Senescent cells develop a parp-1 and nuclear factor-κB-associated secretome (PNAS).

Cited by (267)

Items 101–200 of 267

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2. Cellular senescence or stemness: hypoxia flips the coin
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3. NF1 loss induces senescence during human melanocyte differentiation in an iPSC ‐based model
   Lionel Larribère, Huizi Wu, Daniel Novak, Marta Galach, Mathias Bernhardt, Elias Orouji, Kasia Weina, Nathalie Knappe, Christos Sachpekidis, Ludmila Umansky et al. · 2015 · Pigment Cell & Melanoma Research
4. Chemokines orchestrate tumor cells and the microenvironment to achieve metastatic heterogeneity
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5. Senescent cardiac fibroblasts: A key role in cardiac fibrosis
   José Miguel Osorio, Claudio Espinoza-Pérez, Constanza Rimassa-Taré, Víctor Machuca, Juan Ortega Bustos, Matías Vallejos, Héctor Vargas, Guillermo Dı́az-Araya · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
6. Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells
   Dana Koludrović, Patrick Laurette, Thomas Strub, Céline Keime, Madeleine Le Coz, Sébastien Coassolo, Gabrielle Mengus, Lionel Larue, Irwin Davidson · 2015 · PLoS Genetics
7. Healthy Tendon Stem Cell‐Derived Exosomes Promote Tendon‐To‐Bone Healing of Aged Chronic Rotator Cuff Tears by Breaking the Positive‐Feedback Cross‐Talk between Senescent Tendon Stem Cells and Macrophages through the Modulation of Macrophage Polarization
   Xuancheng Zhang, Wei Dong Song, Yang Liu, Kang Han, Yuxu Wu, Eunshinae Cho, Zhaoyi Fang, Lianghua Jiang, Yihe Hu, Xuesong Zhu et al. · 2024 · Small
8. Subcellular structure, heterogeneity, and plasticity of senescent cells
   Thais Cardoso Bitencourt, José Eduardo Vargas, Andrew Oliveira Silva, Lucas Rosa Fraga, Eduardo Cremonese Filippi‐Chiela · 2024 · Aging Cell
9. Nuclear ADP-ribosylation drives IFNγ-dependent STAT1α enhancer formation in macrophages
   Rebecca Gupte, Tulip Sunil Nandu, W. Lee Kraus · 2021 · Nature Communications
10. An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis
    Jun‐ichi Abe, Masaki Imanishi, Shengyu Li, Aijun Zhang, Kyung Ae Ko, Venkata Subrahman K Samanthapudi, Ling-Ling Lee, Angelica Paniagua-Bojorges, Young Jin Gi, Brian Paul Hobbs et al. · 2023 · Circulation Research
11. Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis
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12. Mechanisms involved in hematopoietic stem cell aging
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13. Chemokines and Cytokines in Immunotherapy of Melanoma and Other Tumors: From Biomarkers to Therapeutic Targets
    Robin Reschke, Alexander Heinrich Enk, Jessica C. Hassel · 2024 · International Journal of Molecular Sciences
14. IκBζ is a regulator for the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence
    Eva Alexander, Dominic G. Hildebrand, Anna Kriebs, Kerstin Obermayer, Marianne Manz, Oliver C. Rothfuss, Frank Eßmann, Klaus Schulze‐Osthoff · 2013 · Journal of Cell Science
15. Effect of Cellular Senescence on the Growth of HER2-Positive Breast Cancers
    Mariano F. Zacarías Fluck, Beatriz Morancho, Rocío Vicario, Antonio Luque-García, Marta Escorihuela, Josep Villanueva, Isabel Teresa Rubio, Joaquı́n Arribas · 2015 · JNCI Journal of the National Cancer Institute
16. P21-PARP-1 Pathway Is Involved in Cigarette Smoke-Induced Lung DNA Damage and Cellular Senescence
    Hongwei Yao, Isaac Kirubakaran Sundar, Vera A. Gorbunova, Irfan Rahman · 2013 · PLoS ONE
17. Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells
    Justine Leclerc, David Garandeau, Charlotte Pandiani, Céline Gaudel, Karine Bille, Nicolas Nottet, Virginie Garcia, Pascal Colosetti, Sophie Pagnotta, Philippe Bahadoran et al. · 2018 · Oncogene
18. The MITF regulatory network in melanoma
    Jagat Singh Chauhan, Michael Hölzel, Jean‐Philippe Lambert, Francesca Meteora Buffa, Colin R. Goding · 2022 · Pigment Cell & Melanoma Research
19. Thymine DNA glycosylase as a novel target for melanoma
