Cannabidiol is a negative allosteric modulator of the cannabinoid CB 1 receptor
Laprairie, R B, Bagher, A M, Kelly, M E M, Denovan‐Wright, E M·2015·British Journal of Pharmacology
Cited by (1,000)
Items 901–1,000 of 1,000
- Efficacy and Safety Profile of Cannabinoid-targeted Compounds for Seizure Control in Immature AnimalsMegan N. Huizenga · 2018 · DigitalGeorgetown (Georgetown University Library)
- Le cannabis, son Δ9-tétrahydrocannabinol/THC et le système endocannabinoïdeJean Costentin · 2020 · La Presse Médicale Formation
- Efectos del consumo de Omegas 6 y 3 sobre los niveles de ácido araquidónico y su asociación con la adicción a la comida en adultos obesos: Un estudio pilotoMorales Basto, Juan Pablo · 2020
- Circadian Medicine: Cannabinoid Chronotherapy for Treatment of HypertensionAidan Murray · 2020 · The Atrium (University of Guelph)
- CHARACTERIZATION AND TARGETING OF THE ENDOCANNABINOID SYSTEM IN TRAUMATIC BRAIN INJURYTallan Black · 2020 · HARVEST (University of Saskatchewan)
- Neuroprotective Effects of Cannabidiol Following Concussion: A Case StudyJyotpal Singh · 2019 · oURspace (University of Regina)
- Effects of Cannabis Abstinence on Symptoms and Cognition in Major Depressive DisorderAliya M. Lucatch · 2019 · TSpace (University of Toronto)
- 3-year Outcomes of Cannabis use Patterns: Evidence from a Longitudinal SurveyTongtong Chen · 2019 · TSpace (University of Toronto)
- Análise teórica da atuação de canabinoides nas vias metabólicas do câncer de mama por meio da biologia de sistemas e revisão sistemática da literaturaJONATAN TELLES RAMOS, Scheila De Avila E Silva, Vanessa Lins Lemos · 2021 · SaBios-Revista de Saúde e Biologia
- An Investigation into the Molecular Targets Mediating Cannabidiol Action in the Free-living Ciliate Tetrahymena pyriformisNathan Tims · 2021 · Lancaster EPrints (Lancaster University)
- Insights into the Molecular Role of Endocannabinoids in Diabetes Mellitus2021 · Biointerface Research in Applied Chemistry
- G protein-coupled receptor (GPCR)-dependent transductionHaley K. Andersen, Robert B. Laprairie · 2022 · Elsevier eBooks
- O efeito da exposição pré-natal ao Canabidiol na facilitação do Status Epilepticus pós-natalJórdan Fares Sampar · 2021
- NeuroscienceGodfrey D. Pearlson · 2020 · Elsevier eBooks
- Cannabidiol (CBD) drives sex-dependent impairments in omission, but has no effect on reinforcer devaluationCaroline Morehouse, C. Maddox, Rochelle K. van der Merwe, Robert McLaughlin, Jesse R. Scott, Marwan M. Ghanem, Eric S. Ramsson, Christopher D. Howard · 2022 · Behavioural Brain Research
- An insight into the acute effects of cannabidiol on human brain function and their relationship with the brain expression of its molecular targets: a neuroimaging meta-regression analysisBrandon Gunasekera, Cathy Davies, Grace Blest‐Hopley, Robin Paul Wilson, Geraldo F. Busatto, José Alexandre S. Crippa, Fábio Duran, Antônio Waldo Zuardi, Mattia Veronese, Joaquim Raduà et al. · 2022 · Research Square
- Molecular mechanisms underlying cannabis-induced risk of psychosisPaula Unzueta‐Larrinaga, Luis Felipe Callado, Leyre Urigüen · 2022 · Elsevier eBooks
- Canabidiol em modelo pré-clínico de dor neuropática: uma avaliação dos aspectos sensoriais, emocionais e inflamatórios relacionados com a modulação da sensibilidade dolorosaGleice Kelli Ribeiro da Silva Cardoso · 2022
