The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Pharmacological approaches to methamphetamine dependence: a focused review
Open accessAbstract
Methamphetamine dependence is a serious worldwide public health problem with major medical, psychiatric, socioeconomic and legal consequences. Various neuronal mechanisms implicated in methamphetamine dependence have suggested several pharmacological approaches. A literature search from a range of electronic databases (PubMed, EMBASE, PsycInfo, the NIDA research monograph index and the reference list of clinicaltrials.gov) was conducted for the period from January 1985 to October 2009. There were no restrictions on the identification or inclusion of studies in terms of publication status, language and design type. A variety of medications have failed to show efficacy in clinical trials, including a dopamine partial agonist (aripiprazole), GABAergic agents (gabapentin) and serotonergic agents (SSRI, ondansetron, mirtazapine). Three double‐blind placebo‐controlled trials using modafinil, bupropion and naltrexone have shown positive results in reducing amphetamine or methamphetamine use. Two studies employing agonist replacement medications, one with d‐amphetamine and the other with methylphenidate, have also shown promise. Despite the lack of success in most studies to date, increasing efforts are being made to develop medications for the treatment of methamphetamine dependence and several promising agents are targets of further research.
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In the citing paper
“however, research on the efficacy of pharmacotherapies to date has produced inconsistent results.22”
From Protocol for a systematic review of psychological treatment for methamphetamine use: An analysis of methamphetamine use and mental health symptom outcomes (2017) · cites this paper as [22]
In the citing paper
“A number of agents that modulate functional output of DA systems are effective first-line treatments for substance-use disorders [177].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [177]
Citations
Cites
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Research works printed but not linked: 4
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Cited by
Sorted by citations
Courtney, K. E., & Ray, L. A. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.08.003 · Cited by 502
“…dependence identified only three ouble-blind placebo-controlled trials that have shown positive esults for reducing use of the substance (Karila et al., 2010). he first two trials found treatment effects within a specific ubpopulation of users; namely buproprion was associated…”
BackgroundInfluentialDichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299
“first-line treatments for substance-use disorders [177].”
Diez-Gutiérrez, L., Vicente, L. S., Barrón, L. J. R., Villarán, M. C., & Chávarri, M. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103669 · Cited by 277
Coppola, M., & Mondola, R. (2012) · Toxicology Letters · doi:10.1016/j.toxlet.2012.03.009 · Cited by 239
Mirtazapine to Reduce Methamphetamine Use: A Randomized Controlled Trial
Colfax, G. N. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.124 · Cited by 175
Metadata
- Authors
- Karila, L., Weinstein, A., Aubin, H., Benyamina, A., Reynaud, M., & Batki, S. L.
- Affiliations
- Inserm (FR)
- Hadassah Medical Center (IL)
- San Francisco VA Medical Center (US)
- Corresponding author
- Karila, Laurent
- Venue
- British Journal of Clinical Pharmacology
- Publisher
- Wiley
- Published
- 2010-05-10
- Volume
- 69
- Issue
- 6
- Pages
- 578-592
- ISSN
- 0306-5251 (ISSN-L)
- 1365-2125
- PMC
- PMC2883750
- OpenAlex
- W1747110054
- Cited by
- 242
- References
- 135
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 9 · 2023: 12 · 2022: 16 · 2021: 15 · 2020: 8 · 2019: 13 · 2018: 20 · 2017: 15 · 2016: 18 · 2015: 12 · 2014: 16 · 2013: 18 · 2012: 29
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal of Clinical Pharmacology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Drug Abuse (U10DA015815, R01DA016764, UG1DA015815)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- methamphetamine dependence, pharmacotherapy, partial dopamine agonist, aripiprazole, GABAergic agents, gabapentin, serotonergic agents, modafinil, bupropion, naltrexone, d-amphetamine, methylphenidate, drug addiction
- MeSH terms
- Animals, Calcium Channel Blockers, Humans, Immunotherapy, Methamphetamine, Narcotic Antagonists, Antipsychotic Agents, Neurotransmitter Agents, Amphetamine-Related Disorders, Rats
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