    Pietro Mancuso, Rossella Tricarico, Vikram Bhattacharjee, Laura Cosentino, Yuwaraj Kadariya, Jaroslav Jelı́nek, Émmanuelle Nicolas, Margret B. Einarson, Neil Beeharry, Karthik Devarajan et al. · 2019 · Oncogene
20. BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes
    Peter J. Thompson, Ajit N. Shah, Charalampia-Christina Apostolopolou, Anil Bhushan · 2019 · International Journal of Molecular Sciences
21. MITF, the Janus Transcription Factor of Melanoma
    Dana Koludrović, Irwin Davidson · 2013 · Future Oncology
22. Approaches to treat pulmonary arterial hypertension by targeting BMPR2: from cell membrane to nucleus
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23. Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression
    Caroline Bonet, Flavie Luciani, Jean‐François Ottavi, Justine Leclerc, Fanélie-Marie Jouenne, Marina Boncompagni, Karine Bille, Véronique Hofman, Guillaume Bossis, Gian Marco De Donatis et al. · 2016 · JNCI Journal of the National Cancer Institute
24. Senescence and Host–Pathogen Interactions
    Daniel Humphreys, Mohamed ElGhazaly, Teresa Frisan · 2020 · Cells
25. Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells
    Youssef Al Hmada, Robert Thomas Brodell, Naji Kharouf, Thomas Wayne Flanagan, Abdulhadi A. AlAmodi, Sofie-Yasmin Hassan, Hosam Shalaby, Sarah-Lilly Hassan, Youssef Haïkel, Mosaad Megahed et al. · 2024 · Cancers
26. NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug
    Simona Caporali, Lauretta Levati, Grazia Graziani, Alessia Muzi, Maria Grazia Atzori, Enzo Bonmassar, Giuseppe Palmieri, Paolo A. Ascierto, Stefania D’Atri · 2012 · Journal of Translational Medicine
27. Pathways from senescence to melanoma: focus on MITF sumoylation
    J Leclerc, Robert Ballotti, Corine Bertolotto · 2017 · Oncogene
28. Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma
    Gabriela Maria Wiedemann, Celina Aithal, Angelina Kraechan, Constanze Heise, Bruno Loureiro Cadilha, Jin Zhang, Peter Duewell, Robert Ballotti, Stefan Endres, Corine Bertolotto et al. · 2018 · Translational Oncology
29. Endothelial SIRT1 as a Target for the Prevention of Arterial Aging: Promises and Challenges
    Musammat Kulsuma Begum, Daniels Konja, Sandeep Singh, Stefan Chłopicki, Yu Wang · 2021 · Journal of Cardiovascular Pharmacology
30. Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program
    Mazzucco, Anna E., Smogorzewska, Agata, Kang, Chanhee, Luo, Ji, Schlabach, Michael R., Xu, Qikai, Patel, Rupesh, Elledge, Stephen J. · 2017 · Genes & Development
31. DNA damage response(DDR): a link between cellular senescence and human cytomegalovirus
    Xinna Wu, Xuqiang Zhou, Sanying Wang, Genxiang Mao · 2023 · Virology Journal
32. O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer
    Yi Zhang, Shuyan Zhou, Yan Kai, Ya-qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel, Julie Belmar, Xiaoyan Zheng, Junfeng Ma et al. · 2024 · Nature Communications
33. FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells
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34. mTOR as a senescence manipulation target: A forked road
    Sarah Saoudaoui, Monique Bernard, Guillaume B. Cardin, Nicolas Malaquin, Apostolos Christopoulos, Françis Rodier · 2021 · Advances in cancer research
35. Cancer oxidative stress and dietary antioxidants
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36. Influence of the microenvironment on modulation of the host response by typhoid toxin
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37. Dysregulated RNA processing and metabolism: a new hallmark of ageing and provocation for cellular senescence
    Lorna W. Harries · 2022 · FEBS Journal
38. Exploring the role of senescence inducers and senotherapeutics as targets for anticancer natural products
    Abdullah Al Mamun, Mohammad Abu Sufian, Md. Sahab Uddin, Dewan Md. Sumsuzzman, Philippe Jeandet, Mohammad Safiqul Islam, Hongjie Zhang, Ah‐Ng Tony Kong, Md Shahid Sarwar · 2022 · European Journal of Pharmacology
39. PARP1 at the crossroad of cellular senescence and nucleolar processes
