The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis
Open accessAbstract
Cold temperatures trigger the expression of the CBF family of transcription factors, which in turn activate many downstream genes that confer chilling and freezing tolerance to plants. We report here the identification of ICE1 ( i nducer of C BF e xpression 1 ), an upstream transcription factor that regulates the transcription of CBF genes in the cold. An Arabidopsis ice1 mutant was isolated in a screen for mutations that impair cold-induced transcription of a CBF3 promoter-luciferase reporter gene. The ice1 mutation blocks the expression of CBF3 and decreases the expression of many genes downstream of CBFs , which leads to a significant reduction in plant chilling and freezing tolerance. ICE1 encodes a MYC-like bHLH transcriptional activator. ICE1 binds specifically to the MYC recognition sequences in the CBF3 promoter. ICE1 is expressed constitutively, and its overexpression in wild-type plants enhances the expression of the CBF regulon in the cold and improves freezing tolerance of the transgenic plants.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (1998) · The Plant Cell · doi:10.1105/tpc.10.8.1391 · Cited by 3,044
Stockinger, E. J., Gilmour, S. J., & Thomashow, M. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.1035 · Cited by 1,807
Cited by
Arisz, S. A., van Wijk, R., Roels, W., Zhu, J.-K., Haring, M. A., & Munnik, T. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00001 · Cited by 1,922
Self-citationOrganization of cis-acting regulatory elements in osmotic- and cold-stress-responsive promoters
Yamaguchi-Shinozaki, K., & Shinozaki, K. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2004.12.012 · Cited by 1,458
Research on plant abiotic stress responses in the post‐genome era: past, present and future
Hirayama, T., & Shinozaki, K. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04124.x · Cited by 1,215
Role of DREB transcription factors in abiotic and biotic stress tolerance in plants
Agarwal, P. K., Agarwal, P., Reddy, M. K., & Sopory, S. K. (2006) · Plant Cell Reports · doi:10.1007/s00299-006-0204-8 · Cited by 1,050
Physiological and molecular changes in plants grown at low temperatures
Theocharis, A., Clément, C., & Barka, E. A. (2012) · Planta · doi:10.1007/s00425-012-1641-y · Cited by 773
Metadata
- Authors
- Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.-H., Hong, X., Agarwal, M., & Zhu, J.-K.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2003-04-02
- Volume
- 17
- Issue
- 8
- Pages
- 1043-1054
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2121818799
- Cited by
- 1,673
- References
- 2
- Type
- posted content
- Language
- en
- Open access
- diamond
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis. https://app.cochat.ai/papers/10.1101/gad.1077503
- The paper
- Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.-H., Hong, X., Agarwal, M., & Zhu, J.-K. (2003). ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis. Genes & Development. https://doi.org/10.1101/gad.1077503
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
