The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
The Arabidopsis Mediator Subunit MED25 Differentially Regulates Jasmonate and Abscisic Acid Signaling through Interacting with the MYC2 and ABI5 Transcription Factors
Open accessAbstract
Transcriptional regulation plays a central role in plant hormone signaling. At the core of transcriptional regulation is the Mediator, an evolutionarily conserved, multisubunit complex that serves as a bridge between gene-specific transcription factors and the RNA polymerase machinery to regulate transcription. Here, we report the action mechanisms of the MEDIATOR25 (MED25) subunit of the Arabidopsis thaliana Mediator in regulating jasmonate- and abscisic acid (ABA)-triggered gene transcription. We show that during jasmonate signaling, MED25 physically associates with the basic helix-loop-helix transcription factor MYC2 in promoter regions of MYC2 target genes and exerts a positive effect on MYC2-regulated gene transcription. We also show that MED25 physically associates with the basic Leu zipper transcription factor ABA-INSENSITIVE5 (ABI5) in promoter regions of ABI5 target genes and shows a negative effect on ABI5-regulated gene transcription. Our results reveal that underlying the distinct effects of MED25 on jasmonate and ABA signaling, the interaction mechanisms of MED25 with MYC2 and ABI5 are different. These results highlight that the MED25 subunit of the Arabidopsis Mediator regulates a wide range of signaling pathways through selectively interacting with specific transcription factors.
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Cites
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JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
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The JAZ family of repressors is the missing link in jasmonate signalling
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Plant Immunity to Insect Herbivores
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COI1 : An Arabidopsis Gene Required for Jasmonate-Regulated Defense and Fertility
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Cited by
Wasternack, C., & Hause, B. (2013) · Annals of Botany · doi:10.1093/aob/mct067 · Cited by 2,629
Kazan, K., & Manners, J. M. (2013) · Molecular Plant · doi:10.1093/mp/sss128 · Cited by 1,081
Diverse roles of jasmonates and ethylene in abiotic stress tolerance
Kazan, K. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2015.02.001 · Cited by 854
Modularity in Jasmonate Signaling for Multistress Resilience
Howe, G. A., Major, I. T., & Koo, A. J. (2018) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042817-040047 · Cited by 697
Cheng, M.-C., Liao, P.-M., Kuo, W.-W., & Lin, T.-P. (2013) · PLANT PHYSIOLOGY · doi:10.1104/pp.113.221911 · Cited by 657
Metadata
- Authors
- Chen, R., Jiang, H., Li, L., Zhai, Q., Qi, L., Zhou, W., Liu, X., Li, H., Zheng, W., Sun, J., & Li, C.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-07
- Volume
- 24
- Issue
- 7
- Pages
- 2898-2916
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2156558407
- Cited by
- 408
- References
- 95
- FWCI
- 24.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: The Arabidopsis Mediator Subunit MED25 Differentially Regulates Jasmonate and Abscisic Acid Signaling through Interacting with the MYC2 and ABI5 Transcription Factors. https://app.cochat.ai/papers/10.1105/tpc.112.098277
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- Chen, R., Jiang, H., Li, L., Zhai, Q., Qi, L., Zhou, W., Liu, X., Li, H., Zheng, W., Sun, J., & Li, C. (2012). The Arabidopsis Mediator Subunit MED25 Differentially Regulates Jasmonate and Abscisic Acid Signaling through Interacting with the MYC2 and ABI5 Transcription Factors. The Plant Cell. https://doi.org/10.1105/tpc.112.098277
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