    Kinga Kołacz-Milewska, Agnieszka Robaszkiewicz · 2024 · Ageing Research Reviews
40. Bioactive Oligopeptides from Ginseng (Panax ginseng Meyer) Suppress Oxidative Stress-Induced Senescence in Fibroblasts via NAD+/SIRT1/PGC-1α Signaling Pathway
    Na Zhu, Meihong Xu, Yong Li · 2022 · Nutrients
41. The PARP Enzyme Family and the Hallmarks of Cancer Part 2: Hallmarks Related to Cancer Host Interactions
    Máté Ágoston Demény, László Virág · 2021 · Cancers
42. A nutrigeroscience approach: Dietary macronutrients and cellular senescence
    Mariah F. Calubag, Paul D. Robbins, Dudley W. Lamming · 2024 · Cell Metabolism
43. Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells
    Jennyfer Martínez, Doménica Tarallo, Laura Martínez Palma, Sabina Victoria, Mariana Bresque, Sebastián Rodríguez-Bottero, Inés Marmisolle, Carlos Escande, Patricia Cassina, Gabriela Casanova et al. · 2019 · Biochemical Journal
44. Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells
    Jhen‐Wei Ruan, Yi‐Chu Liao, Ingrid Lua, Ming-Hsun Li, Chih-Yi Hsu, Ji Hshiung Chen · 2012 · Breast Cancer Research
45. BRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1
    Johannes Grimm, Anita Hufnagel, Marion Wobser, Andreas Borst, Sebastian Haferkamp, Roland Houben, Svenja Meierjohann · 2018 · Oncogenesis
46. Endothelial Senescence and Its Impact on Angiogenesis in Alzheimer’s Disease
    Irina Georgieva, Jana Dimitrova Tchekalarova, Dimitar Borisov Iliev, Rumiana Tzoneva · 2023 · International Journal of Molecular Sciences
47. c-Jun N-terminal kinase signaling in cellular senescence
    Ying Deng, Vojtěch Adam, Eugenie Nepovimová, Zbyněk Heger, Marián Valko, Qinghua Wu, Wei Wei, Kamil Kuča · 2023 · Archives of Toxicology
48. HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome
    Simona Di Martino, Carla Azzurra Amoreo, Barbara Nuvoli, Rossella Galati, Sabrina Strano, Francesco Facciolo, Gabriele Alessandrini, Harvey Ira Pass, Gennaro Ciliberto, Giovanni Blandino et al. · 2018 · Oncogene
49. Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
    Parmjit Jat, Neil D. Perkins, Sophia N. Mowla · 2013 · OncoTargets and Therapy
50. Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells
    Emilly S. Villodre, Franciele Cristina Kipper, Andrew Oliveira Silva, Guido Lenz, Patrícia Luciana da Costa Lopez · 2017 · Molecular Neurobiology
51. MITF induces escape from innate immunity in melanoma
    Luís Sánchez‐del‐Campo, Román Martí-Díaz, María Fernanda Montenegro, Rebeca González-Guerrero, Trinidad Hernández‐Caselles, Enrique Martínez‐Barba, Antonio Piñero, Juan Cabezas‐Herrera, Colin R. Goding, José Neptuno Rodríguez‐López · 2021 · Journal of Experimental & Clinical Cancer Research
52. CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance
    Arthur Gautron, Laura Bachelot, Marc Aubry, Delphine Leclerc, Anaïs M. Quéméner, Sébastien Corre, Florian Rambow, Anaïs Paris, Nina Tardif, Héloïse M. Leclair et al. · 2021 · EMBO Molecular Medicine
53. New Insights into Therapy-Induced Progression of Cancer
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54. Autophagy and PTEN in DNA damage-induced senescence
    Arishya Sharma, Alexandru Almasan · 2021 · Advances in cancer research
55. Targeting Mitochondria to Control Ageing and Senescence
    Margherita Protasoni, Manuel Serrano · 2023 · Pharmaceutics
56. Inherited variation in the PARP1 gene and survival from melanoma
    John R. Davies, Rosalyn Jewell, Paul Affleck, Gabriella M. Anic, Juliette A. Randerson‐Moor, Aija Ozola, Kathleen M. Egan, Faye Elliott, Zaida García‐Casado, Johan Hansson et al. · 2014 · International Journal of Cancer
57. Epigenetics and senescence: Learning from the INK4-ARF locus
    Elisabeth Simboeck, Joana Domingues Ribeiro, Sophia Teichmann, Luciano Di Croce · 2011 · Biochemical Pharmacology
58. Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy
    Nozomi Tomimatsu, Luis Fernando Macedo Di Cristofaro, Suman Kanji, Lorena Samentar, Benjamin Russell Jordan, Ralf Kittler, Amyn A. Habib, Jair Machado Espíndola‐Netto, Tamar Tchkonia, James L. Kirkland et al. · 2025 · EMBO Molecular Medicine