- Application of cannabidol to ocular pharmacokinetics and pharmacodynamics.Alyssa S. Laun · 2022
- Cannabidiol for people with schizophreniaDiana Buitrago‐García, Guillermo Sánchez, Paula Alejandra Sánchez Correa, Stela del pilar Baracaldo, Santiago Felipe Gallego Gallego, Lone Baandrup · 2022 · Cochrane Database of Systematic Reviews
- Occupational Considerations Related to Cannabis UseGregory Lawson Smith · 2022 · Springer eBooks
- Phytocannabinoids and synthetic cannabinoids – pharmacotherapeutic aspectsNicoleta Mirela Blebea · 2023 · Farmacist ro
- Features of (+)-trans-cannabidiol-2-hydroxy pentyl and applications to disease: A focus on usage in diabetic nephropathyEduardo Muñóz, Matthias Winkler, Marcus Rudolf Götz, Isabel González‐Mariscal · 2023 · Elsevier eBooks
- Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRIThorsten Rudroff, Craig David Workman · 2023 · Elsevier eBooks
- Community Series - Purple Haze: Issues on Cannabis Legalization, volume II2023 · Frontiers research topics
- O uso de cannabis medicinal no tratamento de transtornos por uso de opioides: Uma revisão sistemáticaAugusto Mendes Ferreira, Jullyana Sarah Magalhães Silva, Kaio Figueiredo da Silva Cruz, Marycassiely Rodrigues Tizolim, Washington Luiz Aquino de Souza, Gabrielle Mendes Lima · 2023 · Research Society and Development
- Efectos terapéuticos del Cannabidiol en la epilepsia: un estudio preclínico en el modelo animal de epilepsia audiogénica GASH/SalGiselda Cabral-Pereira · 2023
- Effects of Cannabis Exposure on Adolescent Health and Development: A Narrative ReviewR. L. Li, Feng Tao · 2024 · Current Drug Research Reviews
- Medical Use of Cannabinoids and Psychedelic CompoundsAntonio Inserra, Danilo De Gregorio, Gabriella Gobbi · 2023 · Springer eBooks
- Cannabis use associated with lower mortality among hospitalized Covid-19 patients using the national inpatient sample: an epidemiological studyJoseph Igwe, Ugo Alaribe · 2024 · Journal of Cannabis Research
- Biological fate of cannabis and its metabolic productsRaja Babu, Abhipsa Mohapatra, Amarjeet Amarjeet, Debapriya Garabadu · 2024 · Elsevier eBooks
- Komplementärmedizinische Verfahren in der RheumatologieGernot Keyßer, Inna Frohne, Olaf Schultz, Monika A Reuss-Borst, Oliver Sander, Alexander Pfeil · 2024 · Zeitschrift für Rheumatologie
- Aplicabilidade da Cannabis e seus derivados no manejo da dor crônicaEmmanuel De Oliveira Carneiro, Bruna Rossi, Adriana Lopes de Freitas, Francisco José Germano Hennemann, Giovanna Rangel dos Santos, Hermes Castro de Araujo, Maraísa do Nascimento · 2024 · Revista Cereus
- Cannabis in anticancer drug developmentErnest Matambo, Andrew Glory Mtewa, Tadala Mzengo, Muhammad Riaz · 2024 · Elsevier eBooks
- In vivo and in vitro assays, and safety profiles of cannabinoidsMayeso N.V. Gwedela, Collins Edward Jana, Tuntufye Mwambyale, Ibrahim Chikowe, Lifa Chimphepo, George Chirambo · 2024 · Elsevier eBooks
- Cannabidiol enhances socially transmitted food preference: a role of acetylcholine in the mouse basal forebrainChih-Yu Chang, Wen Dai, Sherry Shu‐Jung Hu · 2024 · Psychopharmacology
- Medical Use of Cannabinoids and Psychedelic CompoundsAntonio Inserra, Danilo De Gregorio, Gabriella Gobbi · 2024 · Springer eBooks
