The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
A Distal CCAAT /NUCLEAR FACTOR Y Complex Promotes Chromatin Looping at the FLOWERING LOCUS T Promoter and Regulates the Timing of Flowering in Arabidopsis
Open accessAbstract
For many plant species, reproductive success relies on the proper timing of flowering, and photoperiod provides a key environmental input. Photoperiod-dependent flowering depends on timely expression of FLOWERING LOCUS T (FT); however, the coordination of various cis-regulatory elements in the FT promoter is not well understood. Here, we provide evidence that long-distance chromatin loops bring distal enhancer elements into close association with the proximal promoter elements bound by CONSTANS (CO). Additionally, we show that NUCLEAR FACTOR Y (NF-Y) binds a CCAAT box in the distal enhancer element and that CCAAT disruption dramatically reduces FT promoter activity. Thus, we propose the recruitment model of photoperiod-dependent flowering where NF-Y complexes, bound at the FT distal enhancer element, help recruit CO to proximal cis-regulatory elements and initiate the transition to reproductive growth.
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Cites
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Purification and Characterization
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FT Protein Movement Contributes to Long-Distance Signaling in Floral Induction of Arabidopsis
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Distinct Roles of CONSTANS Target Genes in Reproductive Development of Arabidopsis
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Cited by
New insights into gibberellin signaling in regulating flowering in Arabidopsis
Bao, S., Hua, C., Shen, L., & Yu, H. (2020) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12892 · Cited by 386
Circadian Clock and Photoperiodic Flowering in Arabidopsis: CONSTANS Is a Hub for Signal Integration
Shim, J. S., Kubota, A., & Imaizumi, T. (2017) · Plant Physiology · doi:10.1104/pp.16.01327 · Cited by 359
Metadata
- Authors
- Cao, S., Kumimoto, R. W., Gnesutta, N., Calogero, A. M., Mantovani, R., & Holt, B. F.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-03
- Volume
- 26
- Issue
- 3
- Pages
- 1009-1017
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2162917822
- Cited by
- 294
- References
- 53
- FWCI
- 25.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: A Distal CCAAT /NUCLEAR FACTOR Y Complex Promotes Chromatin Looping at the FLOWERING LOCUS T Promoter and Regulates the Timing of Flowering in Arabidopsis. https://app.cochat.ai/papers/10.1105/tpc.113.120352
- The paper
- Cao, S., Kumimoto, R. W., Gnesutta, N., Calogero, A. M., Mantovani, R., & Holt, B. F. (2014). A Distal CCAAT /NUCLEAR FACTOR Y Complex Promotes Chromatin Looping at the FLOWERING LOCUS T Promoter and Regulates the Timing of Flowering in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.113.120352
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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