Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits

Cited by (367)

Items 201–300 of 367

1. Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles
   Ken Sin Lo, Swarooparani Vadlamudi, Marie P. Fogarty, Karen L. Mohlke, Guillaume Lettre · 2014 · Genomics
2. FOXP4-AS1 is a favorable prognostic-related enhancer RNA in ovarian cancer
   Tian Hua, Yunjie Tian, Ruimin Wang, Cai-fen Zhao, Yun-hong Kong, Ruiqing Tian, Wei Ting Wang, Lixia Ma · 2021 · Bioscience Reports
3. Profiling Celiac Disease-Related Transcriptional Changes
   Ainara Castellanos–Rubio, José Ramón Bilbao · 2017 · International review of cytology
4. C3D: a tool to predict 3D genomic interactions between cis-regulatory elements
   Tahmid Mehdi, Swneke Donovan Bailey, Paul Guilhamon, Mathieu Lupien · 2018 · Bioinformatics
5. Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C
   Ning Liu, Wai Yee Low, Hamid Alinejad‐Rokny, Stephen Pederson, Timothy J. Sadlon, Simon Charles Barry, James Breen · 2021 · Epigenetics & Chromatin
6. Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing
   Jubao Duan · 2015 · Neuroscience Bulletin
7. A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus
   Sándor Spisák, Viktória Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Bálint Pataki, Dezső Ribli, Zsófia M. Sztupinszki, Connor A. Bell, Mersedeh Rohanizadegan, David R. Stillman et al. · 2023 · Nature Communications
8. Functional characterization of the C7ORF76 genomic region, a prominent GWAS signal for osteoporosis in 7q21.3
   Neus Roca‐Ayats, Núria Martínez‐Gil, Mónica Cozar, Marina Gerousi, Natalia García‐Giralt, Diana Ovejero, Leonardo Mellibovsky, Xavier Nogués, Adolfo Díez‐Pérez, Daniel Grinberg et al. · 2019 · Bone
9. Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease
   Xi Fu, Kathy Nga-Chu Lui, Clara Sze-Man Tang, Ray Kit Ng, Frank Pui-Ling Lai, Sin-Ting Lau, Zhixin Li, María-Mercé García-Barceló, Pak Chung Sham, Paul Kwong Hang Tam et al. · 2020 · Genome Research
10. Super-enhancers: drivers of cells’ identities and cells’ debacles
    Mélanie Lavaud, Robel A. Tesfaye, Léa Lassous, Bénédicte Brounais-Le Royer, Marc Baud’huin, Franck Verrecchia, François Lamoureux, Steven Georges, Benjamin Ory · 2024 · Epigenomics
11. Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies
    Brielin C. Brown, Alkes L. Price, Nikolaos A. Patsopoulos, Noah Zaitlen · 2016 · Genetics
12. Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer–target gene regulatory interactions
    Elisa Salviato, Vera Djordjilović, Judith Mary Hariprakash, Ilario Tagliaferri, Koustav Pal, Francesco Ferrari · 2021 · Nucleic Acids Research
13. In-vitro function of upstream visfatin polymorphisms that are associated with adverse cardiometabolic parameters in obese children
    Delicia Shu Qin Ooi, Siong Gim Ong, Chew‐Kiat Heng, Kah Yin Loke, Yung Seng Lee · 2016 · BMC Genomics
14. The regulatory landscapes of human ovarian ageing
    Jin Chen, Xizhe Wang, Adam D. Hudgins, Amir Gamliel, Mingzhuo Pei, Seung-Soo Kim, Daniela Contreras, Jan H.J. Hoeijmakers, Judith Campisi, Rogerio A. Løbo et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
15. Stem Cell-Derived β Cells: A Versatile Research Platform to Interrogate the Genetic Basis of β Cell Dysfunction
    Alberto Bartolomé · 2022 · International Journal of Molecular Sciences
16. A comprehensive comparison of multilocus association methods with summary statistics in genome-wide association studies
    Zhonghe Shao, Ting Wang, Jiahao Qiao, Yuchen Zhang, Shuiping Huang, Ping Zeng · 2022 · BMC Bioinformatics
17. SNPs associated with colorectal cancer at 15q13.3 affect risk enhancers that modulate GREM1 gene expression