- Principais alvos farmacológicos e potencial terapêutico do canabidiol (CDB)Ana Beatriz Monteiro de Medeiros, Laíza Andrade Soares Diniz, Aarão Gonçalves de Lira, Isabelle Teixeira Zambrzycki, Sara Calumbi Nachipindo Kawalende, Iara de Sousa Alves, Laura Oliveira Lorenzo de Andrade, Tiago Marinho Barbalho, Avanúzia Ferreira Matias, Edna da Silva Costa et al. · 2024 · Caderno Pedagógico
- Chronic Pain Management after Necrotizing Soft Tissue Infection (NSTI): A Case ReportKinyungu Njoroge, Vivian Matubia, Ngugi M. Kinyungu · 2024 · Case Reports in Clinical Medicine
- O USO DO CANABIDIOL NO TRATAMENTO DO TRANSTORNO OBSESSIVO COMPULSIVOLorena Alexia de Araujo, Marina da Lus, Ligia dos Santos Mendes Lemes Soares · 2024 · Revista Foco
- The Role of Cannabinoids and the Endocannabinoid System in the Treatment and Regulation of Nausea and VomitingErin M. Rock, Linda A. Parker · 2024 · Current topics in behavioral neurosciences
- Multiple casualty poisoning event in dogs after exposure to synthetic drugs of abuse in a public parkVasiliki Karadima, Poppy Sharpley, Andre Brenn, Shannon Ward, Nicola Bates · 2025 · Veterinary Record Case Reports
- Die Pharmakologie der CannabinoideGreg Copas, Erik de Almeida Amazonas, Sarah Brandon · 2024 · Springer eBooks
- Molecular mechanisms and pharmacology of cannabinoids: from theory to practiceMarek Lapka · 2025 · Klinická farmakologie a farmacie
- Cannabis sativa: A Review on Recent Patents and Advancements for Human HealthChanchal Rani, Nikita Kaushik, Prity Sharma, Chetna, Preeti Dahiya, Kaushal Arora, Etash Vashisht · 2025 · Current Bioactive Compounds
- Overview of the Endogenous Cannabinoid Signaling SystemTodd M. Stollenwerk, César E. Martinez Ramirez, Cecilia J. Hillard · 2025 · Springer eBooks
- Pharmacoepigenetics of cannabis and cannabinoidsAnna Starnawska, Lucas Holdgaard Ørskov, Qvist Per, Joca Sâmia · 2025 · Elsevier eBooks
- Geospatiotemporal and causal inferential epidemiological survey and exploration of cannabinoid- and substance-related carcinogenesis in USA 2003–2017Albert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
- Implications for policy2025 · Elsevier eBooks
- Sex differences in the capacity of minor phytocannabinoids to attenuate nociceptive insults in HIV-1 Tat-expressing miceAlaa N. Qrareya, Emaya M. Moss, Fakhri Mahdi, Mohammed Salahuddin, Duoyi Hu, Miguel A. De Leon, Amira S. Wanas, Mohamed M. Radwan, Mahmoud A. ElSohly, Nicole M. Ashpole et al. · 2025 · NeuroImmune Pharmacology and Therapeutics
- Identification of Tetrahydrocannabidiol Metabolites in Human UrineWilli Schirmer, Isabelle Mösch, Stefan Schürch, Wolfgang Weinmann · 2025 · Drug Testing and Analysis
- UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Complex Regional Pain SyndromeLilia Evans, Simon Erridge, Madhur Varadpande, Arushika Aggarwal, Isaac Cowley, Eleanor Clarke, Katy McLachlan, Ross Coomber, James Rucker, Michael W. Platt et al. · 2025 · Brain and Behavior
- Opposing Synovial Cannabinoid Receptor Type 2 and Transient Receptor Potential Vanilloid 1 Expression in Painful OsteoarthritisCollin A Toups, Lauren G Guillot, Kaitlyn Redondo, Sydney Jensen, Jennifer Klein, Luis Marrero · 2025 · Cureus
