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Minimum redundancy feature selection from microarray gene expression data

Ding, C., Peng, H.·2004·Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003

Abstract

Selecting a small subset of genes out of the thousands of genes in microarray data is important for accurate classification of phenotypes. Widely used methods typically rank genes according to their differential expressions among phenotypes and pick the top-ranked genes. We observe that feature sets so obtained have certain redundancy and study methods to minimize it. Feature sets obtained through the minimum redundancy - maximum relevance framework represent broader spectrum of characteristics of phenotypes than those obtained through standard ranking methods; they are more robust, generalize well to unseen data, and lead to significantly improved classifications in extensive experiments on 5 gene expressions data sets.

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Crossref · 10.1109/csb.2003.1227396

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Metadata

Authors
Ding, C., & Peng, H.
Venue
Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003
Published
2004-03-30
Pages
523-528
OpenAlex
W2153678774
Cited by
506
References
1
FWCI
31.10
Type
conference paper
Language
en
Open access
closed

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