The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ion release from calcium and fluoride containing dental varnishes
Abstract
Background: A range of dental varnishes have been commercialized recently that contain calcium and inorganic phosphate in addition to fluoride. The aim of this study was to analyse the fluoride, calcium and inorganic phosphate ion release from: (1) MI Varnish containing casein phosphopeptide‐amorphous calcium phosphate (CPP‐ACP); (2) Clinpro White containing functionalized tricalcium phosphate (fTCP); (3) Enamel Pro containing amorphous calcium phosphate; (4) Bifluorid 5 containing calcium fluoride; and (5) Duraphat (no added calcium control). Methods: The varnishes were applied to a standardized surface area of polyvinyl chloride (n = 7 per group) and immersed in 25 g of distilled deionized water which was changed at 1, 4, 24, 72 and 168 hours. The ion release was determined by ion chromatography and expressed as μmol (cumulative) per gram of varnish. Results: All varnishes released measurable fluoride and calcium, however only MI Varnish and Enamel Pro released significant levels of inorganic phosphate. At 24 hours the order of cumulative fluoride release was: 1>3>4>2=5 with 1 significantly higher (p < 0.05) than the rest. At 72 and 168 hours, the cumulative calcium release was: 1>4>3>2=5 with 1 significantly higher (p < 0.05) than the rest. Conclusions: MI Varnish containing CPP‐ACP had the highest release of calcium and fluoride ions.
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“In vitro data suggest that additives in fluoride varnishes can potentially enhance or diminish fluoride ion release, influencing the anticariogenicity of the product.15,16”
In the citing paper
“Cochrane et al.15 noted that MI Varnish's rapid ion release is due to the CPP–ACP complex's high-water solubility, compensating for brief oral cavity duration.”
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Citations
Cites
Fluoride varnishes for preventing dental caries in children and adolescents
Marinho, V. C., Worthington, H. V., Walsh, T., & Clarkson, J. E. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002279.pub2 · Cited by 1,022
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Cited by
Sorted by citations
Baidya, D., Pathivada, L., Garg, N., Karthik, K. M., Jain, A. K., & Bhyri, P. (2026) · International Journal of Clinical Pediatric Dentistry · doi:10.5005/jp-journals-10005-3470
Metadata
- Authors
- Cochrane, N., Shen, P., Yuan, Y., & Reynolds, E.
- Venue
- Australian Dental Journal
- Publisher
- Wiley
- Published
- 2014-02-04
- Volume
- 59
- Issue
- 1
- Pages
- 100-105
- ISSN
- 0045-0421
- 1834-7819
- Cited by
- 90
- References
- 1
- Language
- en
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