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On minor histocompatibility antigens, mixed chimerism, and transplantation tolerance
Open accessAbstract
The article from Mahr et al. on page 968 clarifies the contributions of major and minor histocompatibility antigens to the induction of mixed chimerism and allograft tolerance when using a clinically relevant noncytoreductive regimen.
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Any heterogeneous antigen that can be processed and expressed through MHC molecules is a potential immunogen.
“Any heterogeneous antigen that could be processed and expressed through MHC molecules is a potential immunogen [4].”
From Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine (2023) · cites this paper as [4]
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Cites
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Research works printed but not linked: 5
- Kawai, 2008, HLA-mismatched renal transplantation without maintenance immunosuppression, N Engl J Med., 358, 353, 10.1056/NEJMoa071074 · DOI
- Domenig, 2005, Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol, J Immunol., 175, 51, 10.4049/jimmunol.175.1.51 · DOI
- Luo, 2007, Non-myeloablative mixed chimerism approaches and tolerance, a split decision, Eur J Immunol., 37, 1233, 10.1002/eji.200636938 · DOI
- Mahr B, Pilat N, Granofszky N, et al. Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions [published online ahead of print July 6, 2020]. Am J Transplant. https://doi.org/10.1111/ajt.16177. · DOI
- Pilat, 2016, Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization, JCI Insight., 1, 10.1172/jci.insight.85911 · DOI
Cited by
Sorted by citations
Kasravi, M., Ahmadi, A., Babajani, A., Mazloomnejad, R., Hatamnejad, M. R., Shariatzadeh, S., Bahrami, S., & Niknejad, H. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00348-z · Cited by 316
“Any heterogeneous antigen that could be processed and expressed through MHC molecules is a potential immunogen [4].”
Background
Metadata
- Authors
- Sánchez-Fueyo, A., & Dazzi, F.
- Affiliations
- King's College London (GB)
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2021-03
- Volume
- 21
- Issue
- 3
- Pages
- 919-920
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W3066291154
- Cited by
- 3
- References
- 0
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- American Journal of Transplantation (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Medical Research Council (MR/P007694/1)
- Topics
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- minor histocompatibility antigens, mixed chimerism, allograft tolerance, major histocompatibility complex, transplantation immunology
- MeSH terms
- Immune Tolerance, Minor Histocompatibility Antigens, Transplantation Chimera, Transplantation Tolerance, Chimerism
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