The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The ROOT MERISTEMLESS1/CADMIUM SENSITIVE2 Gene Defines a Glutathione-Dependent Pathway Involved in Initiation and Maintenance of Cell Division during Postembryonic Root Development
Open accessAbstract
Activation of cell division in the root apical meristem after germination is essential for postembryonic root development. Arabidopsis plants homozygous for a mutation in the ROOT MERISTEMLESS1 (RML1) gene are unable to establish an active postembryonic meristem in the root apex. This mutation abolishes cell division in the root but not in the shoot. We report the molecular cloning of the RML1 gene, which encodes the first enzyme of glutathione (GSH) biosynthesis, gamma-glutamylcysteine synthetase, and which is allelic to CADMIUM SENSITIVE2. The phenotype of the rml1 mutant, which was also evident in the roots of wild-type Arabidopsis and tobacco treated with an inhibitor of GSH biosynthesis, could be relieved by applying GSH to rml1 seedlings. By using a synchronized tobacco cell suspension culture, we showed that the G(1)-to-S phase transition requires an adequate level of GSH. These observations suggest the existence of a GSH-dependent developmental pathway essential for initiation and maintenance of cell division during postembryonic root development.
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Cites
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Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro
Abate, C., Patel, L., Rauscher, F. J., & Curran, T. (1990) · Science · doi:10.1126/science.2118682 · Cited by 1,573
Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.
Toledano, M. B., & Leonard, W. J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.10.4328 · Cited by 657
Cited by
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Cobbett, C., & Goldsbrough, P. (2002) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.53.100301.135154 · Cited by 2,518
Self-citationTsukagoshi, H., Busch, W., & Benfey, P. N. (2010) · Cell · doi:10.1016/j.cell.2010.10.020 · Cited by 1,081
Intrinsic and environmental response pathways that regulate root system architecture
MALAMY, J. E. (2005) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2005.01306.x · Cited by 1,018
Catalase function in plants: a focus on Arabidopsis mutants as stress-mimic models
Mhamdi, A., Queval, G., Chaouch, S., Vanderauwera, S., Van Breusegem, F., & Noctor, G. (2010) · Journal of Experimental Botany · doi:10.1093/jxb/erq282 · Cited by 989
Lillig, C. H., Berndt, C., & Holmgren, A. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2008.06.003 · Cited by 561
Metadata
- Authors
- Vernoux, T., Wilson, R. C., Seeley, K. A., Reichheld, J.-P., Muroy, S., Brown, S., Maughan, S. C., Cobbett, C. S., Van Montagu, M., Inzé, D., May, M. J., & Sung, Z. R.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-01
- Volume
- 12
- Issue
- 1
- Pages
- 97-109
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2102338029
- Cited by
- 576
- References
- 3
- FWCI
- 29.42
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: The ROOT MERISTEMLESS1/CADMIUM SENSITIVE2 Gene Defines a Glutathione-Dependent Pathway Involved in Initiation and Maintenance of Cell Division during Postembryonic Root Development. https://app.cochat.ai/papers/10.1105/tpc.12.1.97
- The paper
- Vernoux, T., Wilson, R. C., Seeley, K. A., Reichheld, J.-P., Muroy, S., Brown, S., Maughan, S. C., Cobbett, C. S., Van Montagu, M., Inzé, D., May, M. J., & Sung, Z. R. (2000). The ROOT MERISTEMLESS1/CADMIUM SENSITIVE2 Gene Defines a Glutathione-Dependent Pathway Involved in Initiation and Maintenance of Cell Division during Postembryonic Root Development. The Plant Cell. https://doi.org/10.1105/tpc.12.1.97
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
