Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways.

Cited by (300)

Items 201–300 of 300

1. A Dbf4 Mutant Contributes to Bypassing the Rad53-mediated Block of Origins of Replication in Response to Genotoxic Stress
   Alba Duch, Gloria Palou, Zophonías Oddur Jónsson, Roger Palou, Enrique Calvo, James Akira Wohlschlegel, David G. Quintana · 2010 · Journal of Biological Chemistry
2. Novel Role for Checkpoint Rad53 Protein Kinase in the Initiation of Chromosomal DNA Replication inSaccharomyces cerevisiae
   Paul R. Dohrmann, Robert A. Sclafani · 2006 · Genetics
3. ATP-Dependent Chromatin Remodeling Factors Tune S Phase Checkpoint Activity
   Tracey J. Au, Jairo Rodríguez, Jack A Vincent, Toshio Tsukiyama · 2011 · Molecular and Cellular Biology
4. Cotransport of the Heterodimeric Small Subunit of the Saccharomyces cerevisiae Ribonucleotide Reductase Between the Nucleus and the Cytoplasm
   Xiuxiang An, Zhen Zhang, Kui Yang, Mingxia Huang · 2006 · Genetics
5. Role of the N-terminal Forkhead-associated Domain in the Cell Cycle Checkpoint Function of the Rad53 Kinase
   Brietta L. Pike, Andrew Hammet, Jörg Heierhorst · 2001 · Journal of Biological Chemistry
6. Increased chromosomal mobility after DNA damage is controlled by interactions between the recombination machinery and the checkpoint
   Michael J. Smith, Eric Edward Bryant, Rodney J. Rothstein · 2018 · Genes & Development
7. Precocious S-Phase Entry in Budding Yeast Prolongs Replicative State and Increases Dependence Upon Rad53 for Viability
   Julia M. Sidorova, Linda L. Breeden · 2002 · Genetics
8. ATR signaling in mammalian meiosis: From upstream scaffolds to downstream signaling
   Catalina Pereira, Marcus Bustamante Smolka, Robert S. Weiss, Miguel A. Brieño‐Enríquez · 2020 · Environmental and Molecular Mutagenesis
9. Evidence of Meiotic Crossover Control in Saccharomyces cerevisiae Through Mec1-Mediated Phosphorylation of Replication Protein A
   Amy J. Bartrand, Dagmawi Iyasu, Suzanne M. Marinco, George S. Brush · 2005 · Genetics
10. A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae
    Ryan Janke, Kristina Herzberg, Michael L. Rolfsmeier, Jordan S Mar, Vladimir I. Bashkirov, Edwin Haghnazari, Greg T. Cantin, John R. Yates, Wolf‐Dietrich Heyer · 2010 · Nucleic Acids Research
11. Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage
    Violeta Cordón-Preciado, Sandra Ufano, Avelino Bueno · 2006 · Nucleic Acids Research
12. Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase
    Carolyn M. Jablonowski, José Renato Rosa Cussiol, Susannah Oberly, Askar Yimit, Attila Balint, Taehyung P. Kim, Zhaolei Zhang, Grant W. Brown, Marcus Bustamante Smolka · 2015 · Genetics
13. A Ddc2-Rad53 Fusion Protein Can Bypass the Requirements forRAD9andMRC1in Rad53 Activation
    Soo-Jung Lee, Jimmy Duong, David F. Stern · 2004 · Molecular Biology of the Cell
14. SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome
    Craig B. Bennett, Joyce R. Snipe, James W. Westmoreland, Michael A. Resnick · 2001 · Molecular and Cellular Biology
15. Interaction Between the MEC1-Dependent DNA Synthesis Checkpoint and G1 Cyclin Function in Saccharomyces cerevisiae
    Elizabeth A. Vallen, Frederick R. Cross · 1999 · Genetics
16. The DNA Damage Checkpoint and Human Cancer
    Linda Brooke Schultz, Nabil H. Chehab, Asra Malikzay, Richard A. DiTullio, Elena S. Stavridi, Thanos D. Halazonetis · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
17. Multiple Functions of the S-Phase Checkpoint Mediator
    Katsunori Tanaka · 2010 · Bioscience Biotechnology and Biochemistry
18. Telomere Structure, Replication and Length Maintenance
