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The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Delirium is associated with early postoperative cognitive dysfunction

Open access
Rudolph, J. L., Marcantonio, E. R., Culley, D. J., Silverstein, J. H., Rasmussen, L. S., Crosby, G. J., Inouye, S. K.·2008·Anaesthesia

Abstract

Summary: The purpose of this analysis was to determine if postoperative delirium was associated with early postoperative cognitive dysfunction (at 7 days) and long‐term postoperative cognitive dysfunction (at 3 months). The International Study of Postoperative Cognitive Dysfunction recruited 1218 subjects ≥ 60 years old undergoing elective, non‐cardiac surgery. Postoperatively, subjects were evaluated for delirium using the criteria of the Diagnostic and Statistical Manual. Subjects underwent neuropsychological testing pre‐operatively and postoperatively at 7 days ( n = 1018) and 3 months ( n = 946). Postoperative cognitive dysfunction was defined as a composite Z ‐score > 2 across tests or at least two individual test Z ‐scores > 2. Subjects with delirium were significantly less likely to participate in postoperative testing. Delirium was associated with an increased incidence of early postoperative cognitive dysfunction (adjusted risk ratio 1.6, 95% CI 1.1–2.1), but not long‐term postoperative cognitive dysfunction (adjusted risk ratio 1.3, 95% CI 0.6–2.4). Delirium was associated with early postoperative cognitive dysfunction, but the relationship of delirium to long‐term postoperative cognitive dysfunction remains unclear.

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Metadata

Authors
Rudolph, J. L., Marcantonio, E. R., Culley, D. J., Silverstein, J. H., Rasmussen, L. S., Crosby, G. J., & Inouye, S. K.
Venue
Anaesthesia
Publisher
Wiley
Published
2008-08-06
Volume
63
Issue
9
Pages
941-947
ISSN
  • 0003-2409 (ISSN-L)
  • 1365-2044
OpenAlex
W2159817876
Cited by
183
References
2
FWCI
6.70
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Delirium is associated with early postoperative cognitive dysfunction. https://app.cochat.ai/papers/10.1111/j.1365-2044.2008.05523.x
The paper
Rudolph, J. L., Marcantonio, E. R., Culley, D. J., Silverstein, J. H., Rasmussen, L. S., Crosby, G. J., & Inouye, S. K. (2008). Delirium is associated with early postoperative cognitive dysfunction. Anaesthesia. https://doi.org/10.1111/j.1365-2044.2008.05523.x

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