59. Oncogene‐induced senescence and melanoma: where do we stand?
    Daniel S. Peeper · 2011 · Pigment Cell & Melanoma Research
60. TBX 2 expression is regulated by PAX 3 in the melanocyte lineage
    Fang Liu, Juxiang Cao, Jinghu Lv, Liang Dong, Eric Pier, George Xu, Rui‐an Wang, Zhixiang Xu, Colin R. Goding, Rutao Cui · 2012 · Pigment Cell & Melanoma Research
61. Cellular senescence and frailty: a comprehensive insight into the causal links
    Serena Marcozzi, Giorgia Bigossi, Maria Elisa Giuliani, Robertina Giacconi, Francesco Piacenza, Maurizio Cardelli, Dario Brunetti, Agnese Segala, Alessandra Valerio, Enzo Nisoli et al. · 2023 · GeroScience
62. Non‐canonical ATM/MRN activities temporally define the senescence secretory program
    Nicolas Malaquin, Audrey Carrier-Leclerc, Aurélie Martinez, Mireille Dessureault, Sabrina Ghadaouia, Jean‐Philippe Coppé, Stéphanie Nadeau, Guillaume Cardin, Judith Campisi, Françis Rodier · 2020 · EMBO Reports
63. Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis
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64. Cooperative behaviour and phenotype plasticity evolve during melanoma progression
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65. Vitamin K: New insights related to senescence and cancer metastasis
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66. Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas
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67. Cockayne Syndrome Type A Protein Protects Primary Human Keratinocytes from Senescence
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68. Stress-induced Norepinephrine Downregulates CCL2 in Macrophages to Suppress Tumor Growth in a Model of Malignant Melanoma
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69. Diallyl disulfide inhibits TNFα-induced CCL2 release by MDA-MB-231 cells.
    David Bauer, ELIZABETH A. MAZZIO, Karam F. A. Soliman, Equar Taka, Ebenezer T. Oriaku, Tracey Womble, Selina Darling‐Reed · 2014 · PubMed
70. MITF-Independent Pro-Survival Role of BRG1-Containing SWI/SNF Complex in Melanoma Cells
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71. Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy
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72. Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?
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73. The Cross Talk between Cellular Senescence and Melanoma: From Molecular Pathogenesis to Target Therapies
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74. PJ-34 inhibits PARP-1 expression and ERK phosphorylation in glioma-conditioned brain microvascular endothelial cells
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75. Caerin 1.1/1.9 Enhances Antitumour Immunity by Activating the IFN-α Response Signalling Pathway of Tumour Macrophages
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76. Cellular senescence and ophthalmic diseases: narrative review
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77. Tumor Protein p63/Nuclear Factor κB Feedback Loop in Regulation of Cell Death
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78. Crosstalk signaling in targeted melanoma therapy
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79. Targeting cellular senescence to combat cancer and ageing
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80. Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-Mhigh melanoma cell populations
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82. Cellular Senescence and Ageing
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83. Metabolic regulation of endothelial senescence
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93. Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights
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96. The PARP inhibitor olaparib promotes senescence in murine macrophages
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100. Cellular senescence, neuroinflammation, and microRNAs: Possible interactions driving aging and neurodegeneration in the hippocampal neurogenic niche
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