Genes of the Drosophila maternal dorsal group control the specific expression of the zygotic gene twist in presumptive mesodermal cells
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High levels of nuclear Dorsal present in ventral regions activate genes such as twist and snail, which are required for specification of the mesoderm.
“High levels of nuclear Dorsal present in ventral regions activate genes such as twist (twi) and snail (sna), which are required for specification of the mesoderm”
From Graded dorsal and differential gene regulation in the Drosophila embryo. (2009) · cites this paper as Thisse et al. 1987
The Discussion reports that dorsal (dl) activity is required for twist expression in presumptive mesodermal cells, and the introductory passage says twist and snail are involved in dorsoventral development. The paper does not establish that high levels of nuclear Dorsal in ventral regions activate both genes; it tests twist expression, not snail activation. Page numbers are not available in our copy. (LLM, conf=0.88)
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Research works printed but not linked: 2
- Anderson, K. and C. Nüsslein-Volhard. 1984a. Genetic analysis of dorso-ventral embryonic pattern in Drosophila. In Primers in developmental biology (ed. G. Malacinski and S. Bryant), pp. 269–289. Macmillan, New York.
- Campos-Ortega, J.A. and V. Hartenstein. 1985. The embryonic development of D. melanogaster. Springer-Verlag, BerlinHeidelberg.
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Graded dorsal and differential gene regulation in the Drosophila embryo.
Reeves, G. T., & Stathopoulos, A. (2009) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000836 · Cited by 119 · see citing works
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1987-09
- Volume
- 1
- Issue
- 7
- Pages
- 709-715
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W4236940297
- Cited by
- 94
- References
- 0
- Citations by year
- 2017: 1 · 2016: 2
- Type
- posted content
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Genes & Development (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Keywords
- twist gene, mesoderm differentiation, dorsal-ventral axis, zygotic gene expression, maternal-to-zygotic transition, embryonic patterning, hybrid embryos, Drosophila embryogenesis
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