ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons
Alonso, Mariana, Medina, Jorge H., Pozzo-Miller, Lucas·2004·Learning & Memory
DOI 10.1101/lm.67804
Cited by (411)
Items 201–300 of 411
- A role for MAPK and PI-3K signaling pathways in brain-derived neurotrophic factor modification of conditioned taste aversion retentionDiana V. Castillo, Martha Lilia Escobar · 2010 · Behavioural Brain Research
- Mixture of Peanut Skin Extract and Fish Oil Improves Memory in Mice via Modulation of Anti-Oxidative Stress and Regulation of BDNF/ERK/CREB Signaling PathwaysLan Xiang, Xueli Cao, Tian-Yan Xing, Daisuke Mori, Ruiqi Tang, Jing Li, Lijuan Gao, Jianhua Qi · 2016 · Nutrients
- Cell type-specific effects of BDNF in modulating dendritic architecture of hippocampal neuronsMarta Zagrebelsky, Nina Gödecke, Anita Remus, Martin Körte · 2018 · Brain Structure and Function
- Temperature- and chemical-induced neurotoxicity in zebrafishMattia Toni, Chiara Arena, Carla Cioni, Gabriella Tedeschi · 2023 · Frontiers in Physiology
- Effects of adropin on learning and memory in rats tested in the Morris water mazeAyse Ozkan, M. Aslan, Osman Sinen, Mustafa Munzuroğlu, N. Derin, H. Parlak, M. Bulbul, A. Agar · 2021 · Hippocampus
- n−3 fatty acids prevent impairment of neurogenesis and synaptic plasticity in B-cell activating factor (BAFF) transgenic miceRosalia Crupi, Marco Cambiaghi, Richard Joseph Deckelbaum, Inge Berg Hansen, Janet Mindes, Edoardo Spina, Fortunato Battaglia · 2011 · Preventive Medicine
- Brain‐derived neurotrophic factor produced by human umbilical tissue‐derived cells is required for its effect on hippocampal dendritic differentiationJanet Alder, Brian C. Kramer, Casey Hoskin, Smita Thakker‐Varia · 2011 · Developmental Neurobiology
- A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's diseaseJoão Fonseca‐Gomes, Tiago Costa-Coelho, Mafalda Ferreira-Manso, Sara Inteiro-Oliveira, Sandra Henriques Vaz, Nuno Alemãn-Serrano, Henrique Atalaia-Barbacena, Leonor Ribeiro‐Rodrigues, Rita M. Ramalho, Rui Resende Pinto et al. · 2024 · Molecular Therapy
- Furin promotes dendritic morphogenesis and learning and memory in transgenic miceBinglin Zhu, Lige Zhao, Dong Luo, Demei Xu, Tao Tan, Zhifang Dong, Ying Tang, Zhuo Min, Xiaojuan Deng, Fei Sun et al. · 2018 · Cellular and Molecular Life Sciences
- Protective Effects of Cornel Iridoid Glycoside in Rats After Traumatic Brain InjuryDenglei Ma, Na Wang, Xiaotong Fan, Lan Zhang, Yi Luo, Rui Huang, Li Zhang, Yali Li, Guoguang Zhao, Lin Li · 2018 · Neurochemical Research
- Investigating the Role of BDNF in Insomnia: Current InsightsMarta Ditmer, Agata Gabryelska, Szymon Turkiewicz, Marcin Sochal · 2023 · Nature and Science of Sleep
- Long term alterations in synaptic physiology, expression of β2 nicotinic receptors and ERK1/2 signaling in the hippocampus of rats with prenatal nicotine exposureKodeeswaran Parameshwaran, Manal Ali Buabeid, Subhrajit Bhattacharya, Subramaniam Uthayathas, Thiruchelvam Kariharan, Muralikrishnan Dhanasekaran, Vishnu D. Suppiramaniam · 2013 · Neurobiology of Learning and Memory
- Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat ModelMyoung‐Ae Choe, Byung‐Soo Koo, Gyeong Ju An, Songhee Jeon · 2012 · Korean Journal of Physiology and Pharmacology
- BDNF genotype is associated with hippocampal volume in mild traumatic brain injuryJasmeet Pannu Hayes, A. Reagan, Mark W. Logue, Scott M. Hayes, Naomi Sadeh, Danielle R. Miller, Mieke H. Verfaellie, Erika J. Wolf, Regina E. McGlinchey, William Milberg et al. · 2017 · Genes Brain & Behavior
- Memory Impairment Induced by Borna Disease Virus 1 Infection is Associated with Reduced H3K9 AcetylationJie Jie, Xiaoyan Xu, Jinjun Xia, Zhe Tu, Yujie Guo, Chenmeng Li, Xiong Zhang, Haiyang Wang, Weihong Song, Peng Xie · 2018 · Cellular Physiology and Biochemistry
- Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 MiceFoteini Vasilopoulou, Aina Bellver‐Sanchís, Júlia Companys‐Alemany, Júlia Jarné‐Ferrer, Alba Irisarri, Verónica Palomera‐Ávalos, Célia González-Castillo, Daniel Ortuño‐Sahagún, Coral Sanfeliu, Mercè Pallàs et al. · 2022 · Cells
- Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neuronsTatiana Adasme, Andrea Cristina Paula-Lima, Cecilia Hidalgo · 2015 · Biochemical and Biophysical Research Communications
- Factoring neurotrophins into a neurite-based pathophysiological model of schizophreniaAlfredo Bellon, Marie‐Odile Krebs, Thérèse M. Jay · 2011 · Progress in Neurobiology
- Signaling via Dopamine D1 and D3 Receptors Oppositely Regulates Cocaine-Induced Structural Remodeling of Dendrites and SpinesLei Zhang, Juan Li, Nuyun Liu, Bin Wang, Jingjing Gu, Min Zhang, Zhitao Zhou, Yong Mei Jiang, Lin Zhang, Lu Zhang · 2011 · Neurosignals
- Microinjection of histone deacetylase inhibitor into the ventrolateral orbital cortex potentiates morphine induced behavioral sensitizationLai Wei, Yuan-Mei Zhu, Yuxiang Zhang, Feng Liang, Devin M. Barry, Hong-Yu Gao, Tao Li, Fu‐Quan Huo, Chunxia Yan · 2016 · Brain Research
- Insulin‐regulated aminopeptidase inhibitor‐mediated increases in dendritic spine density are facilitated by glucose uptakeBenjamin Seyer, Shanti Diwakarla, Peta L. Burns, Anders Hallberg, Alfhild Grönbladh, Mathias Hallberg, Siew Yeen Chai · 2019 · Journal of Neurochemistry
- The effect of Melissa officinalis L. extract on learning and memory: Involvement of hippocampal expression of nitric oxide synthase and brain-derived neurotrophic factor in diabetic ratsMohsen Naseri, Reza Arabi Mianroodi, Zeynab Pakzad, Peyman Falahati, Masomeh Borbor, Hossein Azizi, Sima Nasri · 2021 · Journal of Ethnopharmacology
- Co-treatment of vitamin D supplementation with enriched environment improves synaptic plasticity and spatial learning and memory in aged ratsMahnaz Bayat, Kristi A. Kohlmeier, Masoud Haghani, Afshin Borhani‐Haghighi, Azadeh Khalili, Gholamreza Bayat, Etrat Hooshmandi, Mohammad Shabani · 2021 · Psychopharmacology
- Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal NeuronsSoledad Ferreras, Guillermo Fernández, Víctor Danelon, María V. Pisano, Luján Masseroni, Christopher A. Chapleau, Favio Ariel Krapacher, Estela Cecilia Mlewski, Daniel Hugo Mascó, Carlos Arias et al. · 2017 · Frontiers in Cellular Neuroscience
