In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML 29: antinociceptive activity without cannabimimetic side effects

Ignatowska‐Jankowska, B M, Ghosh, S, Crowe, M S, Kinsey, S G, Niphakis, M J, Abdullah, R A, Tao, Q, O' Neal, S T +4 more·2014·British Journal of Pharmacology

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  11. Stimulatory effect of monoacylglycerol lipase inhibitor MJN110 on locomotion and step kinematics demonstrated by high-precision 3D motion capture in mice
    Bogna Marta Ignatowska-Jankowska, Ayşen Gürkan Özer, Alexander Kuck, Micah J. Niphakis, Daisuke Ogasawara, Benjamin F. Cravatt, Marylka Yoe Uusisaari · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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  13. Inhibitors of Endocannabinoids’ Enzymatic Degradation as a Potential Target of the Memory Disturbances in an Acute N-Methyl-D-Aspartate (NMDA) Receptor Hypofunction Model of Schizophrenia in Mice
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  14. Targeting the Endocannabinoid Metabolic Enzymes to Reduce Inflammatory Pain
    Sudeshna Ghosh · 2014 · VCU Scholars Compass (Virginia Commonwealth University)
  15. Analgesic and Anti-Inflammatory Effects of Monoacylglycerol Lipase Inhibition in Mice Subjected to Collagen-Induced Arthritis
    Sara R. Nass · 2015
  16. Cannabinoids: clearing the smoke on pain, inflammation and neurodegeneration
    Eric J. Downer, David P. Finn · 2014 · British Journal of Pharmacology
  17. Discriminative Stimulus Properties of Endogenous Cannabinoid Degradative Enzyme Inhibitors
    Owens, Robert · 2016 · VCU Scholars Compass (Virginia Commonwealth University)
  18. Development and Preclinical Evaulation of Novel Enzyme-targeting Radiotracers for Positron Emission Tomography
    Justin W. Hicks · 2015 · TSpace (University of Toronto)
  19. Endocannabinoid modulation of secretory and inflammatory causes of gastric pathology
    Molly S. Crowe · 2016
  20. Inhibiting the Cannabinoid Catabolic Enzyme MAGL to Potentiate the Anti-Arthritic Properties of the Synthetic Glucocorticoid Dexamethasone
    Sara R. Nass · 2017
  21. Resultados preclínicos de cannabinoides y dolor (algunos)
    Carlos Goicoechea García, Marina Sanz González, Miguel Ángel Martínez‐García, David Pascual Serrano, Eva Sánchez-Robles · 2022 · Revista de la Sociedad Española del Dolor
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  24. Role of the type-1 cannabinoid receptor in the control of water intake
    Zhe Zhao · 2019 · theses.fr (ABES)
  25. Fatty acid amide hydrolase (FAAH) and the endocannabinoid system in obesity: Mechanistic insights and pharmacological opportunities beyond incretin‐based therapies
    Ilaria Serra, Elisa Bisconti, Daniele Vergara, Anna Maria Giudetti, Francesco Vari · 2026 · British Journal of Pharmacology
  26. Advances in Small Molecule Research Targeting Monoacylglycerol Lipase in Drug Discovery
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  27. BindingDB Entry 50017870: Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives.
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  28. BindingDB Entry 50006784: Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders.
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  29. BindingDB Entry 50021641: Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization.
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  30. BindingDB Entry 50023447: Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.
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  31. BindingDB Entry 50000616: Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.
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  32. BindingDB Entry 50001937: Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.
    BindingDB · 2020 · UC San Diego