Hedgehog: functions and mechanisms

Cites (271)

Items 201–271 of 271

1. Functional differences among Xenopus nodal-related genes in left-right axis determination
   Karuna Sampath, Abby M. S. Cheng, Amanda Frisch · 1997 · Development
2. Sonic hedgehog Regulates Epithelial Proliferation and Cell Survival in the Developing Tooth Germ
   Martyn T. Cobourne, Zoë Hardcastle, Paul Thomas Sharpe · 2001 · Journal of Dental Research
3. The evolution of the hedgehog gene family in chordates: insights from amphioxus hedgehog
   Sebastian M. Shimeld · 1999 · Development Genes and Evolution
4. N- myc Is an Essential Downstream Effector of Shh Signaling during both Normal and Neoplastic Cerebellar Growth
   Beryl A. Hatton, Paul S. Knoepfler, Anna Marie Kenney, David H. Rowitch, Ignacio Moreno de Alborán, James M. Olson, Robert N. Eisenman · 2006 · Cancer Research
5. Proteolysis of Cubitus interruptus in Drosophila requires phosphorylation by Protein Kinase A
   Mary Ann Price, Daniel Kalderon · 1999 · Development
6. Homozygous Mutations in IHH Cause Acrocapitofemoral Dysplasia, an Autosomal Recessive Disorder with Cone-Shaped Epiphyses in Hands and Hips
   Jan Hellemans, Paul J. Coucke, Andres Giedion, Anne De Paepe, Peter Kramer, Frits A. Beemer, Geert R. Mortier · 2003 · The American Journal of Human Genetics
7. FGF9 and SHH regulate mesenchymalVegfaexpression and development of the pulmonary capillary network
   Andrew C. White, Kory J. Lavine, David M. Ornitz · 2007 · Development
8. Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling
   Ryuma Haraguchi, Jun Motoyama, Hiroshi Sasaki, Yoshihiko Satoh, Shinichi Miyagawa, Naomi Nakagata, Anne Moon, Gen Yamada · 2007 · Development
9. Patched1 Haploinsufficiency Increases Adult Bone Mass and Modulates Gli3 Repressor Activity
   Shinsuke Ohba, Hiroshi Kawaguchi, Fumitaka Kugimiya, Toru Ogasawara, Naohiro Kawamura, Taku Saito, Toshiyuki Ikeda, Katsunori Fujii, Tsuyoshi Miyajima, Akira Kuramochi et al. · 2008 · Developmental Cell
10. Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix
    Ainhoa Callejo, Carlos Torroja, Luis Quijada, Isabel Guerrero · 2006 · Development
11. Restriction of sonic hedgehog signalling during early tooth development
    Martyn T. Cobourne, Isabelle Milétich, Paul Thomas Sharpe · 2004 · Development
12. Gli regulation by the opposing activities of Fused and Suppressor of Fused
    Maximilien Murone, Shiuh-Ming Luoh, Donna M. Stone · 2000 · Nature Cell Biology
13. Phosphorylation by Double-Time/CKIε and CKIα Targets Cubitus Interruptus for Slimb/β-TRCP-Mediated Proteolytic Processing
    Jianhang Jia, Lei Zhang, Qing Hua Zhang, Chao Tong, Bing Wang, Fajian Hou, Kazuhito Amanai, Jin Jiang · 2005 · Developmental Cell
14. Loss of the Serine/Threonine Kinase Fused Results in Postnatal Growth Defects and Lethality Due to Progressive Hydrocephalus
    Mark A. Merchant, Marie Evangelista, Shiuh-Ming Luoh, Gretchen D. Frantz, Sreedevi Chalasani, Richard A.D. Carano, Marjie Van Hoy, Julio C. Ramirez, Annie K. Ogasawara, Leanne M. McFarland et al. · 2005 · Molecular and Cellular Biology
15. Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis
    David Monty Berman, Nishita Desai, Xi Wang, Sunil S. Karhadkar, Melissa Reynon, Cory T. Abate-Shen, Philip A. Beachy, Michael M. Shen · 2004 · Developmental Biology
16. Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation
    Naoki Kinto, Masahiro Iwamoto, Motomi Enomoto‐Iwamoto et al. · 1997 · FEBS Letters
17. The role of Sonic hedgehog in neural tube patterning
    I. Patten, Marysia Placzek · 2000 · Cellular and Molecular Life Sciences
18. An Acylatable Residue of Hedgehog Is Differentially Required in Drosophila and Mouse Limb Development
    Jeffrey D. Lee, Petra Kraus, Nicholas Gaiano, Susana Vaz Nery, Jhumku D. Kohtz, Gord Fishell, Cynthia A. Loomis, Jessica E. Treisman · 2001 · Developmental Biology
19. Conditional deletion of Indian hedgehog from collagen type 2α1‐expressing cells results in abnormal endochondral bone formation
    Mohammed Shawkat Razzaque, Desi W. Soegiarto, Datong Chang, Fanxin Long, Beate Lanske · 2005 · The Journal of Pathology
20. Distinct regulators ofShhtranscription in the floor plate and notochord indicate separate origins for these tissues in the mouse node