    Barbara K. Fortini, Stephanie Tring, Matthew A.M. Devall, Mourad W. Ali, Sarah J. Plummer, Graham Casey · 2021 · Human Mutation
18. Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production
    Laavanya Sankaranarayanan, Kelly Brewer, Shauna Morrow, Graham D. Johnson, Alejandro Barrera, Revathy Venukuttan, Ryan K. Sisk, Andrea Elizabeth Dunaif, Timothy E. Reddy · 2025 · Nature Communications
19. An encyclopedia of human enhancer–gene regulatory interactions
    Andreas R. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh, Maya U. Sheth, Kushal K. Dey, Evelyn Jagoda, Ramil Nurtdinov, Wang Xi, Anthony S. Tan, James Galante et al. · 2026 · Nature
20. Recognition of long-range enhancer-promoter interactions by adding genomic signatures of segmented regulatory regions
    Zhenxing Feng, Qian‐Zhong Li · 2017 · Genomics
21. Integrated gene-based and pathway analyses using UK Biobank data identify novel genes for chronic respiratory diseases
    Lijuan Wang, Rui Fang, Meng Zhu, Na Qin, Yuzhuo Wang, Jingyi Fan, Qi Sun, Mengmeng Ji, Xikang Fan, Junxing Xie et al. · 2020 · Gene
22. Haplotype-specific chromatin looping reveals genetic interactions of regulatory regions modulating gene expression in 8p23.1
    Mariana Saint Just Ribeiro, Pulak Tripathi, Bahram Namjou, John B. Harley, Iouri Chepelev · 2022 · Frontiers in Genetics
23. Association of XRCC1 Arg399Gln and Arg194Trp polymorphisms with susceptibility to multiple autoimmune diseases: a meta-analysis
    Mengle Peng, Xueliang Zhou, Xianfei Ding, Li-Qiang Wei, Yong Zhao, Tao Zhu, Xiaoqing Shi, Dongchun Qin · 2016 · Rheumatology International
24. Modeling common and rare genetic risk factors of neuropsychiatric disorders in human induced pluripotent stem cells
    Abdurrahman W. Muhtaseb, Jubao Duan · 2022 · Schizophrenia Research
25. Sex Significantly Impacts the Function of Major Depression–Linked Variants In Vivo
    Bernard Mulvey, Din Selmanovic, Joseph D. Dougherty · 2021 · Biological Psychiatry
26. Bioinformatics approaches to predict target genes from transcription factor binding data
    Alexandra Essebier, Marnie L. Lamprecht, Michael Piper, Mikael Bodén A · 2017 · Methods
27. Efficient Prioritization of Multiple Causal eQTL Variants via Sparse Polygenic Modeling
    Naoki Nariai, William W. Young Greenwald, Christopher DeBoever, He Li, Kelly A. Frazer · 2017 · Genetics
28. A PreSTIGEous use of LncRNAs to predict enhancers
    Shino Murakami, Shrikanth S. Gadad, WL Kraus · 2015 · Cell Cycle
29. Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation
    Heekyoung Lee, Kun Qian, Christine von Toerne, Lena Hoerburger, Melina Claussnitzer, Christoph Hoffmann, Viktoria Glunk, Simone Wahl, Michaela Breier, Franziska Eck et al. · 2017 · Nucleic Acids Research
30. Translating GWAS in rheumatic disease: approaches to establishing mechanism and function for genetic associations with ankylosing spondylitis
    Julie A. Osgood, Julian Charles Knight · 2018 · Briefings in Functional Genomics
31. Association of the Rheumatoid Arthritis Severity Variant rs26232 with the Invasive Activity of Synovial Fibroblasts
    Emma Dorris, Eimear Linehan, Michelle Trenkmann, Douglas James Veale, Ursula Fearon, Anthony Gerard Wilson · 2019 · Cells
32. Identification of Enhancer RNA CDK6-AS1 as a Potential Novel Prognostic Biomarker in Gastric Cancer
    Shifeng Yang, Xiaoming Zou, Hao Yang, Jiacheng Li, Ange Zhang, Lisha Zhang, Changjian Li, Lei Zhu, Zhen Ma · 2022 · Frontiers in Genetics
33. Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity
    Mette Korre Andersen, Lars Henrik Ängquist, Jette Bork‐Jensen, Anna Elisabet Jonsson, Sara Elizabeth Stinson, Camilla Helene Sandholt, Malte Thodberg, Laura Maarit Pikkupeura, Emily L. Ongstad, Niels Grarup et al. · 2023 · Diabetes Care