- Hydrophilic Glycoproteins of an Edible Green Alga Capsosiphon fulvescens Prevent Aging-Induced Spatial Memory Impairment by Suppressing GSK-3β-Mediated ER Stress in Dorsal HippocampusJeong Hwan Oh, Taek‐Jeong Nam · 2019 · Marine Drugs
- A simple DMSO-based method for cryopreservation of primary hippocampal and cortical neuronsYuta Ishizuka, Clive R. Bramham · 2019 · Journal of Neuroscience Methods
- Enhanced Ras activity promotes spine formation in synRas mice neocortexUlrich G??rtner, Al??n Alp??r, Julia Behrbohm, Rolf Heumann, Thomas Arendt · 2005 · Neuroreport
- Prolonged ampakine exposure prunes dendritic spines and increases presynaptic release probability for enhanced long‐term potentiation in the hippocampusPhilip K.‐Y. Chang, George Amadeus Prenosil, David Verbich, Raminder Gill, Rebecca Anne McKinney · 2014 · European Journal of Neuroscience
- The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor DysbindinMiranda Arnold, Rebecca Cross, Kaela S. Singleton, Stephanie A. Zlatic, Christopher A. Chapleau, Ariana P. Mullin, Isaiah J. Rolle, Carlene C. Moore, Anne B. Theibert, Lucas D. Pozzo‐Miller et al. · 2016 · Frontiers in Cellular Neuroscience
- Regulation of fear extinction by long-term depression: The roles of endocannabinoids and brain derived neurotrophic factorMaxwell R. Bennett, Jonathon Carl Arnold, Sean N. Hatton, Jim Lagopoulos · 2016 · Behavioural Brain Research
- Platycodon grandiflorus Root Extract Improves Learning and Memory by Enhancing Synaptogenesis in Mice HippocampusJin-Il Kim, Seong Gak Jeon, Kyoung Kim, Jwa-Jin Kim, Eun Song, Yukyoung Jeon, Eunbin Kim, Kyung Lee, Jong Hwan Kwak, Minho Moon · 2017 · Nutrients
- Scabronine G Methyl Ester Improves Memory-Related Behavior and Enhances Hippocampal Cell Proliferation and Long-Term Potentiation via the BDNF-CREB Pathway in Olfactory Bulbectomized MiceOsamu Nakagawasai, Jia-Rong Lin, Takayo Odaira, Kohei Takahashi, Wataru Nemoto, Shigeki Moriguchi, Yasushi Yabuki, Yu Kobayakawa, Kohji Fukunaga, Masahisa Nakada et al. · 2020 · Frontiers in Pharmacology
- Doxycycline at subantimicrobial dose combined with escitalopram reverses depressive-like behavior and neuroinflammatory hippocampal alterations in the lipopolysaccharide model of depressionBruna Stefânia Ferreira Mello, Adriano José Maia Chaves Filho, Charllyany Sabino Custódio, Patrícia de Araújo Rodrigues, Jaqueline Vieira Carletti, Silvânia Maria Mendes Vasconcelos, Francisca Cléa Florenço de Sousa, Lia Lira Olivier Sanders, Danielle S. Macêdo · 2021 · Journal of Affective Disorders
- Synaptic Functions of Invertebrate Varicosities: What Molecular Mechanisms Lie BeneathCarlo NG Giachello, Pier Giorgio Montarolo, Mirella Ghirardi · 2012 · Neural Plasticity
- Region-Dependent Alterations in Cognitive Function and ERK1/2 Signaling in the PFC in Rats after Social Defeat StressQiong Wang, Feng Shao, Weiwen Wang · 2018 · Neural Plasticity
- Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficitsAhmad Hamad Alhowail, Priyanka D. Pinky, Matthew Eggert, Jenna Bloemer, Lauren N. Woodie, Manal Ali Buabeid, Subhrajit Bhattacharya, Shanese L. Jasper, Dwipayan Bhattacharya, Muralikrishnan Dhanasekaran et al. · 2021 · Heliyon
