The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Unsupervised Deep Learning Applied to Breast Density Segmentation and Mammographic Risk Scoring
Abstract
Mammographic risk scoring has commonly been automated by extracting a set of handcrafted features from mammograms, and relating the responses directly or indirectly to breast cancer risk. We present a method that learns a feature hierarchy from unlabeled data. When the learned features are used as the input to a simple classifier, two different tasks can be addressed: i) breast density segmentation, and ii) scoring of mammographic texture. The proposed model learns features at multiple scales. To control the models capacity a novel sparsity regularizer is introduced that incorporates both lifetime and population sparsity. We evaluated our method on three different clinical datasets. Our state-of-the-art results show that the learned breast density scores have a very strong positive relationship with manual ones, and that the learned texture scores are predictive of breast cancer. The model is easy to apply and generalizes to many other segmentation and scoring problems.
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Cited by
A survey on deep learning in medical image analysis
Litjens, G., Kooi, T., Bejnordi, B. E., Setio, A. A. A., Ciompi, F., Ghafoorian, M., van der Laak, J. A. W. M., van Ginneken, B., & Sánchez, C. I. (2017) · Medical Image Analysis · doi:10.1016/j.media.2017.07.005 · Cited by 15,332
Artificial intelligence in radiology
Hosny, A., Parmar, C., Quackenbush, J., Schwartz, L. H., & Aerts, H. J. W. L. (2018) · Nature Reviews Cancer · doi:10.1038/s41568-018-0016-5 · Cited by 3,803
Acharya, U. R., Oh, S. L., Hagiwara, Y., Tan, J. H., & Adeli, H. (2018) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2017.09.017 · Cited by 1,647
Acharya, U. R., Fujita, H., Oh, S. L., Hagiwara, Y., Tan, J. H., & Adam, M. (2017) · Information Sciences · doi:10.1016/j.ins.2017.06.027 · Cited by 937
Convolutional neural networks in medical image understanding: a survey
Sarvamangala, D. R., & Kulkarni, R. V. (2022) · Evolutionary Intelligence · doi:10.1007/s12065-020-00540-3 · Cited by 917
Metadata
- Authors
- Kallenberg, M., Petersen, K., Nielsen, M., Ng, A. Y., Diao, P., Igel, C., Vachon, C. M., Holland, K., Winkel, R. R., Karssemeijer, N., & Lillholm, M.
- Venue
- IEEE Transactions on Medical Imaging
- Published
- 2016-05
- Volume
- 35
- Issue
- 5
- Pages
- 1322-1331
- ISSN
- 0278-0062 (ISSN-L)
- 1558-254X
- OpenAlex
- W2338271170
- Cited by
- 439
- References
- 4
- FWCI
- 49.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kallenberg, M., Petersen, K., Nielsen, M., Ng, A. Y., Diao, P., Igel, C., Vachon, C. M., Holland, K., Winkel, R. R., Karssemeijer, N., & Lillholm, M. (2016). Unsupervised Deep Learning Applied to Breast Density Segmentation and Mammographic Risk Scoring. IEEE Transactions on Medical Imaging. https://doi.org/10.1109/tmi.2016.2532122
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