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Dutasteride and Enzalutamide Synergistically Suppress Prostate Tumor Cell Proliferation

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Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

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Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function

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Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

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Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell

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Overview of Pivotal Studies for Prostate Cancer Risk Reduction, Past and Present

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Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors

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Activity of Dutasteride Plus Ketoconazole in Castration-Refractory Prostate Cancer After Progression on Ketoconazole Alone

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Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer

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Effect of Small Molecules Modulating Androgen Receptor (SARMs) in Human Prostate Cancer Models

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Low systemic testosterone levels induce androgen maintenance in benign rat prostate tissue

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Subcellular localization of the five members of the human steroid 5α-reductase family

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Self-organizing molecular field analysis on pregnane derivatives as human steroidal 5α-reductase inhibitors

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New insights in equine steroidogenesis: an in-depth look at steroid signaling in the placenta

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5αDH‐DOC (5α‐dihydro‐deoxycorticosterone) activates androgen receptor in castration‐resistant prostate cancer

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Targeting Androgen Receptor Action for Prostate Cancer Treatment: Does the Post-Receptor Level Provide Novel Opportunities?

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Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models

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Levofloxacin exerts broad-spectrum anticancer activity via regulation of THBS1, LAPTM5, SRD5A3, MFAP5 and P4HA1

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Biology and natural history of prostate cancer and the role of chemoprevention

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Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro

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Therapeutic prospects of sex hormone receptor signaling in hormone-responsive cancers

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Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1

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Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

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A voting approach to identify a small number of highly predictive genes using multiple classifiers

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Effect of Saw Palmetto Supplements on Androgen‐Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth

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Novel 4-azaandrostenes as prostate cancer cell growth inhibitors: Synthesis, antiproliferative effects, and molecular docking studies

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In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum and Pore-Minimizing Active Ingredients

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Role of dutasteride in pre‐clinical ETS fusion‐positive prostate cancer models

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Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules

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Organotins as inhibitors targeting human and rat steroid 5α-reductase 1: structure-activity relationship and docking analysis

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Androgens modulate gene expression and specific DNA methylation pattern of steroid 5α-reductases in the frog Silurana tropicalis

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Pathophysiologie und Therapie der benignen Prostata-Hyperplasie

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Hormonal therapy for prostate cancer: Current topics and future perspectives

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Identification of Novel Gene Signature Associated with Cell Glycolysis to Predict Survival in Hepatocellular Carcinoma Patients

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Sequential transformation of 4-androstenedione into dihydrotestosterone in prostate carcinoma (DU-145) cells indicates that 4-androstenedione and not testosterone is the substrate of 5α-reductase

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Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists

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Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2

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Circulating and intraprostatic sex steroid hormonal profiles in relation to male pattern baldness and chest hair density among men diagnosed with localized prostate cancers

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Current Status of 5α-Reductase Inhibitors in Prostate Disease Management

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Molecular Profiles of Finasteride Effects on Prostate Carcinogenesis

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The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids

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Hormonal and Genetic Etiology of Male Androgenetic Alopecia

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Key players in progesterone and testosterone action: the metabolizing enzymes

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Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5α‐Reductase

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In silico and functional studies reveal novel loss-of-function variants of SRD5A2, but no variants explaining excess 5α-reductase activity

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N-glycoproteomic and proteomic alterations in SRD5A3-deficient fibroblasts

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Women with acute intermittent porphyria have a defect in 5α‐steroid production during the menstrual cycle

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Expression inEscherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases

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Emerging Proteins in CRPC: Functional Roles and Clinical Implications

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The Effect of Finasteride and Dutasteride on the Growth of WPE1-NA22 Prostate Cancer Xenografts in Nude Mice

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Medical Hypothesis: Loss of the Endocrine Function of the Prostate Is Important to the Pathophysiology of Postprostatectomy Erectile Dysfunction

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Osteoblasts Generate Testosterone From DHEA and Activate Androgen Signaling in Prostate Cancer Cells

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Prostate diseases – role of sex steroids and their inhibitors

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Current Understanding of Androgen Signaling in Prostatitis and its Treatment: A Review

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Genetic disorders of dolichol synthesis and utilization

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