    Yongsu Jeong, Douglas J. Epstein · 2003 · Development
21. Hedgehog signaling
    Markku T Varjosalo, Jussi Taipale · 2006 · Journal of Cell Science
22. Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus
    David Kent, Erik W. Bush, Joan E. Hooper · 2006 · Development
23. Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2
    Stacey K. Ogden, Manuel Ascano, Melanie A. Stegman, Liza M. Suber, Joan E. Hooper, David J. Robbins · 2003 · Current Biology
24. Mice Deficient in the Fused Homolog Do Not Exhibit Phenotypes Indicative of Perturbed Hedgehog Signaling during Embryonic Development
    Miao-Hsueh Chen, Nan Gao, Takatoshi Kawakami, Pao‐Tien Chuang · 2005 · Molecular and Cellular Biology
25. A critical role for sonic hedgehog signaling in the early expansion of the developing brain
    Joanne Maria Britto, David Tannahill, Roger J. Keynes · 2002 · Nature Neuroscience
26. Reggie‐1/flotillin‐2 promotes secretion of the long‐range signalling forms of Wingless and Hedgehog in Drosophila
    Vladimir L. Katanaev, Gonzalo P. Solis, George Hausmann, Silke Buestorf, Natalya Katanayeva, Yvonne Schrock, Claudia A. O. Stuermer, Konrad Basler · 2008 · The EMBO Journal
27. Incredible journey: how do developmental signals travel through tissue?
    Alan Jian Zhu, Matthew P. Scott · 2004 · Genes & Development
28. Distinct roles of Central missing and Dispatched in sending the Hedgehog signal
    Kazuhito Amanai, Jin Jiang · 2001 · Development
29. Patched2 Modulates Tumorigenesis in Patched1 Heterozygous Mice
    Youngsoo Lee, Heather L. Miller, Helen R. Russell · 2006 · Cancer Research
30. Shh and Ptc are associated with taste bud maintenance in the adult mouse
    Hirohito Miura, Yuko Kusakabe, Chiaki Sugiyama · 2001 · Mechanisms of Development
31. Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein
    Andreu Casali, Gary Struhl · 2004 · Nature
32. Regulation of Left–Right Asymmetries in the Zebrafish by Shh and BMP4
    Thomas Friedrich Schilling, Jean‐Paul Concordet, Philip William Ingham · 1999 · Developmental Biology
33. Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development
    Céline Colnot, Luis de la Fuente, Steve Huang · 2005 · Development
34. Phosphorylation of the fused protein kinase in response to signaling from hedgehog.
    Pascal P. Thérond, James D.R. Knight, Thomas B. Kornberg · 1996 · Proceedings of the National Academy of Sciences
35. Identification of Sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch
    Sharpe, James, Lettice, Laura, Hecksher-Sørensen, Jacob, Fox, Margaret, Hill, Robert, Krumlauf, Robb · 1999 · Current Biology
36. Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells
    Aimin Liu, Alexandra L. Joyner, Daniel H. Turnbull · 1998 · Mechanisms of Development
37. Axial (HNF3β) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter
    Bei‐En Chang, Patrick Blader, Nadine Fischer, Philip William Ingham, Uwe Strähle · 1997 · The EMBO Journal
38. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis
    Patricia E. Kuwabara, Min Ho Lee, Tim Schedl, Gregory S.X.E. Jefferis · 2000 · Genes & Development
39. Structure and expression of Hedgehog, a Drosophila segment-polarity gene required for cell-cell communication
    Tashiro Shigeki, Tatsuo Michiue, Shin‐ichi Higashijima, Shuhei Zenno, Satoshi Ishimaru, Takahashi Fumitaka, Orihara Minako, Tetsuya Kojima, Saigo Kaoru · 1993 · Gene
40. Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling
    Yang Chen, Jean‐René Cardinaux, Richard H. Goodman, Sarah M. Smolik · 1999 · Development
41. The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord
    Néva P. Meyer, Henk Roelink · 2003 · Developmental Biology
42. Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
    Ping Dai, Toshie Shinagawa, Teruaki Nomura, Jun Harada, Sunil C. Kaul, Renu Wadhwa, Md Matiullah Khan, Hiroshi Akimaru, Hiroshi Sasaki, Clemencia Colmenares et al. · 2002 · Genes & Development
43. Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia
    Erica Nieuwenhuis, Jun Motoyama, Paul C. Barnfield, Yoshiaki Yoshikawa, Xiaoyun Zhang, Rong Mo, Michael A. Crackower, Chi‐chung Hui · 2006 · Molecular and Cellular Biology
