Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
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Items 101–200 of 209
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- Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and miceJin-Jing Li, Xiang Lin, Cheng Tang, Ying‐Qian Lu, Xinde Hu, Erwei Zuo, He Li, Wenqin Ying, Yidi Sun, Lu‐Lu Lai et al. · 2019 · National Science Review
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- Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell ClonesRichard H. Smith, Yun-Ching Chen, Fayaz Seifuddin, Daniel N. Hupalo, Camille Alba, Robert N. Reger, Xin Tian, Daisuke Araki, Clifton L. Dalgard, Richard W. Childs et al. · 2020 · Genes
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- Prime editing: current advances and therapeutic opportunities in human diseasesYidian Fu, Xiaoyu He, Xin D. Gao, Fang Li, Shengfang Ge, Zhi Hua Yang, Xianqun Fan · 2023 · 中国科学通报:英文版
- Therapeutic applications of CRISPR RNA-guided genome editingTaeyoung Koo, Jin‐Soo Kim · 2016 · Briefings in Functional Genomics
- Extru-seq: A method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approachesKwon, Jeonghun, Kim, Minyoung, Hwang, Woochang, Jo, Anna, Hwang, Gue-Ho, Jung, Minhee, Kim, Un Gi, Cui, Gang, Kim, Heonseok, Eom, Joon-Ho et al. · 2023 · Genome biology
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- Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profilingYonggang Zhang, Gustavo Arango, Fang Li, Xiao Xiao, Raj Putatunda, Jun Yu, Xiao Feng Yang, Hong Wang, Layne T. Watson, Liqing Zhang et al. · 2018 · BMC Medical Genomics
- Engineering of Cas12a nuclease variants with enhanced genome-editing specificityPeng Chen, Jin Zhou, Huan Liu, Er-Chi Zhou, Boxiao He, Yankang Wu, Hongjian Wang, Zaiqiao Sun, Chonil Paek, Jun Lei et al. · 2024 · PLoS Biology
- The application of CRISPR-Cas9 genome editing tool in cancer immunotherapyHongyan Wu, Chunyu Cao · 2018 · Briefings in Functional Genomics
- Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion NeuronsYuxi Chen, Shengyao Zhi, Puping Liang, Qi Zheng, Mengni Liu, Qi Zhao, Jian Min Ren, Jun Cui, Junjiu Huang, Yizhi Liu et al. · 2020 · Molecular Therapy — Methods & Clinical Development
- An unbiased method for evaluating the genome-wide specificity of base editors in riceShuai Jin, Qiang Gao, Caixia Gao · 2020 · Nature Protocols
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- Data Mining by Pluralistic Approach on CRISPR Gene Editing in PlantsTanushri Kaul, Nitya Meenakshi Raman, Murugesh Eswaran, Arulprakash Thangaraj, Rachana Verma, Sonia Khan Sony, Krishnamurthy Sathelly, Rashmi Kaul, Pranjal Yadava, Pawan Kumar Agrawal · 2019 · Frontiers in Plant Science
- CRISPR genome engineering for retinal diseasesAriel Kantor, Michelle E. McClements, Caroline F. Peddle, Lewis E. Fry, Ahmed Salman, Jasmina Cehajic‐Kapetanovic, Kanmin Xue, Robert Edward MacLaren · 2021 · Progress in molecular biology and translational science
- CRISPR to the Rescue: Advances in Gene Editing for the FMR1 GeneCarolyn M. Yrigollen, Beverly L. Davidson · 2019 · Brain Sciences
- Editing human hematopoietic stem cells: advances and challengesSenthil Velan Bhoopalan, Jonathan S. Yen, Rachel M. Levine, Akshay Sharma · 2022 · Cytotherapy
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- Advancing fish disease research through CRISPR-Cas genome editing: Recent developments and future perspectivesHuria Marnis, Khairul Syahputra · 2025 · Fish & Shellfish Immunology
- Chemical Modification and Transformation Strategies of Guide RNAs in CRISPR‐Cas9 Gene Editing SystemsYu Zhang, Qian Wang, Jing Wang, Xinjing Tang · 2021 · ChemPlusChem
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- Insights into Prime Editing Technology: A Deep Dive into Fundamentals, Potentials, and ChallengesSeyed Younes Hosseini, Rahul Mallick, Petri Mäkinen, Seppo Ylä‐Herttuala · 2024 · Human Gene Therapy
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- An overview of currently available molecular Cas-tools for precise genome modificationEkaterina V. Kondrateva, Anna G. Demchenko, А. В. Лавров, Svetlana Smirnikhina · 2020 · Gene
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- Utilization of CRISPR/Cas9 gene editing in cellular therapies for lymphoid malignanciesMaryam Mehravar, Elham Roshandel, Maryam Salimi, Rouzbeh Chegeni, Majid Gholizadeh, Mohammad Hossein Mohammadi, Abbas Hajifathali · 2020 · Immunology Letters
- Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome ManipulationAino Vesikansa · 2018 · Journal of Central Nervous System Disease
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- Gene Editing for Enhanced Swine Production: Current Advances and ProspectsWon Seok Ju, Seokho Kim, Jae-Yeong Lee, Haesun Lee, Jin-Gu No, Seunghoon Lee, Keon Bong Oh · 2025 · Animals
- Challenges and Future Prospects of CRISPR TechnologyZulqurnain Khan, Sultan Habibullah Khan, Aftab Ahmad · 2021 · Springer eBooks
- Effect of the Phosphoryl Guanidine Modification in Chimeric DNA–RNA crRNAs on the Activity of the CRISPR-Cas9 System In VitroDaria V. Prokhorova, Maxim S. Kupryushkin, Sergey A. Zhukov, Timofey D. Zharkov, Ilya S. Dovydenko, Kristina I. Yakovleva, Ivan M. Pereverzev, Anastasiya M. Matveeva, Dmitrii V. Pyshnyi, Grigory A. Stepanov · 2024 · ACS Chemical Biology
- A comprehensive review on the current status of CRISPR based clinical trials for rare diseasesAmneet Kaur Badwal, Sushma Singh · 2024 · International Journal of Biological Macromolecules
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