The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Postoperative emesis following otoplasty in children.
Open accessAbstract
Sixty unpremedicated children aged between 3 and 14 years, scheduled for otoplasty, were randomly divided into one of three groups to receive either ondansetron 0.1 mg.kg-1, droperidol 75 micrograms.kg-1, or placebo at induction of anaesthesia. All patients received a standard general anaesthetic using thiopentone, atracurium and halothane. Opioid analgesia was avoided intra-operatively and infiltration with local anaesthetic was used prior to the start of surgery. Children who received ondansetron were less likely to vomit (15%) than those who received either droperidol (40%) or placebo (60%) (p < 0.01). This group also tolerated oral ingestion of fluids and solids earlier than those who received either droperidol or placebo (p < 0.001). There was no difference between the placebo or droperidol group in the incidence of vomiting or time to ingestion of oral fluids and meals. Three patients in the ondansetron group had a self-terminating nodal rhythm which was not associated with any haemodynamic disturbances. Postoperatively there were no untoward incidents in any of the groups and all patients were discharged home the day after surgery.
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Citations
Cites
Pediatric anesthesia morbidity and mortality in the perioperative period
Cohen, M. M., Cameron, C. B., & Duncan, P. G. (1995) · Journal of Clinical Anesthesia · doi:10.1016/0952-8180(95)94739-k · Cited by 365
Pediatric Anesthesia Morbidity and Mortality in the Perioperative Period
Cohen, M. M., Cameron, C. B., & Duncan, P. G. (1990) · Anesthesia & Analgesia · doi:10.1213/00000539-199002000-00005 · Cited by 343
Anesthetic Complications following Pediatric Ambulatory Surgery: A 3-yr Study
Patel, R. I., & Hannallah, R. S. (1988) · Anesthesiology · doi:10.1097/00000542-198812000-00044 · Cited by 176
Postoperative Vomiting in Children
Rowley, M. P., & Brown, T. C. K. (1982) · Anaesthesia and Intensive Care · doi:10.1177/0310057x8201000402 · Cited by 162
Mechanisms for Cardiac Dysrhythmias during Anesthesia
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The Antiemetic Effect of Droperidol Following Outpatient Strabismus Surgery in Children
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Du Pen, S., Scuderi, P., Wetchler, B. V., Sung, Y.-F., Mingus, M., Clayborn, L., Leslie, J. B., Talke, P. O., Apfelbaum, J. L., & Sharifi-Azad, S. (1992) · PubMed · Cited by 48
Research works printed but not linked: 2
- McKenzie R, 1991, Ondansetron, a selective serotonin type 3 (5‐HT3) antagonist, reduces nausea and vomiting in females following gynaecology surgery, Anesthesia and Analgesia, 74, S202
- Conahan TJ, 1991, Cardiovascular stability with rapid infusion of ondansetron, Anesthesia and Analgesia, 74, S52
Cited by
Tramer, M. R., Reynolds, D. J. M., Moore, R. A., & McQuay, H. J. (1997) · Anesthesiology · doi:10.1097/00000542-199712000-00004 · Cited by 435
Drugs for preventing postoperative nausea and vomiting
Carlisle, J., & Stevenson, C. A. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004125.pub2 · Cited by 264
RetractedHenzi, I., Sonderegger, J., & Tramèr, M. R. (2000) · Canadian Journal of Anesthesia/Journal canadien d'anesthésie · doi:10.1007/bf03018945 · Cited by 253
Drugs for preventing postoperative nausea and vomiting
Carlisle, J., & Stevenson, C. A. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004125.pub3 · Cited by 244
RetractedDomino, K. B., Anderson, E. A., Polissar, N. L., & Posner, K. L. (1999) · Anesthesia & Analgesia · doi:10.1213/00000539-199906000-00032 · Cited by 221
Metadata
- Authors
- Paxton, D., Taylor, R. H., Gallagher, T. M., & Crean, P. M.
- Affiliations
- Royal Belfast Hospital for Sick Children (GB)
- Venue
- Anaesthesia
- Publisher
- Wiley
- Published
- 1995-12
- Volume
- 50
- Issue
- 12
- Pages
- 1083-1085
- ISSN
- 0003-2409 (ISSN-L)
- 1365-2044
- OpenAlex
- W1999816166
- Cited by
- 51
- References
- 20
- Citations by year
- 2026: 1 · 2022: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 1
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Anaesthesia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hospital for Sick Children
- Topics
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Keywords
- otoplasty, postoperative vomiting, ondansetron, droperidol, antiemetic prophylaxis, children, general anesthesia, postoperative nausea and vomiting, early oral feeding, atracurium, halothane, thiopental
- MeSH terms
- Adolescent, Anesthesia, General, Antiemetics, Child, Child, Preschool, Drinking, Droperidol, Ear, External, Eating, Female, Humans, Male, Postoperative Complications, Postoperative Period, Vomiting, Ondansetron
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- Paxton, D., Taylor, R. H., Gallagher, T. M., & Crean, P. M. (1995). Postoperative emesis following otoplasty in children. Anaesthesia. https://doi.org/10.1111/j.1365-2044.1995.tb05957.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