34. Breaking enhancers to gain insights into developmental defects
    Daniel A. Armendariz, Anjana Sundarrajan, Gary C. Hon · 2023 · eLife
35. Epigenomic Consequences of Coding and Noncoding Driver Mutations
    Xiaosai Yao, Manjie Xing, Wen Fong Ooi, Patrick B. O. Tan, Bin Tean Teh · 2016 · Trends in cancer
36. A Guided Tour to Computational Haplotyping
    Gunnar W. Klau, Tobias Marschall · 2017 · Lecture notes in computer science
37. Integrative Approaches to Understanding the Pathogenic Role of Genetic Variation in Rheumatic Diseases
    Vincent A. Laufer, Jake Y. Chen, Carl D. Langefeld, S. Louis Bridges · 2017 · Rheumatic Disease Clinics of North America
38. Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion
    Antonio Vitobello, Juliane Perner, Johanna Beil, Jiang Zhu, Alberto Del Río-Espínola, Laurent Morawiec, Magdalena Westphal, Valérie Dubost, Marc Altorfer, Ulrike Naumann et al. · 2019 · Life Science Alliance
39. Analysis of open chromatin regions in bladder cancer links β-catenin mutations and Wnt signaling with neuronal subtype of bladder cancer
    Aleyna Eray, Perihan Yagmur Guneri-Sozeri, Gülden Özden-Yılmaz, Gökhan Karakülah, Serap Erkek · 2020 · Scientific Reports
40. Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs
    Katarina Tengvall, Sergey V. Kozyrev, Marcin Kierczak, Kerstin Bergvall, Fabiana Farias, Brita Ardesjö-Lundgren, Mia Olsson, Eva Murén, Ragnvi Hagman, Tosso Leeb et al. · 2016 · BMC Genetics
41. Mammalian genome writing: Unlocking new length scales for genome engineering
    Sudarshan Pinglay, John T. Atwater, Ran Brosh, Jay Shendure, Matthew T. Maurano, Jef D. Boeke · 2026 · Cell
42. Genome-wide association study of host resistance to the ectoparasite Ichthyophthirius multifiliis in the Amazon fish Colossoma macropomum
    Lieschen Valeria Guerra Lira, Vito A. Mastrochirico-Filho, Natália J. Mendes, Raquel B. Ariede, José Manuel Yañez, Diogo Teruo Hashimoto · 2022 · Molecular Biology Reports
43. Chronic lymphocytic leukemia (CLL) risk is mediated by multiple enhancer variants within CLL risk loci
    Huihuang Yan, Shulan Tian, Geffen Kleinstern, Zhiquan Wang, Jeong‐Heon Lee, Nicholas James Boddicker, James R. Cerhan, Neil E. Kay, Esteban Braggio, Susan L. Slager · 2020 · Human Molecular Genetics
44. Gender specific eRNA TBX5-AS1 as the immunological biomarker for male patients with lung squamous cell carcinoma in pan-cancer screening
    Tao Yan, Kai Wang, Qidi Zhao, Junjie Zhuang, Hongchang Shen, Guoyuan Ma, Lei Cong, Jiajun Du · 2021 · PeerJ
45. Simultaneous test and estimation of total genetic effect in eQTL integrative analysis through mixed models
    Ting Wang, Jiahao Qiao, Shuo Zhang, Yongyue Wei, Ping Zeng · 2022 · Briefings in Bioinformatics
46. EPIXplorer: A web server for prediction, analysis and visualization of enhancer-promoter interactions
    Li Tang, Zhizhou Zhong, Yisheng Lin, Yifei Yang, Jun Wang, James F. Martin, Min Li · 2022 · Nucleic Acids Research
47. Predicting enhancer-promoter interaction based on epigenomic signals
    Leqiong Zheng, Li Liu, Wen Zhu, Yijie Ding, Fang‐Xiang Wu · 2023 · Frontiers in Genetics
48. Short-Circuiting Gene Regulatory Networks: Origins of B Cell Lymphoma
    Olivia I. Koues, Eugene M. Oltz, Jacqueline E. Payton · 2015 · Trends in Genetics
49. A powerful approach reveals numerous expression quantitative trait haplotypes in multiple tissues
    Dingge Ying, Mulin Jun Li, Pak Chung Sham, Miaoxin Li · 2018 · Bioinformatics
50. Role of Non-Coding Variants in Brugada Syndrome