- Memory consolidation impairment induced by Interleukin-1β is associated with changes in hippocampal structural plasticityGuadalupe Herrera, Gastón Diego Calfa, Helgi B. Schiöth, Mercedes Lasaga, Teresa Nieves Scimonelli · 2019 · Behavioural Brain Research
- Local mRNA translation and cytoskeletal reorganization: Mechanisms that tune neuronal responsesNikoletta Triantopoulou, Marina Vidaki · 2022 · Frontiers in Molecular Neuroscience
- Maternal care associates with differences in morphological complexity in the medial preoptic areaCarine I. Parent, Xianglan Wen, Sabine K. Dhir, Richard Ryan, Josie C. Diorio, Tieyuan Zhang · 2017 · Behavioural Brain Research
- Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 UpregulationAtsuko Hayata‐Takano, Toshihiko Kamo, Harui Kijima, Kaoru Seiriki, Katsuya Ogata, Yukio Ago, Takanobu Nakazawa, Yusuke Shintani, Kosuke Higashino, Kazuki Nagayasu et al. · 2019 · Journal of Neuroscience
- BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neuronsLucas D. Pozzo‐Miller · 2006 · Brain Research
- Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in HippocampusMal-Soon Shin, Tae-Woon Kim, Sang-Seo Park, Il‐Gyu Ko, Chang‐Ju Kim, Mia Kim, Su-Yeon Roh, Kwang Taek Kim, Khae Hawn Kim · 2019 · International Neurourology Journal
- Neuropeptide orphanin FQ inhibits dendritic morphogenesis through activation of RhoAJanet Alder, Seth Kallman, Alicia J. Palmieri, Farah Khadim, Jennifer Ayer, Sujata Kumar, Katherine Tsung, Ilya Grinberg, Smita Thakker‐Varia · 2013 · Developmental Neurobiology
- Danggui-Jakyak-San enhances hippocampal long-term potentiation through the ERK/CREB/BDNF cascadeJee Hyun Yi, Hye Jin Park, Soo Ji Beak, Seungheon Lee, Ji Wook Jung, Byeong Chae Kim, Jong Hoon Ryu, Dong Hyun Kim · 2015 · Journal of Ethnopharmacology
- Interaction between electrical modulation of the brain and pharmacotherapy to control pharmacoresistant epilepsyLuísa Rocha · 2013 · Pharmacology & Therapeutics
- Simulated vehicle exhaust exposure induces sex-dependent behavioral deficits in ratsCamila Kochi, Ankita Salvi, Fatin Atrooz, Samina Salim · 2021 · Environmental Toxicology and Pharmacology
- Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activationC.J. Lee, Yi–Ju Chen, Han-Fang Wu, Yueh-Jung Chung, Yi‐Chao Lee, Cheng‐Ta Li, Hui‐Ching Lin · 2019 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Infralimbic BDNF signaling is necessary for the beneficial effects of extinction on set shifting in stressed ratsDenisse Paredes, Anna R. Knippenberg, David A. Morilak · 2021 · Neuropsychopharmacology
- Spatial Transcriptomics as a Novel Approach to Redefine Electrical Stimulation SafetyQuentin A. Whitsitt, Beomseo Koo, Mahmut Emin Çelik, Blake M. Evans, James David Weiland, Erin K. Purcell · 2022 · Frontiers in Neuroscience
- Testosterone modulation of dendritic spines of somatosensory cortical pyramidal neuronsJeng‐Rung Chen, Tsyr‐Jiuan Wang, Seh-Hong Lim, Yueh‐Jan Wang, Guo‐Fang Tseng · 2013 · Brain Structure and Function
- Fading memories in aging and neurodegeneration: Is p75 neurotrophin receptor a culprit?Lik‐Wei Wong, Zijun Wang, Sheila Rui Xia Ang, Sreedharan Sajikumar · 2022 · Ageing Research Reviews
