wet–dry cyclesMeihua Gao, Na Du, Zhiyin Yao, Ying Li, Nan Chen, Wanguo Hou · 2021 · Soft Matter
- Optimization and Enhancement of the Peroxidase-like Activity of Hemin in Aqueous Solutions of Sodium DodecylsulfateNemanja Cvjetan, Lukas D. Schuler, Takashi Ishikawa, Peter Walde · 2023 · ACS Omega
- RNA ligase ribozymes with a small catalytic coreYoko Nomura, Yohei Yokobayashi · 2023 · Scientific Reports
- In search of the RNA world on MarsAngel Mojarro, Lin Jin, Jack W. Szostak, James W. Head III, Maria T. Zuber · 2021 · Geobiology
- A kinetic error filtering mechanism for enzyme-free copying of nucleic acid sequencesTobias Göppel, Benedikt Obermayer, Irene A. Chen, Ulrich Gerland · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of lifeZachary R. Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly Poppy Sinclair, Zoe R. Todd, Roy A. Black, Jack W. Szostak, David C. Catling · 2024 · PNAS Nexus
- Evolution towards increasing complexity through functional diversification in a protocell model of the RNA worldSuvam Roy, Supratim Sengupta · 2021 · Proceedings of the Royal Society B Biological Sciences
- Protocell Effects on RNA Folding, Function, and EvolutionRanajay Saha, J. Choi, Irene A. Chen · 2024 · Accounts of Chemical Research
- Differential stability and dynamics of DNA-based and RNA-based coacervates affect non-enzymatic RNA chemistryKarina K. Nakashima, Fatma Zohra Mihoubi, Jagandeep S. Saraya, Kieran O. Russell, Fidan Rahmatova, James D. Robinson, Maria Julia Maristany, Jan Huertas, Roger Rubio‐Sánchez, Rosana Collepardo‐Guevara et al. · 2025 · Nature Communications
- Charge Transport through Self‐Assembled Monolayers of MonoterpenoidsBrian J. Cafferty, Yuan Li, Mostafa Baghbanzadeh, Dmitrij Rappoport, Mohammad Hassan Beyzavi, George M. Whitesides · 2019 · Angewandte Chemie International Edition
- Reconstitution of a Reversible Membrane Switch via Prenylation by One-Pot Cell-Free ExpressionLei Kai, Sonal, Tamara Heermann, Petra Schwille · 2022 · ACS Synthetic Biology
- RNA‐Catalyzed RNA Ligation within Prebiotically Plausible Model Protocells**Saurja DasGupta, Stephanie J. Zhang, Merrick Pierson Smela, Jack W. Szostak · 2023 · Chemistry - A European Journal
- Advanced Praise for The Sentient Cell: The Cellular Foundations of ConsciousnessArthur S. Reber, František Baluška, William B. Miller · 2023 · Oxford University Press eBooks
- Chemical thermodynamics for growing systemsYuki Sughiyama, Atsushi Kamimura, Dimitri Loutchko, Tetsuya J. Kobayashi · 2022 · Physical Review Research
- Hidden protein functions and what they may teach usSchwille, Petra, Frohn, Béla P. · 2022 · Trends in Cell Biology
- Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activationSaurja DasGupta, Zoe Weiss, Collin R. Nisler, Jack W. Szostak · 2024 · Proceedings of the National Academy of Sciences
- Perspective: Protocells and the Path to Minimal LifeDavid W. Deamer · 2024 · Journal of Molecular Evolution
- pH-Dependent peptide bond formation by the selective coupling of α-amino acids in waterLong-Fei Wu, Ziwei Liu, John D. Sutherland · 2020 · Chemical Communications
- Pioneering role of RNA in the early evolution of lifeIsrael Muñoz‐Velasco, Adrián Cruz-González, Ricardo Hernández-Morales, José Alberto Campillo-Balderas, Wolfgang Cottom-Salas, Rodrigo Jácome, Alberto Vázquez-Salazar · 2024 · Genetics and Molecular Biology
- Universal cold RNA phase transitionsPaolo Rissone, Aurelien Severino, Isabel Pastor, Félix Ritort · 2024 · Proceedings of the National Academy of Sciences
- Nonenzymatic Template-Directed Primer Extension Using 2′-3′ Cyclic Nucleotides Under Wet-Dry CyclesShikha Dagar, Susovan Sarkar, Sudha Rajamani · 2023 · Origins of Life and Evolution of Biospheres
- Intellectual frameworks to understand complex biochemical systems at the origin of lifeBurckhard Seelig, Irene A. Chen · 2025 · Nature Chemistry
