(−)‐Epigallocatechin‐3‐gallate and EZH 2 inhibitor GSK 343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells

Ying, Le; Yan, Feng; Williams, Bryan RG; Xu, Ping; Li, Xin; Zhao, Yueling; Hu, Yiqun; Wang, Yuefei; Xu, Dakang; Dai, Jing

doi:10.1111/1440-1681.12854

(−)‐Epigallocatechin‐3‐gallate and EZH 2 inhibitor GSK 343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells

Summary Epigallocatechin‐3‐gallate ( EGCG ) is a type of catechin. It exhibits excellent antioxidant effects and anti‐tumour activities for cancer chemoprevention. The mechanism of anti‐tumour effects of EGCG on different cancers has been studied for the past few decades, but remains controversia…