- Carvone derived cannabidiol enantiomers as novel anticonvulsantsRochelle M. Hines, April Contreras, Adriana Carrillo, Alexandra Paton, Antonio J. Tenorio, William A. Maio, Dustin J. Hines · 2025 · Neuropsychopharmacology
- In silico insights on the binding site and function of cannabinoids and cannabinoid acids on human 5-HT1A receptorBeow Keat Yap, Scott Palmer, Thomas Piccariello · 2025 · Journal of Molecular Graphics and Modelling
- The Pharmacological Profile of Plant-Derived Cannabinoids In VitroS P H Alexander · 2025 · Current topics in behavioral neurosciences
- Acute Effects of Cannabis and THC Oils on Cardiovascular Hemodynamics and Muscle Electrical Activity in Healthy Individuals: A Controlled Clinical Crossover Trial ProtocolMarina Lyra Lima Cabral Fagundes, Edna Karla Ferreira Laurentino, Bruno Lobão Soares, Matías Otto‐Yáñez, Emerson Arcoverde Nunes, Matheus de Freitas Fernandes‐Pedrosa, Jéssica Danielle Medeiros da Fonsêca, Vanessa Resqueti, Guilherme Fregonezi · 2025 · Journal of Clinical Medicine
- Cannabis sativa extracts reduce inclusion formation in a cell model of alpha-synuclein aggregationTamires de Almeida Cruz, Rodrigo de Paulo Osorio, Neide Mara de Menezes Epifânio, Madiha Mohieldin Merghani, Marcos Dias Pereira, Douglas Siqueira de Almeida Chaves, Tiago F. Outeiro, Cristiano Jorge Riger · 2025 · Fitoterapia
- Endocannabinoids in pain modulationVictoria Chapman, Stephen George Woodhams · 2025 · Handbook of behavioral neuroscience
- Cellular effects of endocannabinoids in the CNSKen Mackie, Beat Lutz · 2025 · Handbook of behavioral neuroscience
- Can Endocannabinoids Explain CBD-Mediated Reduction in Blood Pressure? Insights from a Randomized, Placebo-Controlled, Crossover TrialMarko Kumrić, Goran Dujić, Josip Vrdoljak, Daniela Šupe‐Domić, Željko Dujić, Joško Božić · 2025 · Cannabis and Cannabinoid Research
- The Pharmacokinetic and Pharmacodynamic Drug-drug Interaction Potential of CannabidiolGuillermo Alberto Keller, Jorge Alejandro Aimar · 2025 · Drug Metabolism and Bioanalysis
- Cannabidiol modulates classical and non-classical HLA expression in human choriocarcinoma cell lineKevin Martinez, María B. Palma, Fernando J. Sepúlveda, Edgardo Delfino Carosella, Marcela Nilda García, F.L. Riccillo · 2026 · Human Immunology
- FIGURES 45. Axinyssa djiferi spec. nov. 4 in A new species of Axinyssa Lendenfeld, 1897 (Porifera, Demospongiae, Halichondrida) from the Senegalese coastNicole Boury‐Esnault, Christian Marschal, Probst, Jean-Michel Korn-, Gilles Barnathan · 2002 · INFM-OAR (INFN Catania)
- Additional file 6 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- Additional file 3 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- Additional file 1 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- Additional file 4 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- Additional file 1 of Cannabis use associated with lower mortality among hospitalized Covid-19 patients using the national inpatient sample: an epidemiological studyJoseph Igwe, Ugo Alaribe · 2024 · Figshare
- Additional file 5 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- Additional file 1 of Cannabidiol (CBD) Use among children with juvenile idiopathic arthritisChristopher Failing, Boehnke, Kevin F., Meredith P. Riebschleger · 2021 · Figshare