    Adrian Pérez-Agustín, Mel·lina Pinsach‐Abuin, Sara Pagans · 2020 · International Journal of Molecular Sciences
51. Towards functional maps of non-coding variants in cancer
    Yihan Wang, Gary C. Hon · 2024 · Frontiers in Genome Editing
52. An oncogenic enhancer promotes melanoma progression via regulating ETV4 expression
    Junyou Zhang, Qilin Wang, Sihan Qi, Yingying Duan, Zhaoshuo Liu, Jiaxin Liu, Ziyi Zhang, Chunyan Li · 2024 · Journal of Translational Medicine
53. Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis
    Rémi Terranova, Antonio Vitobello, Alberto Del Río-Espínola, C. Roland Wolf, Michael Schwarz, John M. Thomson, Richard R. Meehan, Jonathan G. Moggs · 2017 · Current Opinion in Toxicology
54. Centenarian Rates and Life Expectancy Related to the Death Rates of Multiple Sclerosis, Asthma, and Rheumatoid Arthritis and the Incidence of Type 1 Diabetes in Children
    Lilia S. Lens-Pechakova · 2015 · Rejuvenation Research
55. Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records
    Nima Pouladi, l. Achour, H. Li, Joanne Berghout, Colleen Kenost, Manuel L. Gonzalez‐Garay, Yves A. Lussier · 2016 · Yearbook of Medical Informatics
56. Detecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity
    Shan‐Shan Dong, Shi Yao, Yixiao Chen, Yan Guo, Yujie Zhang, Huimin Niu, Ruo-Han Hao, Hui Shen, Qing Tian, Hong‐Wen Deng et al. · 2018 · International Journal of Obesity
57. SEdb 3.0: a comprehensive super-enhancer database across multiple species
    Shuang Song, Liyuan Liu, Chenchen Feng, Liyuan Xie, Guorui Zhang, Yuexin Zhang, Yichen Gao, Mingxue Yin, Xiuyun Tang, Wenya Pei et al. · 2025 · Nucleic Acids Research
58. Enhancer/gene relationships: Need for more reliable genome-wide reference sets
    Tristan Hoellinger, Camille Mestre, Hugues Aschard, Wilfried Le Goff, Sylvain Foissac, Thomas Faraut, Sarah Djebali · 2023 · Frontiers in Bioinformatics
59. Rodent genetically modified models of glaucoma
    Yunhua Loo, Anita Sook Yee Chan, Chiea Chuen Khor, Tin Aung, Zhenxun Wang · 2023 · Molecular Aspects of Medicine
60. Analysis of the landscape of human enhancer sequences in biological databases
    Juan Mulero-Hernández, Jesualdo Tomás Fernández‐Breis · 2022 · Computational and Structural Biotechnology Journal
61. Local ancestry transitions modify snp-trait associations
    Alexandra E. Fish, Dana C. Crawford, John A. Capra, William S. Bush · 2017 · Pacific Symposium on Biocomputing (PSB)
62. Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential
    Janneke G. C. Peeters, Sebastiaan J. Vastert, Femke van Wijk, Jorg van Loosdregt · 2017 · Arthritis & Rheumatology
63. Autoimmunity-Associated SNP rs3024505 Disrupts STAT3 Binding in B Cells, Leading to IL10 Dysregulation
    Aksinya Nicolaevna Uvarova, Elina A. Zheremyan, Alina S. Ustiugova, Matvey Mikhailovich Murashko, Elvina A. Bogomolova, Д. Э. Демин, Ekaterina M. Stasevich, Dmitry V. Kuprash, Kirill V. Korneev · 2024 · International Journal of Molecular Sciences
64. A multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility
    Melissa Sorosina, Nadia Barizzone, Ferdinando Clarelli, Santosh Kumar Anand, Sara Lupoli, Erika Salvi, Eleonora Mangano, Roberta Bordoni, Tina Roostaei, Elisabetta Mascia et al. · 2022 · Journal of Neurology
65. Leveraging epigenomes and three-dimensional genome organization for interpreting regulatory variation
    Brittany A. Baur, Jacob Matthew Schreiber, Junha Shin, Shilu Zhang, Yi Zhang, Mohith Manjunath, Jun S. Song, William Stafford Noble, Sushmita Roy · 2023 · PLoS Computational Biology
66. HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer
