Epidemiology of bleeding symptoms and hypermobile Ehlers‐Danlos syndrome in paediatrics
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Hickey reported 7/13 (54%) of a case series of younger patients (9-18 years old) with hEDS per Villefranche criteria with menorrhagia post menarche.
“Hickey reported 7/13 (54%) of a case series of younger patients (9–18 years old) with hEDS per Villefranche criteria with menorrhagia post menarche.”
From Pediatric joint hypermobility: a diagnostic framework and narrative review (2023) · cites this paper as [69]
The study reports patients with hEDS diagnosed using Villefranche criteria and says menstrual bleeding symptoms contributed to elevated bleeding scores (study text; page unavailable). But our copy does not report menorrhagia in 7 of 13 post-menarche patients, and its stated eligibility range is 9–21 years, not 9–18. (LLM, conf=0.82)
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Cites
Beighton Score: A Valid Measure for Generalized Hypermobility in Children
Smits-Engelsman, B., Klerks, M., & Kirby, A. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.07.021 · Cited by 389 · see citing works
Jansson, A., Saartok, T., Werner, S., & Renström, P. (2004) · Acta Paediatrica · doi:10.1111/j.1651-2227.2004.tb02749.x · Cited by 195 · see citing works
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Research works printed but not linked: 8
- [1]Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ. Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK). Am J Med Genet 1998; 77: 31– 7. 9557891
- [2]Anstey A, Mayne K, Winter M, Van de Pette J, Pope FM. Platelet and coagulation studies in Ehlers-Danlos syndrome. Br J Dermatol 1991; 125: 155– 63. 1911298
- [3]Bowman M, Riddel J, Rand ML, Tosetto A, Silva M, James PD. Evaluation of the diagnostic utility for von Willebrand disease of a pediatric bleeding questionnaire. J Thromb Haemost 2009; 7: 1418– 21. 19496919
- [5]Tosetto A, Rodeghiero F, Castaman G A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). J Thromb Haemost 2006; 4: 766– 73. 16634745
- [6]Robertson JD, Yenson PR, Rand ML Expanded phenotype-genotype correlations in a pediatric population with type 1 von Willebrand disease. J Thromb Haemost 2011; 9: 1752– 60. 21711445
- [8]Mast KJ, Nunes ME, Ruymann FB, Kerlin BA. Desmopressin responsiveness in children with Ehlers-Danlos syndrome associated bleeding symptoms. Br J Haematol 2009; 144: 230– 3. 19036109
- [9]Jackson SC, Odiaman L, Card RT, van der Bom JG, Poon MC. Suspected collagen disorders in the bleeding disorder clinic: a case-control study. Haemophilia 2013; 246– 50. 23030528
- [10]O’Brien SH. Bleeding scores: are they really useful? Hematology Am Soc Hematol Educ Program 2012; 2012: 152– 6. 23233574
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Pediatric joint hypermobility: a diagnostic framework and narrative review
Tofts, L. J., Simmonds, J., Schwartz, S. B., Richheimer, R. M., O’Connor, C., Elias, E., Engelbert, R., Cleary, K., Tinkle, B. T., Kline, A. D., et al. (2023) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-023-02717-2 · Cited by 74 · see citing works
- Authors
- Hickey, S. E., Varga, E. A., & Kerlin, B.
- Affiliations
- Nationwide Children's Hospital (US)
- Corresponding author
- Hickey, S. E.
- Venue
- Haemophilia
- Publisher
- Wiley
- Published
- 2016-08-26
- Volume
- 22
- Issue
- 5
- Pages
- e490-3
- ISSN
- 1351-8216 (ISSN-L)
- 1365-2516
- PMC
- PMC6556229
- OpenAlex
- W2510717535
- Cited by
- 15
- References
- 2
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 1
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Haemophilia (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Center for Advancing Translational Sciences (UL1TR001070)
- Topics
- Health Sciences › Medicine › Hematology › Hemophilia Treatment and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Medicine › Hematology › Platelet Disorders and Treatments
- Keywords
- hypermobile Ehlers-Danlos syndrome, bleeding manifestations, pediatric patients, epidemiology, bleeding complications, connective tissue diseases
- MeSH terms
- Adolescent, Child, Ehlers-Danlos Syndrome, Female, Hemorrhage, Humans, Male, Surveys and Questionnaires, Cohort Studies
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