- Fitness Landscapes and Evolution of Catalytic RNARanajay Saha, Alberto Vázquez-Salazar, Aditya Nandy, Irene A. Chen · 2024 · Annual Review of Biophysics
- A QUBO model of the RNA folding problem optimized by variational hybrid quantum annealingTristan Zaborniak, Juan Giraldo, Hausi A. Müller, Hosna Jabbari, Ulrike Stege · 2022 · IEEE International Conference on Quantum Computing and Engineering (QCE)
- Flipons and the origin of the genetic codeAlan G. Herbert · 2025 · Biology Letters
- Elucidating the Mechanism of Freeze‐Thaw Driven Content Mixing between ProtocellsBenedikt Peter, Petra Schwille · 2023 · ChemSystemsChem
- Effects of molecular crowding on a bimolecular group I ribozyme and its derivative that self-assembles to form ribozyme oligomersM. M. Rahman, Shigeyoshi Matsumura, Yoshiya Ikawa · 2018 · Biochemical and Biophysical Research Communications
- Prebiotic Membranes and Micelles Do Not Inhibit Peptide Formation During DehydrationZachary R. Cohen, Brennan L. Kessenich, Avijit Hazra, Julia Nguyen, Richard S. Johnson, Michael J. MacCoss, Gojko Lalić, Roy A. Black, Sarah L. Keller · 2021 · ChemBioChem
- Photochemical synthesis of natural lipids in artificial and living cellsPeng Ji, Alexander Harjung, Caroline H. Knittel, Alessandro Fracassi, Jiyue Chen, Roberto J. Brea, Neal K. Devaraj · 2025 · Nature Communications
- Vesicle formation of single-tailed amphiphilic alkyltrimethylammonium bromides in water induced by dehydration–rehydrationFeixue Gong, Na Du, Wanguo Hou · 2022 · Soft Matter
- On the Evolutionary Development of Biological Organization from Complex Prebiotic ChemistryKepa Ruiz‐Mirazo, Álvaro Moreno · 2023 · History, philosophy and theory of the life sciences
- The Informational Substrate of Chemical Evolution: Implications for Abiogenesisde la Escosura, Andrés · 2019 · Life
- A scaling law of multilevel evolution: how the balance between within- and among-collective evolution is determinedNobuto Takeuchi, Namiko Mitarai, Kunihiko Kaneko · 2021 · Genetics
- Addressing Evolutionary Questions with Synthetic BiologyFlorian Baier, Yolanda Schaerli · 2021 · Springer eBooks
- Alternative Pathways in Astrobiology: Reviewing and Synthesizing Contingency and Non-Biomolecular Origins of Terrestrial and Extraterrestrial LifeKuhan Chandru, Christian Potiszil, Tony Z. Jia · 2024 · Life
- Sequencing the origins of lifeTony Z. Jia, Shota Nishikawa, Kosuke Fujishima · 2022 · BBA Advances
- Hypothesis for Molecular Evolution in the Pre‐Cellular Stage of the Origin of LifeYong Wang, Yiling Du · 2025 · Wiley Interdisciplinary Reviews - RNA
- Natural Selection beyond Life? A Workshop ReportSylvain Charlat, André Ariew, Pierrick Bourrat, María J. Ferreira Ruiz, Thomas Heams, Philippe Huneman, Sandeep Krishna, Michael Lachmann, Nicolas Lartillot, Louis d’Hendecourt et al. · 2021 · Life
- Biomolecular Condensates: From Bacterial Compartments to Incubator Spaces of Emergent Chemical Systems in Matter‐to‐Life TransitionsWade E. Schnorr, W. Seth Childers · 2024 · ChemSystemsChem
- Structural transition of replicable RNAs during in vitro evolution with Qβ replicaseRyo Mizuuchi, Kimihito Usui, Norikazu Ichihashi · 2019 · RNA
- Selectively advantageous instability in biotic and pre-biotic systems and implications for evolution and agingJohn Tower · 2024 · Frontiers in Aging
- Towards a Theory of Evolution as Multilevel LearningVitaly Vanchurin, Yuri I. Wolf, Mikhail I. Katsnelson, Eugene V. Koonin · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Origin & influence of autocatalytic reaction networks at the advent of the RNA worldStephen A. Zorc, Raktim N. Roy · 2024 · RNA Biology
- The prebiotic emergence of biological evolutionCharles D. Kocher, Ken A. Dill · 2024 · Royal Society Open Science
- Living electronics in cellulose zoogleal matsPanagiotis Mougkogiannis, Anna E. Nikolaidou, Andrew Adamatzky · 2024 · Carbohydrate Polymer Technologies and Applications