- Additional file 2 of Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsAinhoa Bilbao, Spanagel, Rainer · 2022 · Figshare
- The Effect of Cannabidiol on Nociceptive Behaviour and the Endocannabinoid System in an Incisional Wound ModelMaria C. Redmond, Catherine R. Healy, Mary A. Hopkins, Rosmara Infantino, Georgina Gethin, Abhay S. Pandit, David P. Finn · 2025 · Pharmaceuticals
- Cannabidiol–Ion Channel Interactions Represent a Promising Preventive and Therapeutic Strategy in Hepatocellular CarcinomaMaría de Guadalupe Chávez-López, Arturo Ávalos‐Fuentes, Estrella del C. Cruz-Manzo, Pedro A. Aguirre-Arriaga, Benjamín Florán, Julio Isael Pérez‐Carreón, Cecilia Bañuelos, Javier Camacho · 2026 · Pathophysiology
- Vaping Δ 9 -tetrahydrocannabinol (Δ 9 -THC) in liquid forms: pharmacokinetics, pharmacodynamics, and regulatory implicationsBlock Aw, Danielle M. Smith, Maciej Lukasz Goniewicz · 2026 · Expert Review of Clinical Pharmacology
- Emerging Cannabidiol Research in Neurological Disorders: Insights into Epilepsy, Multiple Sclerosis, and DepressionJuwon kim · 2026 · International journal of high school research
- Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studiesGabriel P. A. Costa, Mayte A Cerezo-Matias, Melissa Christine Funaro, Deniz Bağdaş, Alfred P. Kaye, John Harrison Krystal, Ismene L. Petrakis, João Paulo De Aquino · 2026 · Molecular Psychiatry
- A single dose of cannabidiol increases ad libitum energy intake in healthy adults but does not affect postprandial glucose or lipid metabolismDrusus A. Johnson, Mark P. Funnell, Thomas G. Cable, Donald L. Peden, Chris J. McLeod, Patrick Crane Wheeler, Stephen J. Bailey, Tom Clifford, Liam M. Heaney, Lewis John James · 2026 · Appetite
- Cannabidiol Mitigates Ketamine-Induced Hyperlocomotion Via Allosteric Potentiation of Ventral Tegmental Glycine Receptor α1 SignalingXianglian Wang, Jing Xia, Heyi Luo, Huanhuan Mao, Dongyang Wang, Jin Jin, Wei Xiong · 2026 · Biological Psychiatry
- Radical Revelations: The Interplay of Nitrosative Stress, the Endocannabinoid System, and Treatment of Age-Related DisordersAvery Davis, Isabella Y. Casmedes, Michael D. Burton · 2026 · International Journal of Molecular Sciences
- Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidenceValentina F. Kitchigina, Liubov Shubina · 2026 · Neuroscience
- From Flower to Function: Medical Cannabis Modalities in Orthopedic PracticeChris Sun, Anthony Castro, Sina Ramtin · 2026 · SurgiColl
- Phase 2, open-label INSPIRE trial to assess the tolerability and effectiveness of transdermal cannabidiol gel in children and adolescents with 22q11.2 deletion syndrome (ZYN2-CL-031)Helen Heussler, Jonathan Cohen, Caroline B. Buchanan, David S. Albers, Kristen G Bzdek · 2026 · Journal of Neurodevelopmental Disorders
- Targeting Phantom Limb Pain with Cannabinoids in a Rat ModelAnjalika Eeswara, Kristin Perrucci, Stanislava Jergová, Jacqueline Sagen · 2026 · Medical Cannabis and Cannabinoids
- Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomesLuís Gustavo A. Patrone, Luciane H. Gargaglioni · 2026 · The Journal of Physiology
- Place preference in a female adolescent rat model of neuropathic pain: The effects of cannabidiol and oxycodone on cerebellum cell densityCrystal N. Li, Samantha Warren, Elaina Vlassopoulos, Marissa Sgro, Sydney Harris, Luke A. Henderson, Kevin A. Keay, Richelle Mychasiuk · 2026 · Psychopharmacology
