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The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Global prevalence of cerebral palsy: A systematic analysis

Open access
McIntyre, Sarah, Goldsmith, Shona, Webb, Annabel, Ehlinger, Virginie, Hollung, Sandra Julsen, McConnell, Karen, Arnaud, Catherine, Smithers‐Sheedy, Hayley, Oskoui, Maryam, Khandaker, Gulam, Himmelmann, Kate, the Global CP Prevalence Group*·2022·Developmental Medicine & Child Neurology

Abstract

Aim: To determine trends and current estimates in regional and global prevalence of cerebral palsy (CP). Method: A systematic analysis of data from participating CP registers/surveillance systems and population‐based prevalence studies (from birth year 1995) was performed. Quality and risk of bias were assessed for both data sources. Analyses were conducted for pre‐/perinatal, postnatal, neonatal, and overall CP. For each region, trends were statistically classified as increasing, decreasing, heterogeneous, or no change, and most recent prevalence estimates with 95% confidence intervals (CI) were calculated. Meta‐analyses were conducted to determine current birth prevalence estimates (from birth year 2010). Results: Forty‐one regions from 27 countries across five continents were represented. Pre‐/perinatal birth prevalence declined significantly across Europe and Australia (11 out of 14 regions), with no change in postneonatal CP. From the limited but increasing data available from regions in low‐ and middle‐income countries (LMICs), birth prevalence for pre‐/perinatal CP was as high as 3.4 per 1000 (95% CI 3.0–3.9) live births. Following meta‐analyses, birth prevalence for pre‐/perinatal CP in regions from high‐income countries (HICs) was 1.5 per 1000 (95% CI 1.4–1.6) live births, and 1.6 per 1000 (95% CI 1.5–1.7) live births when postneonatal CP was included. Interpretation: The birth prevalence estimate of CP in HICs declined to 1.6 per 1000 live births. Data available from LMICs indicated markedly higher birth prevalence. What this paper adds: • Birth prevalence of pre‐/perinatal cerebral palsy (CP) in high‐income countries (HICs) is decreasing. • Current overall CP birth prevalence for HICs is 1.6 per 1000 live births. • Trends in low‐ and middle‐income countries (LMICs) cannot currently be measured. • Current birth prevalence in LMICs is markedly higher than in HICs. • Active surveillance of CP helps to assess the impact of medical advancements and social/economic development. • Population‐based data on prevalence and trends of CP are critical to inform policy.

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Metadata

Authors
McIntyre, S., Goldsmith, S., Webb, A., Ehlinger, V., Hollung, S. J., McConnell, K., Arnaud, C., Smithers‐Sheedy, H., Oskoui, M., Khandaker, G., Himmelmann, K., & the Global CP Prevalence Group*
Venue
Developmental Medicine & Child Neurology
Publisher
Wiley
Published
2022-08-11
Volume
64
Issue
12
Pages
1494-1506
ISSN
  • 0012-1622 (ISSN-L)
  • 1469-8749
OpenAlex
W4291011402
Cited by
820
References
43
FWCI
82.77
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Global prevalence of cerebral palsy: A systematic analysis. https://app.cochat.ai/papers/10.1111/dmcn.15346
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McIntyre, S., Goldsmith, S., Webb, A., Ehlinger, V., Hollung, S. J., McConnell, K., Arnaud, C., Smithers‐Sheedy, H., Oskoui, M., Khandaker, G., Himmelmann, K., & the Global CP Prevalence Group*. (2022). Global prevalence of cerebral palsy: A systematic analysis. Developmental Medicine & Child Neurology. https://doi.org/10.1111/dmcn.15346

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