    Kalappa Muniyappa, K. Mary Kironmai · 1998 · Critical Reviews in Biochemistry and Molecular Biology
19. Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair
    Michael Tsabar, David P. Waterman, Fiona Aguilar, Lizabeth Katsnelson, Vinay V. Eapen, Gönen Memişoğlu, James E. Haber · 2016 · Genes & Development
20. The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1
    Jessica P. Lao, Katie Ulrich, Jeffrey R. Johnson, Billy W. Newton, Ajay Amar Vashisht, James Akira Wohlschlegel, Nevan J. Krogan, David Paul Toczyski · 2018 · G3 Genes Genomes Genetics
21. Genetic analysis of CHK1 and CHK2 homologues revealed a unique cross talk between ATM and ATR pathways in Neurospora crassa
    Michiyoshi Wakabayashi, Chizu Ishii, Hirokazu Inoue, Shuuitsu Tanaka · 2008 · DNA repair
22. A Role forSaccharomyces cerevisiaeChk1p in the Response to Replication Blocks
    Kaila L. Schollaert, Julie M. Poisson, Jennifer S. Searle, Jennifer A. Schwanekamp, Craig R. Tomlinson, Yolanda Sánchez · 2004 · Molecular Biology of the Cell
23. Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation
    Muriel Grenon, Christine P. Magill, Noel Francis Lowndes, Stephen P. Jackson · 2006 · FEMS Yeast Research
24. Replication protein A is sequentially phosphorylated during meiosis
    George S. Brush · 2001 · Nucleic Acids Research
25. The effects of ionizing radiation on DNA synthesis in eukaryotic cells
    R. Bruce Rowley · 1999 · International Journal of Radiation Biology
26. An Integration of Old and New Perspectives of Mammalian Meiotic Sterility
    Terry Ashley · 2000 · Results and problems in cell differentiation
27. Checkpoints couple transcription network oscillator dynamics to cell-cycle progression
    Sara L. Bristow, Adam R. Leman, Laura A. Simmons Kovacs, Anastasia Deckard, John Harer, Steven B. Haase · 2014 · Genome biology
28. Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants.
    Yu Wang, Terry A. Beerman, David Kowalski · 2001 · PubMed
29. Structural basis of Rad53 kinase activation by dimerization and activation segment exchange
    Leanne E. Wybenga-Groot, Cynthia S.W. Ho, Frédéric D. Sweeney, Derek F. J. Ceccarelli, C. Jane McGlade, Daniel Durocher, Frank Sicheri · 2014 · Cellular Signalling
30. Centrosome-Dependent Bypass of the DNA Damage Checkpoint by the Polo Kinase Cdc5
    Hery Ratsima, Diego Serrano, Cristina Mirela Pascariu, Damien D’Amours · 2016 · Cell Reports
31. Characterization of the Checkpoint Gene RAD53/MEC2 in Saccharomyces cerevisiae
    Sangkyu Kim, Ted A. Weinert · 1997 · Yeast
32. Function of Rad17/Mec3/Ddc1 and its partial complexes in the DNA damage checkpoint
    Jerzy Majka, Peter Burgers · 2005 · DNA repair
33. A Role for Checkpoint Kinase-Dependent Rad26 Phosphorylation in Transcription-Coupled DNA Repair in Saccharomyces cerevisiae
    Taschner, Michael, Harreman, Michelle, Teng, Yumin, Gill, Hefin, Anindya, Roy, Maslen, Sarah L., Skehel, J. Mark, Waters, Raymond, Svejstrup, Jesper Q. · 2010 · Molecular and Cellular Biology
34. Response Mechanisms to Oxidative Stress in Yeast and Filamentous Fungi
    Renata Zadrąg‐Tęcza, Roman Maślanka, Sabina Bednarska, Magdalena Kwolek‐Mirek · 2018 · Springer eBooks
35. Differential regulation of two closely clustered yeast genes, MAG1 and DDI1, by cell-cycle checkpoints
    Y. Zhu, Wei Xiao · 1998 · Nucleic Acids Research
36. TORC1, Tel1/Mec1, and Mpk1 regulate autophagy induction after DNA damage in budding yeast
    Sayuri Ueda, Ryota Ozaki, Atsuki Kaneko, Ryoma Akizuki, Haruko Katsuta, Atsuhiro Miura, Akira Matsuura, Takashi Ushimaru · 2019 · Cellular Signalling
