Cited by 8Aortic Disease and Treatment ApproachesTrauma and Emergency Care StudiesConnective tissue disorders research

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Time critical diagnoses and transfers of patients with acute type A aortic dissection in the UK : national audit of current practice*

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Abstract

Summary: Background: Type A aortic dissection repair is one of the most common emergency cardiac surgical procedures undertaken in the UK and has a high mortality. Early diagnosis and prompt surgery by an expert cardiac surgical team is crucial. Little is known about the patient's journey from first symptoms until surgery. Methods: The Association for Cardiothoracic Anaesthesia and Critical Care undertook a prospective national audit of the management of type A aortic dissection in the UK. Results: The details of 334 patients with type A aortic dissection were reported by 28 UK cardiac centres over 12 months. Median (IQR [range]) time from onset of symptoms until arrival in an emergency department was 2.3 (1.4–4.7 [0.1–491.6]) h. Median (IQR [range]) time between arrival in the emergency department and the start of surgery was 9.5 (6.1–18.2 [0.8–363.5]) h. Delays in diagnosis and transfers were reported in 158 (47.3%) patients. Fifty‐two patients (15.6%) had an initial misdiagnosis. The condition of 56 patients (16.8%) deteriorated clinically before arrival in the operating theatre. A medical doctor accompanied 50 patients (15.0%) during transfer. Sixty‐four patients (19.2%) died in hospital with 41 (12.3%) dying within the first 5 days after surgery. Conclusions: This audit provides a snapshot of current practice for patients with type A aortic dissection in the UK. Our findings show the acuity, clinical severity and vulnerability of patients with type A aortic dissection, and the deficits in the process of diagnosis and the quality of transfer. This audit demonstrates the need for the implementation of comprehensive, regionally governed, interdisciplinary medical management for every patient with type A aortic dissection.

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Figure 1 Study flow diagram of patients reported, included and analysed.
Figure 1 Study flow diagram of patients reported, included and analysed.CC BY · PubMed Central
Figure 2 Postoperative mortality of patients with acute type A aortic dissection by postoperative day.
Figure 2 Postoperative mortality of patients with acute type A aortic dissection by postoperative day.CC BY · PubMed Central

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References 11 · Cited by 8

Research works printed but not linked: 11

  1. 10.5837/bjc.2023.009 · DOI
  2. 10.1177/17511437231162219 · DOI
  3. 10.1136/bmj.m304 · DOI
  4. 10.1093/eurheartj/ehab586 · DOI
  5. 10.1016/j.jtcvs.2022.09.034 · DOI
  6. 10.1111/anae.15070 · DOI
  7. 10.1111/anae.14734 · DOI
  8. 10.1097/HJH.0000000000002453 · DOI · Paper page
  9. 10.1016/S0140‐6736(22)01970‐5 · DOI
  10. 10.1136/emermed‐2023‐213362 · DOI
  11. 10.2147/AMEP.S259908 · DOI

Metadata

Authors
Gilbey, T., Milne, B., Agarwal, S., Choi, S., Kendall, S., Arrowsmith, J. E., Kunst, G., & the ACTACC Linkperson Network
Affiliations
  • King's College Hospital NHS Foundation Trust (GB)
  • University of Manchester (GB)
  • University of Hong Kong (HK)
  • NHS England (GB)
  • Papworth Hospital NHS Foundation Trust (GB)
  • King's College London (GB)
Corresponding author
Milne, Benjamin
Venue
Anaesthesia
Publisher
Wiley
Published
2024-10-07
Volume
80
Issue
3
Pages
248-258
ISSN
  • 0003-2409 (ISSN-L)
  • 1365-2044
OpenAlex
W4403199295
Cited by
8
References
11
Citations by year
2026: 3 · 2025: 4 · 2024: 1
FWCI
2.32
Type
journal article
Language
en
Open access
Locations
  • Anaesthesia (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
  • Health Sciences › Medicine › Emergency Medicine › Trauma and Emergency Care Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
Keywords
type A aortic dissection, emergency aortic repair, time to diagnosis, patient transfer, delayed diagnosis, misdiagnosis, in-hospital mortality, emergency department delays, quality of care, multidisciplinary management

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CoChat. (2026). Citation check: Time critical diagnoses and transfers of patients with acute type A aortic dissection in the UK : national audit of current practice*. https://app.cochat.ai/papers/10.1111/anae.16443
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Gilbey, T., Milne, B., Agarwal, S., Choi, S., Kendall, S., Arrowsmith, J. E., Kunst, G., & the ACTACC Linkperson Network. (2025). Time critical diagnoses and transfers of patients with acute type A aortic dissection in the UK : national audit of current practice*. Anaesthesia. https://doi.org/10.1111/anae.16443