Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial

Guzman, Cristina B.; Dulude, Helene; Piché, Claude; Rufiange, Marianne; Sadoune, Aziz A.; Rampakakis, Emmanouil; Carballo, Dolores; Triest, Myriam; Zhang, Michelle Xiaotian; Zhang, Shuyu; Tafreshi, Maryam; Sicard, Eric

doi:10.1111/dom.13134

Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial

Aims Nasal glucagon (NG) is a nasally‐administered glucagon powder, absorbed through the nasal mucosa, designed for treatment of severe hypoglycaemia. This study evaluated the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of NG in otherwise healthy participants with common colds and aft…