37. Cyclin Regulation by the S Phase Checkpoint
    Gloria Palou, Roger Palou, Ángel Guerra-Moreno, Alba Duch, Anna Travesa, David G. Quintana · 2010 · Journal of Biological Chemistry
38. Recovery from the DNA Replication Checkpoint
    Indrajit Chaudhury, Deanna M. Koepp · 2016 · Genes
39. DNA Damage‐Induced Phosphorylation of Rad55 Protein as a Sentinel for DNA Damage Checkpoint Activation in S. cerevisiae
    Vladimir I. Bashkirov, Kristina Herzberg, Edwin Haghnazari, Alexey S. Vlasenko, Wolf‐Dietrich Heyer · 2006 · Methods in enzymology on CD-ROM/Methods in enzymology
40. Analysis of budding yeast kinases controlled by DNA damage
    Yolanda Sánchez, Zheng Y. Zhou, Mingxia Huang, Bruce E. Kemp, Stephen Joseph Elledge · 1997 · Methods in enzymology on CD-ROM/Methods in enzymology
41. Rad53 Kinase Activation-independent Replication Checkpoint Function of the N-terminal Forkhead-associated (FHA1) Domain
    Brietta L. Pike, Nora Tenis, Jörg Heierhorst · 2004 · Journal of Biological Chemistry
42. Minireview
    Marco Foiani, M Ferrari, Giordano Liberi, Massimo Lopes, Chiara Lucca, F. Marini, Achille Pellicioli, Marco Muzi-Falconi, Paolo Plevani · 1998 · Biological Chemistry
43. DNA decay and limited Rad53 activation after liquid holding of UV-treated nucleotide excision repair deficient S. cerevisiae cells
    Giannattasio, Michele, Lazzaro, Federico, Siede, Wolfram, Nunes, Elia, Plevani, Paolo, Muzi-Falconi, Marco · 2004 · DNA Repair
44. The checkpoint transcriptional response: Make sure to turn it off once you are satisfied
    Marcus Bustamante Smolka, Francisco Meirelles Bastos de Oliveira, Michael R. Harris, Robertus A.M. de Bruin · 2012 · Cell Cycle
45. Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents
    Michael Fasullo, Zheng Dong, Mingzeng Sun, Li Zeng · 2005 · DNA repair
46. Interactions between BRCA Proteins and DNA Structure
    Ralph Scully · 2001 · Experimental Cell Research
47. SiSTL1, encoding a large subunit of ribonucleotide reductase, is crucial for plant growth, chloroplast biogenesis, and cell cycle progression in Setaria italica
    Chanjuan Tang, Sha Tang, Shuo Zhang, Mingzhao Luo, Guanqing Jia, Hui Zhi, Xianmin Diao · 2018 · Journal of Experimental Botany
48. A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1
    Michele Giannattasio, Elena Sommariva, Raffaella Vercillo, Filippo Lippi-Boncambi, Giordano Liberi, Marco Foiani, Paolo Plevani, Marco Muzi-Falconi · 2002 · Proceedings of the National Academy of Sciences
49. Analysis of fission yeast DNA structure checkpoints:1996 Fleming Lecture
    Antony M. Carr · 1998 · Microbiology
50. The FHA Domain, a Phosphoamino Acid Binding Domain Involved in the DNA Damage Response Pathway
    Mingxia Huang, Stephen Joseph Elledge · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
51. SUMOylation regulates pre‐mRNA splicing to overcome DNA damage in fungi
    Yunqing Jian, Xia Chen, Kewei Sun, Zunyong Liu, Danni Cheng, Jie Cao, Jianzhao Liu, Xiaofei Cheng, Liang Wu, Feng Zhang et al. · 2022 · New Phytologist
52. G1/S and G2/M Cyclin-Dependent Kinase Activities Commit Cells to Death in the Absence of the S-Phase Checkpoint
    Nicola Manfrini, Elisa Gobbini, Veronica Baldo, Camilla Trovesi, Giovanna Lucchini, Maria Pia Longhese · 2012 · Molecular and Cellular Biology
53. Fins, limbs, and tails: outgrowths and axial patterning in vertebrate evolution
    Michael I. Coates, Martin J. Cohn · 1998 · BioEssays
54. Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency
    Nerea Sanvisens, Antonia María Romero, Caiguo Zhang, Xiaorong Wu, Xiuxiang An, Mingxia Huang, Sergi Puig · 2016 · Journal of Biological Chemistry