- Etude des lipides membranaires comme facteur de vulnérabilité à la psychose chez des patients à ultra haut risque de psychose (UHR) et dans un modèle murinAriel Frajerman · 2021 · theses.fr (ABES)
- Evaluating the cannabinoid CB1 receptor as a therapeutic target in a Shank3 mouse model of autism and Phelan-McDermid syndromeFlavio Tomasi · 2023 · theses.fr (ABES)
- UK Medical Cannabis Registry: A Clinical Outcomes Analysis for MigraineLennon Hooper, Simon Erridge, Evonne Clarke, Katy McLachlan, Ross Coomber, Augustin Iqbal, James Rucker, Mark W. Weatherall, Mikael H Sodergren · 2026 · Brain and Behavior
- Cannabidiol and diabetic heart disease: Mechanistic evidence and translational challengesAfolake Arowolo, Oluyomi Stephen Adeyemı, Toluwalope Esther Ajonijebu, Aminu Musa, Hygon Mutavhatsindi, Rabia Johnson, Kenechukwu Obikeze · 2026 · Biomedicine & Pharmacotherapy
- Perinatal cannabidiol exposure reshapes astrocyte morphology and tripartite synapse organization in a sex-dependent mannerGabriel H Dias de Abreu, Jeremy Wilson, Vitor Ritzmann, Oscar John Moosbrugger, Clare T. Johnson, Ken Mackie, Heather B. Bradshaw, Jui-Yen Huang, Hui‐Chen Lu · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Cannabidiol at the crossroads: panacea, placebo, or problem?L. Cinnamon Bidwell, Ryan G. Vandrey · 2026 · Neuropsychopharmacology
- O uso de Canabidiol no tratamento da Doença de Alzheimer: Quais são os principais efeitos farmacológicos atribuídos ao Canabidiol relevantes para o tratamento da Doença de Alzheimer?Julia Grazielly dos Santos, Jean Colacite · 2026 · Research Society and Development
- Plasma cannabinoid pharmacokinetics following the inhalation of vaporised cannabis with and without cannabidiolDaniel Hall, Edward Chesney, Claire Mokrysz, Anna Caldwell, John M. Halket, Kat Petrilli, Matthew B. Wall, H. Valerie Curran, Tom P. Freeman, Will Lawn · 2026 · Drug and Alcohol Dependence
- Cannabinoids as a Systemic Modulator of Homeostasis: Modern Biochemical Mechanisms of Action and Clinical PerspectivesI. SORVILLO, A. S. VOITKIVSKA, M.-A. T. VACHKO, A. M. ZHELIZKO, Ю.М. Федевич · 2026 · Experimental and Clinical Physiology and Biochemistry
- Cannabinoids in autoimmune diseases: mechanistic insights and translational challengesYasir Akhtar Khan, Mohammad Anas, Farha Khan, Mubashshir Ali, Mohammed Mousa Al-Zharani, Fahd A. Nasr, Wajhul Qamar, Shakilur Rahman · 2026 · Biochemical Pharmacology
- Effects of THC, CBD, and Their Combination on EEG Dynamics in RatsMarcel Bochin, Čestmír Vejmola, Vlastimil Koudelka, Stanislav Jiříček, Marek Nikolič, Klára Šíchová, Tomáš Páleníček · 2026 · Physiological Research
- O USO DE CANABIDIOL NO TRATAMENTO DA EPILEPSIA IDIOPÁTICA CANINA: REVISÃO DE LITERATURACamille Nitolo Matias, Isabelle Tufano Leite · 2026 · Revista Foco
- Cannabidiol for Mucosal Diseases: Therapeutic Potential and Advanced Delivery StrategiesBo Han, Y Zhang, Y M Wang, Yue Shen, Jinping Niu, Shipo Li, Yuxi Li, Jingyu Wang, Xingyuan Ma, Wenyun Zheng · 2026 · Pharmaceutics
- Synthetic CB1 Modulators in Clinical Trials: A Medicinal Chemistry ReviewGustavo Manoel Oliveira dos Santos Naziozene, R Parise-Filho · 2026 · ChemMedChem