- Scientific progress, normative discussions, and the pragmatic account of definitions of lifeLudo L. J. Schoenmakers · 2023 · Synthese
- A stepwise emergence of evolution in the RNA worldPhilippe Nghe · 2025 · FEBS Letters
- The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing ComplexitySuvam Roy, Supratim Sengupta · 2022 · Life
- RNA Replication and the RNA Polymerase RibozymeFalk Wachowius, Philipp Holliger · 2021 · Wiley eBooks
- Kinetic Effects of β,γ-Modified Deoxynucleoside 5′-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNANoah A. Setterholm, Pouya Haratipour, B. A. Kashemirov, Charles E. McKenna, Gerald F. Joyce · 2020 · Biochemistry
- A compositional view comparing modern biological condensates and primitive phase‐separated compartmentsSelene M.C. Cannelli, R. S. Gupta, Tan Nguyen, Arunava Poddar, Srishti Sharma, Prachiti V. Vithole, Tony Z. Jia · 2023 · Peptide Science
- Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact?Armen Y. Mulkidjanian, Daria V. Dibrova, A. Yu. Bychkov · 2025 · Life
- Avoidance of error catastrophe via proofreading innate to template-directed polymerizationYoshiya J. Matsubara, Nobuto Takeuchi, Kunihiko Kaneko · 2023 · Physical Review Research
- Prognostic value of exosomal noncoding RNA in hepatocellular carcinoma: a meta-analysisGuilin Nie, Nan Lian, Dingzhong Peng · 2022 · Carcinogenesis
- Screening for Primordial RNA–Peptide Interactions Using High-Density Peptide ArraysFelix Jenne, Ivan Berezkin, Frank Tempel, Dimitry Schmidt, Roman Popov, Alexander Nesterov‐Mueller · 2023 · Life
- Recent progress in primitive polyester synthesis and membraneless microdroplet assemblyTony Z. Jia, Kuhan Chandru · 2023 · Biophysics and Physicobiology
- Efficient Assembly of Functional RNA by in Situ Phosphate Activation and Loop-Closing LigationJian Zhang, Aleksandar Radakovic, Filip Bošković, Harry R. M. Aitken, Long-Fei Wu, Jack W. Szostak · 2025 · Journal of the American Chemical Society
- Emergent and Convergent Features in the Laboratory Evolution of Polymerase RibozymesDavid P. Horning · 2025 · Biochemistry
- A symbiotic origin of the ribosome?Michael Lynch, Andrew D. Ellington · 2026 · PNAS Nexus
- The Bootstrap Model of Prebiotic Networks of Proteins and Nucleic AcidsThomas Farquharson, Luca Agozzino, Ken A. Dill · 2022 · Life
- RNA life on the edge of catastropheIrene A. Chen · 2024 · Proceedings of the National Academy of Sciences
- Polyethylene glycol molecular crowders enhance the catalytic ability of bimolecular bacterial RNase P ribozymesMd. Sohanur Rahman, Mst Ara Gulshan, Shigeyoshi Matsumura, Yoshiya Ikawa · 2020 · Nucleosides Nucleotides & Nucleic Acids
- The Biological Information CycleArthur S. Reber, František Baluška, William B. Miller · 2023 · Oxford University Press eBooks
- Natural Selection beyond Life? A Workshop Report2021
- An Executive Information System: Inherent Information and Functional Information2023
- The compact Casπ (Cas12l) ‘bracelet’ provides a unique structural platform for DNA manipulationSun, Ao, Li, Cheng-Ping, Chen, Zhihang, Zhang, Shouyue, Li, Danyuan, Yang, Yun, Li, Long-Qi, Zhao, Yuqian, Wang, Kaichen, Li, Zhaofu et al. · 2022
- From the RNA-Peptide World: Prebiotic Reaction Conditions Compatible with Lipid Membranes for the Formation of Lipophilic Random Peptides in the Presence of Short Oligonucleotides, and MoreAugustin Lopez, A. Vauchez, Ghinwa Ajram, Anastasiia Shvetsova, Gabrielle Leveau, Michele Fiore, Peter Strazewski · 2024 · Life
- Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world2021
- Prebiotically Plausible ‘Patching’ of RNA Backbone Cleavage Through a 3′-5′ Pyrophosphate Linkage2019
- Prebiotic Vesicles Retain Solutes and Grow by Micelle Addition after Brief Cooling below the Membrane Melting TemperatureZachary R. Cohen, Zoe R. Todd, David C. Catling, Roy A. Black, Sarah L. Keller · 2022 · Langmuir
- Redox chemistry of early Earth and the origin of lifeNurbubu T. Moldogazieva, Alexander A. Terentiev, Innokenty M. Mokhosoev, Dmitry V. Astakhov · 2026 · Communications Chemistry
