Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

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Items 101–200 of 209

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    Heon Seok Kim, Gue‐Ho Hwang, Hyomin K. Lee, Taegeun Bae, Seong-Ho Park, Yong Jun Kim, Sun Lee, Jae-Hoon Park, Sangsu Bae, Junho K. Hur · 2021 · Molecular Therapy — Methods & Clinical Development
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    Maria Georgomanoli, Eirini P. Papapetrou · 2019 · Disease Models & Mechanisms
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    Pradeep Bompada, David Atac, Cheng Luan, Robin Andersson, Judit Domènech Omella, Emilia Ottosson-Laakso, Jason B. Wright, Leif Groop, Yang Z. De Marinis · 2016 · The International Journal of Biochemistry & Cell Biology
  9. Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones
    Richard H. Smith, Yun-Ching Chen, Fayaz Seifuddin, Daniel N. Hupalo, Camille Alba, Robert N. Reger, Xin Tian, Daisuke Araki, Clifton L. Dalgard, Richard W. Childs et al. · 2020 · Genes
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  11. Prime editing: current advances and therapeutic opportunities in human diseases
    Yidian Fu, Xiaoyu He, Xin D. Gao, Fang Li, Shengfang Ge, Zhi Hua Yang, Xianqun Fan · 2023 · 中国科学通报:英文版
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  15. Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling
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  18. Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion Neurons
    Yuxi Chen, Shengyao Zhi, Puping Liang, Qi Zheng, Mengni Liu, Qi Zhao, Jian Min Ren, Jun Cui, Junjiu Huang, Yizhi Liu et al. · 2020 · Molecular Therapy — Methods & Clinical Development
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  23. Data Mining by Pluralistic Approach on CRISPR Gene Editing in Plants
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  27. Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
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  34. Insights into Prime Editing Technology: A Deep Dive into Fundamentals, Potentials, and Challenges
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  36. An overview of currently available molecular Cas-tools for precise genome modification
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  37. VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9
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  38. Comprehensive Analysis of CRISPR/Cas9-Mediated Mutagenesis in Arabidopsis thaliana by Genome-Wide Sequencing
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  40. Utilization of CRISPR/Cas9 gene editing in cellular therapies for lymphoid malignancies
    Maryam Mehravar, Elham Roshandel, Maryam Salimi, Rouzbeh Chegeni, Majid Gholizadeh, Mohammad Hossein Mohammadi, Abbas Hajifathali · 2020 · Immunology Letters
  41. Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome Manipulation
    Aino Vesikansa · 2018 · Journal of Central Nervous System Disease
  42. Immortalization of primary marmoset skin fibroblasts by CRISPR-Cas9-mediated gene targeting
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  44. SeqCor: correct the effect of guide RNA sequences in clustered regularly interspaced short palindromic repeats/Cas9 screening by machine learning algorithm
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  45. Methods for detecting off-target effects of CRISPR/Cas9
    Yingying Xu, Shengmei Zhou, Lu-Yan Wang, Rong Zhang, Kai Li, Zhiyuan Qian, Xiao Li · 2025 · Biotechnology Advances
  46. Generating CRISPR‐Cas9‐Mediated Null Mutations and Screening Targeting Efficiency in Human Pluripotent Stem Cells
    Oliver J. Bower, Afshan McCarthy, Rebecca A. Lea, Gregorio Alanis‐Lobato, Jasmin Zohren, Claudia Gerri, James M. A. Turner, Kathy K. Niakan · 2021 · Current Protocols
  47. Genome-wide CRISPR off-target DNA break detection by the BLISS method
    Ballarino, Roberto, Bouwman, Britta A. M., Crosetto, Nicola · 2021 · Methods in molecular biology
  48. Gene Editing for Enhanced Swine Production: Current Advances and Prospects
    Won Seok Ju, Seokho Kim, Jae-Yeong Lee, Haesun Lee, Jin-Gu No, Seunghoon Lee, Keon Bong Oh · 2025 · Animals
  49. Challenges and Future Prospects of CRISPR Technology
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  50. Effect of the Phosphoryl Guanidine Modification in Chimeric DNA–RNA crRNAs on the Activity of the CRISPR-Cas9 System In Vitro
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  51. A comprehensive review on the current status of CRISPR based clinical trials for rare diseases
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  53. A Review: Computational Approaches to Design sgRNA of CRISPR-Cas9
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  54. Crispr2vec: Machine Learning Model Predicts Off-Target Cuts of CRISPR systems
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  55. Detailed mechanisms for unintended large DNA deletions with CRISPR, base editors, and prime editors
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  56. Engineered Sdd7 cytosine base editors with enhanced specificity
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  100. Additional file 1 of Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches
    Jeonghun Kwon, Kim, Minyoung, Hwang, Woochang, Anna Jo, Hwang, Gue-Ho, Jung, Minhee, Kim, Un Gi, Gang Cui, Heon Seok Kim, Eom, Joon-Ho et al. · 2023 · Figshare