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Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light
Open accessAbstract
Plant photoreceptors mediate light suppression of the E3 ubiquitin ligase COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1) to affect gene expression and photomorphogenesis. However, how photoreceptors mediate light regulation of COP1 activity remains unknown. We report here that Arabidopsis blue-light receptor cryptochrome 1 (CRY1) undergoes blue-light-dependent interaction with the COP1-interacting protein SPA1 (SUPPRESSOR OF PHYTOCHROME A). We further show that the CRY1–SPA1 interaction suppresses the SPA1–COP1 interaction and COP1-dependent degradation of the transcription factor HY5. These results are consistent with a hypothesis that photoexcited CRY1 interacts with SPA1 to modulate COP1 activity and plant development.
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Cited by
Huché-Thélier, L., Crespel, L., Gourrierec, J. L., Morel, P., Sakr, S., & Leduc, N. (2016) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2015.06.009 · Cited by 458
Phytochrome signaling mechanisms and the control of plant development
Chen, M., & Chory, J. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.07.002 · Cited by 448
Zuo, Z., Liu, H., Liu, B., Liu, X., & Lin, C. (2011) · Current Biology · doi:10.1016/j.cub.2011.03.048 · Cited by 431
Self-citationCircadian Clock and Photoperiodic Flowering in Arabidopsis: CONSTANS Is a Hub for Signal Integration
Shim, J. S., Kubota, A., & Imaizumi, T. (2017) · Plant Physiology · doi:10.1104/pp.16.01327 · Cited by 359
Shade avoidance: phytochrome signalling and other aboveground neighbour detection cues
Pierik, R., & de Wit, M. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/ert389 · Cited by 298
Metadata
- Authors
- Liu, B., Zuo, Z., Liu, H., Liu, X., & Lin, C.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2011-04-21
- Volume
- 25
- Issue
- 10
- Pages
- 1029-1034
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2133679788
- Cited by
- 390
- References
- 0
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Liu, B., Zuo, Z., Liu, H., Liu, X., & Lin, C. (2011). Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light. Genes & Development. https://doi.org/10.1101/gad.2025011
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