- Understanding the Neuroplastic Effects of Auricular Vagus Nerve Stimulation in Animal Models of Stroke: A Systematic Review and Meta-AnalysisPaulo Sampaio de Melo, João Parente, Ingrid Rebello‐Sanchez, Anna Marduy, Anna Carolyna Gianlorenço, Chi Kyung Kim, Sung‐Hyuk Choi, Jae‐Jun Song, Felipe Fregni · 2023 · Neurorehabilitation and neural repair
- Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neuronsSvitlana V. Bach, Allison J. Bauman, Darya Hosein, Jennifer J. Tuscher, Lara Ianov, Kelsey M. Greathouse, Benjamin W. Henderson, Jeremy H. Herskowitz, Keri Martinowich, Jeremy J. Day · 2024 · Hippocampus
- Cellular and Molecular Mechanisms of REM Sleep Homeostatic Drive: A Plausible Component for Behavioral PlasticitySubimal Datta, Michael D. Oliver · 2017 · Frontiers in Neural Circuits
- Potent block of potassium channels by MEK inhibitor U0126 in primary cultures and brain slicesJinzhao Wang, Cheng Long, Kaiyuan Li, Huatai Xu, Li‐Lian Yuan, Gangyi Wu · 2018 · Scientific Reports
- Effects of Eugenol on Memory Performance, Neurogenesis, and Dendritic Complexity of Neurons in Mice Analyzed by Behavioral Tests and Golgi Staining of Brain TissueLatiful Akbar, Berry Juliandi, Arief Boediono, Irmanida Batubara, Mawar Subangkit · 2021 · Journal of Stem Cells and Regenerative Medicine
- BDNF Signaling in Glutamatergic Neurons During Long-Term Potentiation (LTP): A Spatio-Temporal Exploration of EventsKrishnakumar Mohandas, Rishikesh Rishikesh, Yadukrishnan Moothedath Balan, Ayswaria Deepti, Shirin Hosseini, Martin Körte, Baby Chakrapani Pulikaparambil Sasidharan · 2025 · Molecular Neurobiology
- Ndufs4 ablation decreases synaptophysin expression in hippocampusSubrata Kumar Shil, Yoshiteru Kagawa, Banlanjo Abdulaziz Umaru, Fumika Nanto-Hara, Hirofumi Miyazaki, Yui Yamamoto, Shuhei Kobayashi, Chitose Suzuki, Takaaki Abe, Yuji Owada · 2021 · Scientific Reports
- Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis modelJason A. Weesner, Ida Annunziata, Diantha van de Vlekkert, Camenzind G. Robinson, Yvan Campos, Ashutosh Mishra, Leigh E. Fremuth, Elida M. Gomero, Huimin Hu, Alessandra d’Azzo · 2024 · Cell Reports
- Synaptic maturation of the Xenopus retinotectal system: Effects of brain‐derived neurotrophic factor on synapse ultrastructureAngeliki Maria Nikolakopoulou, Margarita M. Meynard, Sonya Marshak, Susana Cohen‐Cory · 2009 · The Journal of Comparative Neurology
- The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease PathophysiologyRita F. Belo, Margarida L.F. Martins, Liana Shvachiy, Tiago Costa-Coelho, Carolina de Almeida-Borlido, João Fonseca‐Gomes, Vera Neves, Hugo Vicente Miranda, Tiago F. Outeiro, Joana Esteves Coelho et al. · 2020 · Frontiers in Pharmacology
- Inhibition of Elevated Ras-MAPK Signaling Normalizes Enhanced Motor Learning and Excessive Clustered Dendritic Spine Stabilization in the MECP2-Duplication Syndrome Mouse Model of AutismRyan Thomas Ash, Shelly Alexandra Buffington, Jiyoung Park, Bernhard Suter, Mauro Costa‐Mattioli, Huda Yahya Zoghbi, Stelios M. Smirnakis · 2021 · eNeuro