55. Characterization of Checkpoint Responses to DNA Damage in Saccharomyces cerevisiae: Basic Protocols
    Ritu Pabla, Vaibhav Pawar, Hong Zhang, Wolfram Siede · 2006 · Methods in enzymology on CD-ROM/Methods in enzymology
56. Identification of Mutations That Decrease the Stability of a Fragment of Saccharomyces cerevisiae Chromosome III Lacking Efficient Replicators
    James F. Theis, Ann Dershowitz, Carmela Irene, Clelia Maciariello, Michael L Tobin, Giordano Liberi, Sahba Tabrizifard, Malgorzata Korus, Lucia Fabiani, Carol S. Newlon · 2007 · Genetics
57. Maintenance of Mitochondrial DNA by the Caenorhabditis elegans ATR Checkpoint Protein ATL-1
    Chihiro Mori, Takako Takanami, Atsushi Higashitani · 2008 · Genetics
58. Rad9 Comes of Age
    Nancy C. Walworth · 1998 · Science
59. Rad9, a 53BP1 Ortholog of Budding Yeast, Is Insensitive to Spo11-Induced Double-Strand Breaks During Meiosis
    Takehiko Usui, Akira Shinohara · 2021 · Frontiers in Cell and Developmental Biology
60. PCNA antagonizes cohesin-dependent roles in genomic stability
    Caitlin M. Zuilkoski, Robert V. Skibbens · 2020 · PLoS ONE
61. RPA provides checkpoint-independent cell cycle arrest and prevents recombination at uncapped telomeres of Saccharomyces cerevisiae
    Nathalie Grandin, Michel Charbonneau · 2013 · DNA repair
62. Increased expression of the 58-kD microspherule protein (MSP58) is correlated with poor prognosis in glioma patients
    Wei Lin, Xiao-Ming Li, Jing Zhang, Yi Huang, Jiang Wang, Jian Zhang, Xiaofan Jiang, Zhou Fei · 2013 · Medical Oncology
63. PP2ACdc55 dephosphorylates Pds1 and inhibits spindle elongation in S. cerevisiae
    Shoily Khondker, Sam Kajjo, Devon B. Chandler-Brown, Jan Marcel Skotheim, Adam D. Rudner, Amy E. Ikui · 2020 · Journal of Cell Science
64. Cell cycle checkpoint control
    Hiroshi Murakami, Hiroto Okayama · 1997 · Experimental & Molecular Medicine
65. Genetic interaction of RAD53 protein kinase with histones is important for DNA replication
    Teresa M. Holzen, Robert A. Sclafani · 2010 · Cell Cycle
66. Expression of 58-kD Microspherule Protein (MSP58) is Highly Correlated with PET Imaging of Tumor Malignancy and Cell Proliferation in Glioma Patients
    Wei Jen Lin, Shuhui Dai, Tao Chen, Nobuyuki Kawai, Keisuke Miyake, Masaki Okada, Reiji Haba, Yuka Yamamoto, Takashi Tamiya, Zhou Fei · 2016 · Cellular Physiology and Biochemistry
67. The Saccharomyces cerevisiae gene PSO5/RAD16 is involved in the regulation of DNA damage-inducible genes RNR2 and RNR3
    S. O. Paesi-Toresan, Angélica Francesca Maris, Martin Brendel, João Antônio Pêgas Henriques · 1998 · Current Genetics
68. The Role of Chromatin Assembly Factors in Induced Mutagenesis at Low Levels of DNA Damage
    T. А. Evstyukhina, Elena A. Alekseeva, Vyacheslav T. Peshekhonov, И. И. Скобелева, Dmitriy V. Fedorov, В. Г. Королев · 2023 · Genes
69. The analysis of S. cerevisiae cells deleted for mitotic cyclin Clb2 reveals a novel requirement of Sgs1 DNA helicase and Exonuclease 1 when replication forks break in the presence of alkylation damage
    Laurence Signon, Marie Noelle Simon · 2014 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
70. Identification of an N-terminal transcriptional activation domain within Brn3b/POU4f2
    Suzanna E. Martin, Xiuqian Mu, William H. Klein · 2005 · Differentiation
71. Short CommunicationDNA repair by polymerase δ in Saccharomyces cerevisiae is not controlled by the proliferating cell nuclear antigen-like Rad17/Mec3/Ddc1complex
    Jacqueline Moraes Cardone, Martin Brendel, João Antônio Pêgas Henriques · 2008 · Genetics and Molecular Research
