The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Stomatal Development and Patterning Are Regulated by Environmentally Responsive Mitogen-Activated Protein Kinases in Arabidopsis
Open accessAbstract
Stomata are specialized epidermal structures that regulate gas (CO2 and O2) and water vapor exchange between plants and their environment. In Arabidopsis thaliana, stomatal development is preceded by asymmetric cell divisions, and stomatal distribution follows the one-cell spacing rule, reflecting the coordination of cell fate specification. Stomatal development and patterning are regulated by both genetic and environmental signals. Here, we report that Arabidopsis MITOGEN-ACTIVATED PROTEIN KINASE3 (MPK3) and MPK6, two environmentally responsive mitogen-activated protein kinases (MAPKs), and their upstream MAPK kinases, MKK4 and MKK5, are key regulators of stomatal development and patterning. Loss of function of MKK4/MKK5 or MPK3/MPK6 disrupts the coordinated cell fate specification of stomata versus pavement cells, resulting in the formation of clustered stomata. Conversely, activation of MKK4/MKK5-MPK3/MPK6 causes the suppression of asymmetric cell divisions and stomatal cell fate specification, resulting in a lack of stomatal differentiation. We further establish that the MKK4/MKK5-MPK3/MPK6 module is downstream of YODA, a MAPKKK. The establishment of a complete MAPK signaling cascade as a key regulator of stomatal development and patterning advances our understanding of the regulatory mechanisms of intercellular signaling events that coordinate cell fate specification during stomatal development.
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Cites
Di Laurenzio, L., Wysocka-Diller, J., Malamy, J. E., Pysh, L., Helariutta, Y., Freshour, G., Hahn, M. G., Feldmann, K. A., & Benfey, P. N. (1996) · Cell · doi:10.1016/s0092-8674(00)80115-4 · Cited by 1,124
Emerging MAP kinase pathways in plant stress signalling
Nakagami, H., Pitzschke, A., & Hirt, H. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2005.05.009 · Cited by 676
Cited by
MAPK cascade signalling networks in plant defence
Pitzschke, A., Schikora, A., & Hirt, H. (2009) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2009.06.008 · Cited by 710
Saibo, N. J. M., Lourenço, T., & Oliveira, M. M. (2009) · Annals of Botany · doi:10.1093/aob/mcn227 · Cited by 483
The Signaling Peptide EPF2 Controls Asymmetric Cell Divisions during Stomatal Development
Hunt, L., & Gray, J. E. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.069 · Cited by 435
Mechanisms of Stomatal Development
Pillitteri, L. J., & Torii, K. U. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105451 · Cited by 389
Ning, J., Li, X., Hicks, L. M., & Xiong, L. (2010) · Plant Physiology · doi:10.1104/pp.109.149856 · Cited by 386
Metadata
- Authors
- Wang, H., Ngwenyama, N., Liu, Y., Walker, J. C., & Zhang, S.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-01-01
- Volume
- 19
- Issue
- 1
- Pages
- 63-73
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2152223980
- Cited by
- 778
- References
- 2
- FWCI
- 53.52
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, H., Ngwenyama, N., Liu, Y., Walker, J. C., & Zhang, S. (2007). Stomatal Development and Patterning Are Regulated by Environmentally Responsive Mitogen-Activated Protein Kinases in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.106.048298
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