The DOI matches its Crossref record.
Unzipping Kinetics of Double-Stranded DNA in a Nanopore
Open accessAbstract
We studied the unzipping of single molecules of double-stranded DNA by pulling one of their two strands through a narrow protein pore. Polymerase chain reaction analysis yielded the first direct proof of DNA unzipping in such a system. The time to unzip each molecule was inferred from the ionic current signature of DNA traversal. The distribution of times to unzip under various experimental conditions fit a simple kinetic model. Using this model, we estimated the enthalpy barriers to unzipping and the effective charge of a nucleotide in the pore, which was considerably smaller than previously assumed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore
Stoddart, D., Heron, A. J., Mikhailova, E., Maglia, G., & Bayley, H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901054106 · Cited by 482
(2007) · Cited by 33
Metadata
- Authors
- Sauer-Budge, A. F., Nyamwanda, J. A., Lubensky, D. K., & Branton, D.
- Venue
- Physical Review Letters
- Publisher
- American Physical Society (APS)
- Published
- 2003-06-09
- Volume
- 90
- Issue
- 23
- Pages
- 238101-238101
- ISSN
- 0031-9007 (ISSN-L)
- 1079-7114
- OpenAlex
- W2073975746
- Cited by
- 312
- References
- 0
- FWCI
- 12.55
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Unzipping Kinetics of Double-Stranded DNA in a Nanopore. https://app.cochat.ai/papers/10.1103/physrevlett.90.238101
- The paper
- Sauer-Budge, A. F., Nyamwanda, J. A., Lubensky, D. K., & Branton, D. (2003). Unzipping Kinetics of Double-Stranded DNA in a Nanopore. Physical Review Letters. https://doi.org/10.1103/physrevlett.90.238101
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
