The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Mitochondrial GFA2 Is Required for Synergid Cell Death in Arabidopsis
Open accessAbstract
Little is known about the molecular processes that govern female gametophyte (FG) development and function, and few FG-expressed genes have been identified. We report the identification and phenotypic analysis of 31 new FG mutants in Arabidopsis. These mutants have defects throughout development, indicating that FG-expressed genes govern essentially every step of FG development. To identify genes involved in cell death during FG development, we analyzed this mutant collection for lines with cell death defects. From this analysis, we identified one mutant, gfa2, with a defect in synergid cell death. Additionally, the gfa2 mutant has a defect in fusion of the polar nuclei. We isolated the GFA2 gene and show that it encodes a J-domain-containing protein. Of the J-domain-containing proteins in Saccharomyces cerevisiae (budding yeast), GFA2 is most similar to Mdj1p, which functions as a chaperone in the mitochondrial matrix. GFA2 is targeted to mitochondria in Arabidopsis and partially complements a yeast mdj1 mutant, suggesting that GFA2 is the Arabidopsis ortholog of yeast Mdj1p. These data suggest a role for mitochondria in cell death in plants.
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Cites
Mitochondrial endonuclease G is important for apoptosis in C. elegans
Parrish, J., Li, L., Klotz, K., Ledwich, D., Wang, X., & Xue, D. (2001) · Nature · doi:10.1038/35083608 · Cited by 427
Cited by
Pagnussat, G. C., Yu, H.-J., Ngo, Q. A., Rajani, S., Mayalagu, S., Johnson, C. S., Capron, A., Xie, L.-F., Ye, D., & Sundaresan, V. (2005) · Development · doi:10.1242/dev.01595 · Cited by 591
Female Gametophyte Development
Yadegari, R. (2004) · THE PLANT CELL ONLINE · doi:10.1105/tpc.018192 · Cited by 451
Ueda, M., Zhang, Z., & Laux, T. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.01.009 · Cited by 301
Heat stress induces ferroptosis-like cell death in plants
Distéfano, A. M., Martin, M. V., Córdoba, J. P., Bellido, A. M., D’Ippólito, S., Colman, S. L., Soto, D., Roldán, J. A., Bartoli, C. G., Zabaleta, E. J., et al. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201605110 · Cited by 268
Zheng, Z., Xia, Q., Dauk, M., Shen, W., Selvaraj, G., & Zou, J. (2003) · The Plant Cell · doi:10.1105/tpc.012427 · Cited by 261
Metadata
- Authors
- Christensen, C. A., Gorsich, S. W., Brown, R. H., Jones, L. G., Brown, J., Shaw, J. M., & Drews, G. N.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-09
- Volume
- 14
- Issue
- 9
- Pages
- 2215-2232
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2116303974
- Cited by
- 175
- References
- 1
- FWCI
- 3.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Christensen, C. A., Gorsich, S. W., Brown, R. H., Jones, L. G., Brown, J., Shaw, J. M., & Drews, G. N. (2002). Mitochondrial GFA2 Is Required for Synergid Cell Death in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.002170
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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