    Ansley Gnanapragasam, Eftyhios Kirbizakis, Anna Li, Kyle H. White, Katelyn L. Mortenson, Juliana Cavalcante de Moura, Wajih Jawhar, Yifei Yan, Reilly Falter, Colleen S. Russett et al. · 2024 · Cancer Research
67. Recently Emerged Genome Wide Computational Enhancer Target Prediction Tools: A Brief Survey
    Leonard Whye Kit Lim · 2023 · International Journal of Zoology and Animal Biology
68. Novel association between a transient receptor potential cation channel subfamily M member 5 expression quantitative trait locus rs35197079 and decreased susceptibility of gestational diabetes mellitus in a Chinese population
    Xi Li, Liping Lai, Jindi Su, Shiguo Chen, Sheng Lin, Baojiang Wang, Jian Gao, Zhang Linghua, Keqin Yao, Shan Duan · 2021 · Journal of Diabetes Investigation
69. CRUP: A comprehensive framework to predict condition-specific regulatory units
    Anna Ramisch, Verena Heinrich, Laura V. Glaser, Alisa Fuchs, Xinyi Yang, Philipp Benner, Robert Schöpflin, Na Li, Sarah Kinkley, Anja Hillmann et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
70. Enhancer RNA LINC00242-Induced Expression of PHF10 Drives a Better Prognosis in Pancreatic Adenocarcinoma
    Wen Tong, Liuyang Zhu, Yi Bai, Long Yang, Zirong Liu, Yamin Zhang · 2022 · Frontiers in Oncology
71. Multivariate Bayesian variable selection for multi-trait genetic fine mapping
    Travis A. Canida, Hongjie Ke, Shuo Chen, Zhenyao Ye, Tianzhou Ma · 2024 · Journal of the Royal Statistical Society Series C (Applied Statistics)
72. Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain
    Adam E. Handel, Giuseppe Gallone, M. Zameel Cader, Chris P. Ponting · 2016 · Human Molecular Genetics
73. Integrative genomic analysis predicts novel functional enhancer-SNPs for bone mineral density
    Chuan Qiu, Hui Shen, Xiaoying Fu, Chao Xu, Qing Tian, Hong‐Wen Deng · 2019 · Human Genetics
74. Shaping the nebulous enhancer in the era of high-throughput assays and genome editing
    Edwin Yu-Kiu Ho, Qin Cao, Mengting Gu, Ricky Wai-Lun Chan, Qiong Wu, Mark Gerstein, Kevin Yuk-Lap Yip · 2019 · Briefings in Bioinformatics
75. Two distinct mechanisms underlie estrogen-receptor-negative breast cancer susceptibility at the 2p23.2 locus
    Gustavo Mendoza-Fandiño, Paulo Cilas Morais Lyra Junior, Thales C. Nepomuceno, Carly M. Harro, Nicholas T. Woods, Xueli Li, Letícia Batista Azevedo Rangel, Marcelo Alex Carvalho, Fergus J. Couch, Álvaro N.A. Monteiro · 2021 · European Journal of Human Genetics
76. Massively parallel reporter assays identify functional enhancer variants at QT interval GWAS loci
    Dongwon Lee, Lavanya Gunamalai, Jeerthi Kannan, Kyla Vickery, Or Yaacov, Ana C. Onuchic-Whitford, Aravinda Chakravarti, Ashish Kapoor · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
77. Functional characterization of ampd1 and its SNPs in the muscle IMP synthesis of hybrid bream (Megalobrama amblycephala ♀ × Culter alburnus ♂)
    Z. Z. Xu, Qinqin Xiao, Mingyu Zhang, Yimiao He, Qianting Zheng, Junchi Zhao, Anli Zuo, Jianzhou Tang, Yonghua Zhou, Shenping Cao et al. · 2025 · Aquaculture
78. Cellular network perturbations by disease-associated variants
    Jared Allan Sewell, Juan I. Fuxman Bass · 2017 · Current Opinion in Systems Biology
79. Methods of massive parallel reporter assays for investigation of enhancers
    Stanislav E. Romanov, Darya A. Kalashnikova, Petr P. Laktionov · 2021 · Vavilov Journal of Genetics and Breeding
80. A systematic study of motif pairs that may facilitate enhancer–promoter interactions
    Saidi Wang, Haiyan Hu, Xiaoman Li · 2022 · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics
81. Full-Length Transcript Phasing with Third-Generation Sequencing
    Nenad Svrzikapa, Ramakrishna Boyanapalli · 2022 · Methods in molecular biology
