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The prevalence of diabetes‐specific emotional distress in people with Type 2 diabetes: a systematic review and meta‐analysis

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Perrin, N. E., Davies, M. J., Robertson, N., Snoek, F. J., Khunti, K.·2017·Diabetic Medicine

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Abstract

Aims: Psychological comorbidity, such as depression and/or diabetes‐specific emotional distress (diabetes distress), is widespread in people with Type 2 diabetes and is associated with poorer treatment outcomes. Although extensive research into the prevalence of depression has been conducted, the same attention has not been given to diabetes distress. The aim of this systematic review was to determine the overall prevalence of diabetes distress in people with Type 2 diabetes. Methods: Seven databases were searched to identify potentially relevant studies; eligible studies (adult population aged > 18 years with Type 2 diabetes and an outcome measure of diabetes distress) were selected and appraised independently by two reviewers. Multiple fixed‐ and random‐effects meta‐analyses were performed to synthesize the data; with primary analyses to determine the overall prevalence of diabetes distress in people with Type 2 diabetes, and secondary meta‐analyses and meta‐regression to explore the prevalence across different variables. Results: Fifty‐five studies ( n = 36 998) were included in the meta‐analysis and demonstrated an overall prevalence of 36% for diabetes distress in people with Type 2 diabetes. Prevalence of diabetes distress was significantly higher in samples with a higher prevalence of comorbid depressive symptoms and a female sample majority. Conclusions: Diabetes distress is a prominent issue in people with Type 2 diabetes that is associated with female gender and comorbid depressive symptoms. It is important to consider the relationship between diabetes distress and depression, and the significant overlap between conditions. Further work is needed to explore psychological comorbidity in Type 2 diabetes to better understand how best to identify and appropriately treat individuals.

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Authors: Perrin, N. E., Davies, M. J., Robertson, N., Snoek, F. J., & Khunti, K.
Affiliations: University of Leicester (GB)
Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Corresponding author: Perrin, N. E.
ORCID: Perrin, N. E.
Davies, M. J.
Robertson, N.
Snoek, F. J.
Khunti, K.
Venue: Diabetic Medicine
Publisher: Wiley
Published: 2017-08-31
Volume: 34
Issue: 11
Pages: 1508-1520
ISSN: 0742-3071 (ISSN-L)
1464-5491
DOI: 10.1111/dme.13448
OpenAlex: W2742497804
Cited by: 495
References: 54
Citations by year: 2026: 62 · 2025: 62 · 2024: 73 · 2023: 68 · 2022: 70 · 2021: 64 · 2020: 52 · 2019: 31 · 2018: 11 · 2017: 1
FWCI: 3.79
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Diabetic Medicine (publishedVersion)
PubMed (publishedVersion)
Pure Amsterdam UMC (submittedVersion, other-oa)
Data Archiving and Networked Services (DANS) (submittedVersion)
Figshare (submittedVersion, cc-by)
Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion)
Funders: University Hospitals of Leicester NHS Trust
National Institute for Health and Care Research
University of Leicester
Loughborough University
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords: diabetes distress, type 2 diabetes, prevalence, depression, psychological comorbidity, depressive symptoms, sex differences, female gender
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Depression, Diabetes Mellitus, Type 2, Humans, Middle Aged, Stress, Psychological, Prevalence, Young Adult

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The prevalence of diabetes‐specific emotional distress in people with Type 2 diabetes: a systematic review and meta‐analysis

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