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THE STRUCTURE OF DNA
Abstract
It would be superfluous at a Symposium on Vi-ruses to introduce a paper on the structure of DNA with a discussion on its importance to the problem of virus reproduction. Instead we shall not only assume that DNA is important, but in addition that it is the carrier of the genetic specificity of the virus (for argument, see Hershey, this volume) and thus must possess in some sense the capacity for exact self-duplication. In this paper we shall de-scribe a structure for DNA which suggests a mech-anism for its self-duplication and allows us to pro-pose, for the first time, a detailed hypothesis on the atomic level for the self-reproduction f genetic material. We first discuss the chemical and physical-chemi-
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Cited by
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Goodwin, S., McPherson, J. D., & McCombie, W. R. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.49 · Cited by 4,352
(1958) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 880
Origins, structures, and functions of circulating DNA in oncology
Thierry, A. R., El Messaoudi, S., Gahan, P. B., Anker, P., & Stroun, M. (2016) · Cancer and Metastasis Reviews · doi:10.1007/s10555-016-9629-x · Cited by 818
Lee, H., Popodi, E., Tang, H., & Foster, P. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210309109 · Cited by 681
Biochemical Basis of DNA Replication Fidelity
Goodman, M. F., Creighton, S., Bloom, L. B., Petruska, J., & Kunkel, T. A. (1993) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239309086792 · Cited by 446
Metadata
- Authors
- Watson, J. D., & Crick, F. H. C.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1953-01-01
- Volume
- 18
- Issue
- 0
- Pages
- 123-131
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W2127674396
- Cited by
- 1,120
- References
- 0
- Type
- posted content
- Language
- en
- Open access
- closed
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- Watson, J. D., & Crick, F. H. C. (1953). THE STRUCTURE OF DNA. Cold Spring Harbor Symposia on Quantitative Biology. https://doi.org/10.1101/sqb.1953.018.01.020
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