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Epidermal necrolysis: characterization of different phenotypes using an unsupervised clustering analysis
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Factor analysis and hierarchical clustering on baseline clinical and biological data for 113 patients with epidermal necrolysis found 3 clusters: 1 cluster of sicker patients with high mortality and 2 clusters of younger patients.
“Bettuzzi et al (2022) utilized factor analysis and hierarchical clustering on baseline clinical and biological data for 113 patients with epidermal necrolysis, finding 3 clusters: 1 cluster of sicker patients with high mortality and 2 clusters of younger patients.”
From Artificial intelligence–enabled precision medicine for inflammatory skin diseases (2026) · cites this paper as Bettuzzi et al, 2022
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Artificial intelligence–enabled precision medicine for inflammatory skin diseases
Tang, A. S., Wei, M. L., Haemel, A., La, C., Sirota, M., & Lee, E. Y. (2026) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.10.596 · Cited by 10
Metadata
- Authors
- Bettuzzi, T., Hua, C., Diaz, E., Colin, A., Wolkenstein, P., de Prost, N., & Ingen‐Housz‐Oro, S.
- Affiliations
- Université Paris-Est Créteil (FR)
- Service de Dermatologie
- Assistance Publique – Hôpitaux de Paris (FR)
- Corresponding author
- Bettuzzi, Thomas
- ORCID
- Venue
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2022-04-06
- Volume
- 186
- Issue
- 6
- Pages
- 1037-1039
- ISSN
- 0007-0963 (ISSN-L)
- 1365-2133
- OpenAlex
- W4206793633
- Cited by
- 7
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2023: 1 · 2022: 1
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- British Journal of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
- Health Sciences › Medicine › Dermatology › Genetic and rare skin diseases.
- Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
- Keywords
- epidermal necrolysis, phenotypes, unsupervised clustering, disease heterogeneity, epidermolysis bullosa
- MeSH terms
- Humans, Phenotype, Stevens-Johnson Syndrome, Cluster Analysis
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