82. Integrating extrusion complex-associated pattern to predict cell type-specific long-range chromatin loops
    Yajing Deng, Li Tang, Xiaolong Zhou, Wenkang Wang, Min Li · 2022 · iScience
83. Computational methods for identifying enhancer‐promoter interactions
    Haiyan Gong, Zhengyuan Chen, Yuxin Tang, Minghong Li, Sichen Zhang, Xiaotong Zhang, Yang Chen · 2023 · Quantitative Biology
84. A Survey of the Computational Methods for Enhancers and Enhancer-target Predictions
    Qin Cao, Kevin Yuk-Lap Yip · 2016 · CRC Press eBooks
85. A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population
    Yi Zhang, Yan Li, Shaojie Jiang, Wei Chen, Jiao Lou, Juntao Ke, Jiaoyuan Li, Ying Zhu, Yajie Gong, Yang Yang et al. · 2016 · Oncotarget
86. A functional strategy to characterize expression Quantitative Trait Loci
    Elena Grassi, Elisa Mariella, Mattia Forneris, Federico Marotta, Marika Catapano, Ivan Molineris, Paolo Provero · 2017 · Human Genetics
87. Recognition of the long range enhancer-promoter interactions by further adding DNA structure properties and transcription factor binding motifs in human cell lines
    Zhenxing Feng, Qian‐Zhong Li, Jian-Jun Meng · 2018 · Journal of Theoretical Biology
88. An Approach for Recognition of Enhancer-promoter Associations based on Random Forest
    Tianjiao Zhang, Ya-Dong Wang · 2019 · International Conference on Biomedical Signal and Image Processing
89. An intriguing characteristic of enhancer-promoter interactions
    Amlan Talukder, Haiyan Hu, Xiaoman Li · 2021 · BMC Genomics
90. HyperCas12a enables multiplexed CRISPRi screens
    Schuyler M. Melore, Christian McRoberts Amador, Marisa C. Hamilton, Charles A. Gersbach, Timothy E. Reddy · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
91. FOXA1 of regulatory variant associated with risk of breast cancer through allele-specific enhancer in the Chinese population
    Bin Li, Xiang Chao Cheng, Ying Zhu, Hao Wan, Zequn Lu, Yimin Cai, Wenhui Li, Pengfei Yi, Li Liu, Jiang Chang et al. · 2021 · Breast Cancer
92. A multifaceted journey into higher-order chromatin organization: Insights from experimental and computational approaches
    Vikash Kumar Yadav, Siddhi Kashinath Jalmi · 2025 · International Journal of Biological Macromolecules
93. Molecular systems, human noncoding sequence variants, and blood pressure
    Qiongzi Qiu, Mingyu Liang · 2026 · Physiological Reviews
94. A functional ancestry-linked regulatory haplotype influences CYP2D6 expression
    Michael McCoy · 2026 · The Pharmacogenomics Journal
95. Functional characterization of QT interval associated SCN5A enhancer variants identify combined additive effects
    Lavanya Gunamalai, Parul Singh, Brian Berg, Leilei Shi, Ernesto Sanchez, Alexa Smith, Ghislaı̀n Breton, Mark T. Bedford, Darius Balciunas, Ashish Kapoor · 2024 · Human Genetics and Genomics Advances
96. PARGP1, a specific enhancer RNA associated with biochemical recurrence of prostate cancer
    Xiaojie Ang, Zekun Xu, Qi Zhou, Zhiyu Zhang, Lu Ma, Xi Zhang, Feng Zhou, Weiguo Chen · 2021 · All Life
97. Epigenetics, Enhancers, and Cancer
    James J. Morrow, Peter C. Scacheri · 2016 · Energy balance and cancer
98. Epigenetics: Chromatin Organization and Function
    Geneviève P. Delcuve, Dilshad H. Khan, Vichithra R. B. Liyanage, Sanzida Jahan, Mojgan Rastegar, Lorrie A. Kirshenbaum, James Davie · 2016 · Cardiac and vascular biology
99. Omics in Diabetic Kidney Disease
    Massimo Papale, Francesca Conserva, Paola Pontrelli, Loreto Gesualdo · 2018 · Springer eBooks
100. eQTL Mapping Using Transcription Factor Affinity
     Elisa Mariella, Elena Grassi, Paolo Provero · 2019 · Methods in molecular biology