- Repetitive magnetic stimulation induces plasticity of excitatory synapses through cooperative pre- and postsynaptic activityChristos Galanis, Nicholas Hananeia, Maximilian Lenz, Mohammadreza Vasheghani Farahani, Peter Jedlička, Andreas Vlachos · 2025 · Brain stimulation
- Effects of Hibiscus sabdariffa calyces on spatial memory and hippocampal expression of BDNF in ovariectomized ratsGerardo Lorenzana-Martínez, Anne Santerre, Isaac Andrade‐González, Jacinto Bañuelos‐Pineda · 2020 · Nutritional Neuroscience
- Endocannabinoids and aging—Inflammation, neuroplasticity, mood and painYongsoon Park, Bruce A. Watkins · 2021 · Vitamins and hormones
- Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturationJun-Young Oh, Sangmyung Rhee, Alcino J. Silva, Yong‐Seok Lee, Hyong Kyu Kim · 2017 · Neuroscience Letters
- Spatial learning associated with stimulus response in goldfish Carassius auratus: relationship to activation of CREB signallingKoilmani Emmanuvel Rajan, Subramanian Thangaleela, Chellam Balasundaram · 2015 · Fish Physiology and Biochemistry
- High frequency stimulation of the infralimbic cortex induces morphological changes in rat hippocampal neuronsYarema B. Bezchlibnyk, Scellig S. D. Stone, Clement Hamani, Andrés M. Lozano · 2016 · Brain stimulation
- Energy sensors in drug addiction: A potential therapeutic targetAntonio J. López-Gambero, Fernando Rodrı́guez de Fonseca, Juan Suárez · 2020 · Addiction Biology
- Activity-Dependent Structural Plasticity of Dendritic SpinesChristopher A. Chapleau, Lucas D. Pozzo‐Miller · 2008 · Elsevier eBooks
- BDNF and its Role in the Alcohol Abuse Initiated During Early Adolescence: Evidence from Preclinical and Clinical StudiesDebora Cutuli, Piquero Sampedro-Piquero · 2022 · Current Neuropharmacology
- Central Stimulatory Effect of Kynurenic Acid on BDNF-TrkB Signaling and BER Enzymatic Activity in the Hippocampal CA1 Field in SheepKATARZYNA I. ROSZKOWICZ-OSTROWSKA, Patrycja Młotkowska, Paweł Kowalczyk, Elżbieta Marciniak, Marcin Barszcz, Tomasz Misztal · 2022 · International Journal of Molecular Sciences
- Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASDSeong Mi Lee, Yura Choi, Dayeon Kim, Ha Jin Jeong, Young Ho Do, Sohee Jung, Bomee Lee, Hyung Kyoon Choi, Suhyeon Kim, Jung‐Min Oh et al. · 2025 · Translational Psychiatry
- Light-induced changes in the suprachiasmatic nucleus transcriptome regulated by the ERK/MAPK pathwayDiego Alzate‐Correa, Sydney Aten, Moray J. Campbell, Kari R. Hoyt, Karl H. Obrietan · 2021 · PLoS ONE
- Hippocampal neurotrophins after stimulation of the basolateral amygdala, and memory improvement in lesioned ratsDaymara Mercerón‐Martínez, William Almaguer‐Melian, Teresa Serrano, Lourdes Lorigados, Nancy Pavón Fuentes, Jorge A. Bergado · 2013 · Restorative Neurology and Neuroscience
- Caloric restriction, physical activity, and cognitive performance: A review of evidence and a discussion of the potential mediators of BDNF and TrkBAlexis B. Slutsky, Jennifer L. Etnier · 2016 · International Journal of Sport and Exercise Psychology
