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Cell Pattern in the Arabidopsis Root Epidermis Determined by Lateral Inhibition with Feedback
Open accessAbstract
In the root epidermis of Arabidopsis, hair and nonhair cell types are specified in a distinct position-dependent pattern. Here, we show that transcriptional feedback loops between the WEREWOLF (WER), CAPRICE (CPC), and GLABRA2 (GL2) genes help to establish this pattern. Positional cues bias the expression of the WER MYB gene, leading to the induction of CPC and GL2 in cells located in a particular position (N) and adoption of the nonhair fate. The truncated MYB encoded by CPC mediates a lateral inhibition mechanism to negatively regulate WER, GL2, and its own gene in the alternative position (H) to induce the hair fate. These results provide a molecular genetic framework for understanding the determination of a cell-type pattern in plants.
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Cited by
Yanhui, C., Xiaoyuan, Y., Kun, H., Meihua, L., Jigang, L., Zhaofeng, G., Zhiqiang, L., Yunfei, Z., Xiaoxiao, W., Xiaoming, Q., et al. (2006) · Plant Molecular Biology · doi:10.1007/s11103-005-2910-y · Cited by 992
Quattrocchio, F., Verweij, W., Kroon, A., Spelt, C., Mol, J., & Koes, R. (2006) · The Plant Cell · doi:10.1105/tpc.105.034041 · Cited by 401
Shahan, R., Hsu, C.-W., Nolan, T. M., Cole, B. J., Taylor, I. W., Greenstreet, L., Zhang, S., Afanassiev, A., Vlot, A. H. C., Schiebinger, G., et al. (2022) · Developmental Cell · doi:10.1016/j.devcel.2022.01.008 · Cited by 363
Arabidopsis MYB68 in development and responses to environmental cues
Feng, C., Andreasson, E., Maslak, A., Mock, H. P., Mattsson, O., & Mundy, J. (2004) · Plant Science · doi:10.1016/j.plantsci.2004.06.014 · Cited by 115
Root Hairs: An under-explored target for sustainable cereal crop production
Tsang, I., Atkinson, J. A., Rawsthorne, S., Cockram, J., & Leigh, F. (2023) · doi:10.31219/osf.io/fh2u5 · Cited by 17
Metadata
- Authors
- Lee, M. M., & Schiefelbein, J.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-03
- Volume
- 14
- Issue
- 3
- Pages
- 611-618
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2134468334
- Cited by
- 219
- References
- 0
- FWCI
- 18.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Lee, M. M., & Schiefelbein, J. (2002). Cell Pattern in the Arabidopsis Root Epidermis Determined by Lateral Inhibition with Feedback. The Plant Cell. https://doi.org/10.1105/tpc.010434
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