- The secret life of RNA and lipidsTomasz Czerniak, James Sáenz · 2025 · RNA Biology
- Evidence for Phase Transitions in Replication Fidelity and Survival Probability at the Origin of LifeSy Garte · 2021 · BioCosmos
- From RNA to DNA: Emergence of reverse transcriptases from an ancestral RNA-dependent RNA polymeraseSávio Torres de Farías, Ana Karoline Nunes-Alves, Marco V. José · 2024 · Biosystems
- On the Origin of Information Dynamics in Early LifeR. Gatenby, Jill A. Gallaher, Hemachander Subramanian, E. Hammarlund, C. Whelan · 2025 · Life
- Polymerization and replication of primordial RNA induced by clay-water interface dynamicsCarla Alejandre, Adrián Aguirre‐Tamaral, Carlos Briones, Jacobo Aguirre · 2025 · Communications Chemistry
- Ancient Origin Properties of Natural Exosomes Contribute to Their Therapeutic Superiority Compared to Artificial NanoparticlesPhilip W. Askenase · 2020 · Preprints.org
- Slow Freeze‐Thaw Cycles Enhanced Hybridization of Kilobase DNA with Long Complementary Sticky EndsN.N. Noda, Kohei Nomura, Naho Takahashi, Fumitaka Hashiya, Hiroshi Abe, Tomoaki Matsuura · 2024 · ChemSystemsChem
- Non-enzymatic primer extension with strand displacement2019
- Thermodynamic and stoichiometric laws ruling the fates of growing systemsAtsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi · 2024 · Physical Review Research
- Charge Transport through Self‐Assembled Monolayers of MonoterpenoidsBrian J. Cafferty, Yuan Li, Mostafa Baghbanzadeh, Dmitrij Rappoport, Mohammad Hassan Beyzavi, George M. Whitesides · 2019 · Angewandte Chemie
- Exploring the Influence of Intermolecular Interactions in Prebiotic Chemistry Using Laser Spectroscopy and CalculationsAnder Camiruaga, Imanol Usabiaga, Camilla Calabrese, Iker Lamas, Francisco J. Basterretxea, José Andrés Fernández · 2021 · Chemistry - A European Journal
- Optimization and compartmentalization of a cell-free mixture of DNA amplification and protein translationFuhai Han, Boying Xu, Nan Lu, Adriano Caliari, Hui Lu, Yang Xia, Masayuki Su’etsugu, Jian Chu Xu, Tetsuya Yomo · 2022 · Applied Microbiology and Biotechnology
- Selective amide bond formation in redox-active coacervate protocells2021
- Assembly of Replicating Protocells with Primitive MetabolismCaner Karabaşoğlu, Aysenur Saytas, Beril Akgol, Simay Mercimek, Ö. Duhan Toparlak · 2026 · Astrobiology
- Towards an RNA/Peptides World by the Direct RNA Template Mechanism: The Emergence of Membrane-Stabilizing Peptides in RNA-Based ProtocellsYu Liang Shi, Chunwu Yu, Wentao Ma · 2023 · Life
- Did organs precede organisms in the origin of life?Fernando Baquero, Gabriel S. Bever, Vı́ctor de Lorenzo, Val F. Lanza, Carlos Briones · 2024 · microLife
- RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells2023
- How DNA and RNA subunits might have formed to make the first genetic alphabetKristian Kyle Le Vay, Hannes Mutschler · 2020 · Nature
- Biomathematical model of prebiotic autocatalytic RNA networks shows birth of adaptive immunity from degenerating molecular parasite catalystsMagnus Pirovino, Christian Iseli, Joseph Alphonsus Curran, Bernard Conrad · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Investigating Prebiotic Protocells for an Understanding of the Origin of Life: A Comprehensive Perspective Combining the Chemical, Evolutionary and Historical AspectsWentao Ma, Yuzhen Liang · 2022 · Royal Society of Chemistry eBooks
- Minimizing Product Inhibition in DNA Self‐Replication: Insights for Prebiotic Replication from the Role of the Enzyme in Lesion‐Induced DNA Amplification**Hansol Park, Shyam Parshotam, Sarah C. Hales, Anthony Mittermaier, Julianne M. Gibbs · 2023 · Chemistry - A European Journal
- Abiotic Synthesis and Role of Amphiphiles in the Encapsulation Process in Life’s OriginAugustin Lopez, Carolina Chieffo, Michele Fiore · 2021 · Advances in astrobiology and biogeophysics