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A comprehensive map of the porcine genome.

Open access
Rohrer, G A, Alexander, L J, Hu, Z, Smith, T P, Keele, J W, Beattie, C W·1996·Genome Research

Abstract

We report the highest density genetic linkage map for a livestock species produced to date. Three published maps for Sus scrofa were merged by genotyping virtually every publicly available microsatellite across a single reference population to yield 1042 linked loci, 536 of which are novel assignments, spanning 2286.2 cM (average interval 2.23 cM) in 19 linkage groups (18 autosomal and X chromosomes, n = 19). Linkage groups were constructed de novo and mapped by locus content to avoid propagation of errors in older genotypes. The physical and genetic maps were integrated with 123 informative loci assigned previously by fluorescence in situ hybridization (FISH). Fourteen linkage groups span the entire length of each chromosome. Coverage of chromosomes 11, 12, 15, and 18 will be evaluated as more markers are physically assigned. Marker-deficient regions were identified only on 11q1.7-qter and 14 cen-q1.2. Recombination rates (cM/Mbp) varied between and within chromosomes. Short chromosomal arms recombined at higher rates than long arms, and recombination was more frequent in telomeric regions than in pericentric regions. The high-resolution comprehensive map has the marker density needed to identify quantitative trait loci (QTL), implement marker-assisted selection or introgression and YAC contig construction or chromosomal microdissection.

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Metadata

Authors
Rohrer, G. A., Alexander, L. J., Hu, Z., Smith, T. P., Keele, J. W., & Beattie, C. W.
Venue
Genome Research
Published
1996-05
Volume
6
Issue
5
Pages
371-391
ISSN
1088-9051 (ISSN-L)
OpenAlex
W2117070324
Cited by
475
References
0
Type
posted content
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A comprehensive map of the porcine genome. https://app.cochat.ai/papers/10.1101/gr.6.5.371
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Rohrer, G. A., Alexander, L. J., Hu, Z., Smith, T. P., Keele, J. W., & Beattie, C. W. (1996). A comprehensive map of the porcine genome. Genome Research. https://doi.org/10.1101/gr.6.5.371

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