72. Is Rad9p Upstream or Downstream from Mec1p?
    Eric J. Foss · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
73. Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers
    Bin-Zhong Li, Richard David Kolodner, Christopher D. Putnam · 2024 · G3 Genes Genomes Genetics
74. Regulators of ribonucleotide reductase inhibit Ty1 mobility in saccharomyces cerevisiae
    John P O'Donnell, Marie Gehman, Jill B. Keeney · 2010 · Mobile DNA
75. PI3K-Related Kinases
    Randal S. Tibbetts, Robert T. Abraham · 2000 · Humana Press eBooks
76. Establishment of a Cell-Free System to Study the Activation of Chk2
    Xingzhi Xu, David F. Stern · 2004 · Humana Press eBooks
77. Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase
    Erika Casari, Renata Tisi, Maria Pia Longhese · 2025 · DNA repair
78. Prevention of DNA Rereplication Through a Meiotic Recombination Checkpoint Response
    Nicole Ann Najor, Layne Weatherford, George S. Brush · 2016 · G3 Genes Genomes Genetics
79. DNA Damage Sensing and Signaling
    Daniel Durocher · 2009 · Springer eBooks
80. Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication
    Laurence Signon · 2017 · G3 Genes Genomes Genetics
81. Orchestration of the DNA damage checkpoint response through the regulation of the protein kinase Rad53.
    Frédéric D. Sweeney · 2010 · TSpace (University of Toronto)
82. PP2A Cdc55 dephosphorylates Pds1 to inhibit spindle elongation
    Shoily Khondker, Sam Kajjo, Devon B. Chandler-Brown, Jan Marcel Skotheim, Adam D. Rudner, Amy E. Ikui · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
83. The puzzling smc5/6 complex : piecing together functions in segregation and repair
    Kristian K. Carlborg · 2015 · Figshare
84. Eukaryotic Replication Origins and Initiation of DNA Replication
    Melvin L. DePamphilis, Mirit I. Aladjem · 2010 · Wiley eBooks
85. Free Histones and the Cell Cycle
    Douglas Maya‐Miles, Macarena Morillo‐Huesca, Sebastián Chávez, Mari Cruz Muñoz-Centeno · 2011 · InTech eBooks
86. Signaling at Stalled Replication Forks
    Daniel A. Mordes, David Cortez · 2009 · Springer eBooks
87. DNA repair by polymerase δ in Saccharomyces cerevisiae is not controlled by the proliferating cell nuclear antigen-like Rad17/Mec3/Ddc1 complex
    Jacqueline Moraes Cardone · 2008
88. Funções da proteína Pso9/Mec3 no controle do ciclo celular e reparação de DNA em Saccharomyces cerevisiae
    Jacqueline Moraes Cardone · 2006 · Americanae (AECID Library)
89. Synthetically Lethal Interactions Classify Novel Genes in Postreplication Repair in Saccharomyces cerevisiae
    Leslie Barbour · 2005 · University Library - University of Saskatchewan (University of Saskatchewan)
90. Genetic and Chemical Genetic Analysis of the Cell Cycle
    Lisa X Yu · 2009 · TSpace (University of Toronto)
91. Phosphorylation events surrounding the DNA damage response in "Saccharomyces cerevisiae"
    Thomas Schleker · 2007 · edoc (University of Basel)
92. Checkpoint Kinase Mediated Regulation of Histone Gene Expression in Response to Genotoxic Stress
    Ugander Reddy Gajjalaiahvari · 2012
93. Determining how chromatin structure is restored after repair of UV damage in Saccharomyces cerevisiae
    Hamed Aula Hamed · 2018 · ORCA Online Research @Cardiff (Cardiff University)
94. Faculty Opinions recommendation of Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase.
    Stephen P. Jackson · 2003 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
95. Cell Cycle Checkpoints
    Errol C. Friedberg, Graham Charles Walker, Wolfram Siede, Richard Dean Wood, Roger Alan Schultz, Tom E. Ellenberger · 2014 · ASM Press eBooks
96. One stop mycology
    Lilyann Novak Frazer · 1996 · Mycological Research
97. Faculty Opinions recommendation of Rif1 and rif2 inhibit localization of tel1 to DNA ends.
    David Shore · 2009 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
98. Safeguarding genome integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 orchestrate Topoisomerase II-mediated catenane resolution in mitosis
    Lucia F. Massari, Alice Finardi, Clara Visintin, Erika Calabrese, Ambra Dondi, Rosella Visintin · 2025 · Nucleic Acids Research
99. Role of the Asf1-Rad53 interaction in genomic stability in S.cerevisiae
    Yue Jiao · 2011 · theses.fr (ABES)
100. DNA DAMAGE SENSORS IN THE CHECKPOINT RESPONSE
     Elizabeth J. Little · 2003 · UA Campus Repository (The University of Arizona)