- BDNF as a Putative Target for Standardized Extract of Ginkgo biloba-Induced Persistence of Object Recognition MemoryB. G. Muratori, Cláudia R. Zamberlam, T. B. Mendes, B. Nozima, J. Cerutti, S. M. Cerutti · 2021 · Molecules
- The autism risk gene CNTN4 modulates dendritic spine formationRongjuan Zhao, Tengfei Zhu, Qiong Liu, Qi Tian, Meng Wang, Jingjing Chen, Dali Tong, Bin Yu, Hui Guo, Kun Xia et al. · 2021 · Human Molecular Genetics
- Ras Inhibitor Lonafarnib Rescues Structural and Functional Impairments of Synapses of Aβ1-42 Mice via α7nAChR-Dependent BDNF UpregulationChengyun Cai, Lifeng Wang, Shixin Li, Sheng-Chun Lou, Jialie Luo, Ding‐Yi Fu, Tingting Chen · 2022 · Journal of Neuroscience
- A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome miceDestynie Medeiros, Karen Ayala-Baylon, Hailey X. Egido‐Betancourt, Eric C. Miller, Christopher A. Chapleau, Holly Robinson, Mary L. Phillips, Tao Yang, Frank M. Longo, Wei Li et al. · 2024 · Disease Models & Mechanisms
- G-protein-coupled receptor kinase interactor-1 serine 419 accelerates premature synapse formation in cortical neurons by interacting with Ca(2+)/calmodulin-dependent protein kinase IIβZitao Zhang, Wei Zhou, Jin Fan, Yongxin Ren, Guoyong Yin · 2013 · Brain Research Bulletin
- The BDNF val-66-met Polymorphism Affects Neuronal Morphology and Synaptic Transmission in Cultured Hippocampal Neurons from Rett Syndrome MiceXin Xu, Jordi Mir García, Rachel Ewalt, Shelly R. Nason, Lucas D. Pozzo‐Miller · 2017 · Frontiers in Cellular Neuroscience
- Centella asiatica (Gotu kola) ethanol extract up-regulates hippocampal brain-derived neurotrophic factor (BDNF), tyrosine kinase B (TrkB) and extracellular signal-regulated protein kinase 1/2 (ERK1/2) signaling in chronic electrical stress model in rats.Dwi Cahyani Ratna Sari, Nur Arfian, Untung Tranggono, Wiwit Ananda Wahyu Setyaningsih, Muhammad Mansyur Romi, Noriaki Emoto · 2019 · PubMed Central
- Acute forced exercise increasesBdnf IV mRNAand reduces exploratory behavior in C57BL/6J miceAndrew C. Venezia, Molly M. Hyer, Erica R. Glasper, Stephen M. Roth, Elizabeth M. Quinlan · 2019 · Genes Brain & Behavior
- Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal NeuronsCharlotte Tacke, Peter S. DiStefano, Ronald M. Lindsay, Kristin Metzdorf, Marta Zagrebelsky, Martin Körte · 2022 · Frontiers in Molecular Neuroscience
- Activity-dependent alterations in the sensitivity to BDNF-TrkB signaling may promote excessive dendritic arborization and spinogenesis in fragile X syndrome in order to compensate for compromised postsynaptic activitySang Woo Kim, Kyoungjoo Cho · 2014 · Medical Hypotheses
- Brain-derived neurotrophic factor stimulates growth of pituitary melanotrope cells in an autocrine wayMiyuki Kuribara, Mark W. Hess, Maxime Cazorla, Eric W. Roubos, Wim J.J.M. Scheenen, Bruce G. Jenks · 2010 · General and Comparative Endocrinology
- Repeated Exposure to Sublethal Doses of the Organophosphorus Compound VX Activates BDNF Expression in Mouse BrainJosé M. Pizarro, Wenling E. Chang, Mariama J. Bah, L. K. M. Wright, George Andrew Saviolakis, A. Alagappan, Christopher L. Robison, Janmay Shah, James L. Meyerhoff, Douglas M. Cerasoli et al. · 2012 · Toxicological Sciences
- Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cellsXiaoxi Yuan, Liping Yang, Zhonglin Yang, Wei‐Lie Xiao, Han‐Dong Sun, Gui-Sheng Wu, Huai‐Rong Luo · 2014 · Journal of Ethnopharmacology
- NCAM in Neuropsychiatric and Neurodegenerative DisordersLeann H. Brennaman, Patricia F. Maness · 2008 · Neurochemical Research
- Dendritic Spines and Pain MemoryCurtis A. Benson, Jared F King, Marike L. Reimer, Sierra D. Kauer, Stephen G. Waxman, Andrew M. Tan · 2022 · The Neuroscientist
- Mechanism of N6-Methyladenosine Modification in the Pathogenesis of DepressionZhuohang Xian, Liangjing Tian, Zhixuan Yao, Lei Cao, Zhilin Jia, Gangqin Li · 2024 · Molecular Neurobiology
- Arbutin intervention ameliorates memory impairment in a rat model of lysolecethin induced demyelination: Neuroprotective and anti-inflammatory effectsManouchehr Ashrafpour, Mohammad-Javad Nasr-Taherabadi, Alie Sabouri-Rad, Soheila Hosseinzadeh, Fereshteh Pourabdolhossein · 2024 · Behavioural Brain Research
- Calotropis gigantea Promotes Neuritogenesis and Synaptogenesis through Activation of NGF-TrkA-Erk1/2 Signaling in Rat Hippocampal NeuronsMd. Nazmul Haque, Md. Mohibbullah, Yong‐Ki Hong, Il Soo Moon · 2018 · The American Journal of Chinese Medicine
- Low-Intensity Pulsed Ultrasound Attenuates Postoperative Neurocognitive Impairment and Salvages Hippocampal Synaptogenesis in Aged MiceQian Wang, Taotao Liu, Huixian Chang, Zhengqian Li, Lei Chen, Xinning Mi, Hua-Yi Xing, Xiaoxiao Wang, Jingshu Hong, Kaixi Liu et al. · 2023 · Brain Sciences
- MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable ShockKatrine Svenningsen, Morten Trillingsgaard Venø, Kim Henningsen, Anne Stephanie Mallien, Line Jensen, Trine Tang Christensen, Jørgen Kjems, Barbara Vollmayr, Ove Wiborg · 2016 · PLoS ONE
- Chronic light deprivation induces different effects on spatial and fear memory and hippocampal BDNF/TRKB expression during light and dark phases of rat diurnal rhythmNader Asadian, Houman Parsaie, Abbas Ali Vafaei, Masoomeh Dadkhah, Samira Omoumi, Katayoun Sedaghat · 2021 · Behavioural Brain Research
- A Multi-Target and Multi-Channel Mechanism of Action for Jiawei Yinhuo Tang in the Treatment of Social Communication Disorders in Autism: Network Pharmacology and Molecular Docking StudiesLinlin Zhang, Ciai Lai, Su Yanhong, Gan Huizhong, Yongchun Li, Yang Zhen, Xu Shan, Fengying Gong, Ying Lv, Jingjun Li et al. · 2022 · Evidence-based Complementary and Alternative Medicine
- Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse modelKyle A. Brown, Jessica M. Carpenter, Collin J. Preston, Helaina Danielle Ludwig, Kendall B. Clay, Donald A. Harn, Thomas Norberg, John J. Wagner, Nikolay M. Filipov · 2021 · Life Sciences
- Dual 5-HT6/SERT ligands for mitigating neuropsychiatric symptoms of dementia exerting neuroprotection against amyloid-β toxicity, memory preservation, and antidepressant-like propertiesAgata Siwek, Monika Marcinkowska, Monika Głuch‐Lutwin, Barbara Mordyl, Małgorzata Wolak, Magdalena Jastrzębska‐Więsek, Natalia Wilczyńska-Zawal, Elżbieta Wyska, Katarzyna Szafrańska, Tadeusz P. Karcz et al. · 2024 · European Journal of Medicinal Chemistry