44. Smoothened translates Hedgehog levels into distinct responses
    Joan E. Hooper · 2003 · Development
45. Hedgehog signalling in foregut malignancy
    D. Neil Watkins, Craig D. Peacock · 2004 · Biochemical Pharmacology
46. Control of chick tectum territory along dorsoventral axis by Sonic hedgehog
    裕二 渡邉, Harukazu Nakamura · 2000 · Development
47. The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment.
    A Pham, Pascal P. Thérond, Georges Alves · 1995 · Genetics
48. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome
    1990 · Trends in Genetics
49. Hedgehog signalling in vascular development
    Takashi Nagase, Miki Nagase, Masafumi Machida, Toshiro Fujita · 2008 · Angiogenesis
50. Growth Factors in Ovarian Development
    Stephanie A. Pangas · 2007 · Seminars in Reproductive Medicine
51. Differential range and activity of various forms of the Hedgehog protein
    Rebecca J. Dawber, Stephen Hebbes, Bram Herpers · 2005 · BMC Developmental Biology
52. The Hedgehog Signaling Pathway as a Target for Anticancer Drug Discovery
    Gary V. Borzillo, Blaise Lippa · 2005 · Current Topics in Medicinal Chemistry
53. Teratogenic compounds of Veratrum californicum (Durand)
    Richard F. Keeler · 1971 · Steroids
54. Sonic hedgehog: restricted expression and limb dysmorphologies
    Robert E. Hill, Simon J. H. Heaney, Laura A. Lettice · 2003 · Journal of Anatomy
55. A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line
    Haruaki Nishimaki, Kenji Kasai, Ken‐ichi Kozaki, Tomohiro Takeo, Hiroshi Ikeda, Shinsuke Saga, Masakazu Nitta, Gen Itoh · 2003 · Biochemical and Biophysical Research Communications
56. Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment
    Armel Gallet, Pascal P. Thérond · 2004 · Developmental Biology
57. Genetic Dissection of the Drosophila Cubitus interruptus Signaling Complex
    Mark A. Lefers, Q.Tian Wang, Robert A. Holmgren · 2001 · Developmental Biology
58. The role of kinases in the Hedgehog signalling pathway
    Reid A. Aikin, Katie L. Ayers, Pascal P. Thérond · 2008 · EMBO Reports
59. TERATOGENIC COMPOUNDS OF VERATRUM CALIFORNICUM (DURAND): I. PREPARATION AND CHARACTERIZATION OF FRACTIONS AND ALKALOIDS FOR BIOLOGIC TESTING
    Richard F. Keeler, Wayne Binns · 1966 · Canadian Journal of Biochemistry
60. Epithelial expression of SHH signaling pathway in odontogenic tumors
    Lu Zhang, Xinming Chen, Zhi‐Jun Sun · 2005 · Oral Oncology
61. THE REACTION OF PHENYLMETHANESULFONYL CHLORIDE WITH TERTIARY AMINES: FORMATION OF GEOMETRICAL ISOMERS ABOUT A CARBON–SULFUR DOUBLE BOND
    JAMES FREDERICK KING, Tony Durst · 1966 · Canadian Journal of Chemistry
62. Genomewide Expression Profiling in the Zebrafish Embryo Identifies Target Genes Regulated by Hedgehog Signaling During Vertebrate Development
    Jun Xu, Bhylahalli Purushottam Srinivas, Shang Yew Tay, Alicia Mak, Xianwen Yu, Serene G.P. Lee, Henry He Yang, Kunde Ramamoorthy Govindarajan, Bernard Leong, Guillaume Bourque et al. · 2006 · Genetics
63. Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina
    Crystal Sigulinsky, Eric S. Green, Anna M. Clark, Edward M. Levine · 2008 · Developmental Biology
64. Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma
    Roland Kappler, Regine Bauer, Julia Calzada‐Wack · 2004 · Oncogene
65. Hedgehog Signaling Pathway
    Leni S. Jacob, Lawrence Lum · 2007 · Science s STKE
66. Several PATCHED1 Missense Mutations Display Activity in patched1-Deficient Fibroblasts
    Evans C. Bailey, Ljiljana Milenković, Matthew P. Scott · 2002 · Journal of Biological Chemistry
67. Genome duplications of early vertebrates as a possible chronicle of the evolutionary history of the neural crest
    Hiroshi Wada, Kaz Makabe · 2006 · International Journal of Biological Sciences
68. Hedgehog Drugs Begin To Show Results
    K. Garber · 2008 · JNCI Journal of the National Cancer Institute
69. Expression patterns of hedgehog, wingless, and decapentaplegic during gut formation of Gryllus bimaculatus (cricket)
    Yoshiko Inoue, Nao Niwa, Taro Mito · 2002 · Mechanisms of Development
70. Accelerated Induction of Bladder Cancer in Patched Heterozygous Mutant Mice
    Sahar M. Hamed, Hélène LaRue, Hélène Hovington · 2004 · Cancer Research
71. Hedgehog Signaling Pathway in Drosophila
    Leni S. Jacob, Lawrence Lum · 2007 · Science s STKE