The DOI matches its Crossref record.
EPIDEMIOLOGY OF ACROMEGALY IN THE NEWCASTLE REGION
Abstract
Summary: In an attempt to derive estimates of the incidence and prevalence of acromegaly a survey of the population in the area served by the former Newcastle Regional Hospital Board has been conducted to detect cases of acromegaly alive after 1 January 1960 and diagnosed before 31 December 1971. Cases were detected by means of letters to general practitioners, hospital physicians, neurosurgeons and to hospital records officers, as well as from death certificates. From the population of 3.1 millions a firm diagnosis of acromegaly was made in 164 patients, in eighty‐one on clinical grounds alone and in eighty‐three with confirmation by assay of human growth hormone (hGH). The annual incidence of acromegaly appears to be close to three cases per million and the prevalence of diagnosed cases up to forty cases per million. In male acromegalics there was a significant increase in the risk of death from cardiovascular, cerebrovascular, respiratory and malignant diseases but in females from cerebrovascular disease only.
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Citations
Cited by
Premature mortality due to cardiovascular disease in hypopituitarism
Rosén, T., & Bengtsson, B.-Å. (1990) · The Lancet · doi:10.1016/0140-6736(90)91812-o · Cited by 1,402
Human growth hormone and human aging
CORPAS, E., HARMAN, S. M., & BLACKMAN, M. R. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-1-20 · Cited by 911
Mortality in Patients with Pituitary Disease
Sherlock, M., Ayuk, J., Tomlinson, J. W., Toogood, A. A., Aragon-Alonso, A., Sheppard, M. C., Bates, A. S., & Stewart, P. M. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0033 · Cited by 392
Outcome of transphenoidal surgery for acromegaly and its relationship to surgical experience
Ahmed, Elsheikh, Stratton, Page, Adams, & Wass (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00760.x · Cited by 291
Resmini, E., Minuto, F., Colao, A., & Ferone, D. (2009) · Acta Diabetologica · doi:10.1007/s00592-009-0112-9 · Cited by 147
Chidiac, R. M., & Aron, D. C. (1997) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70242-5 · Cited by 140
Hypogonadism in patients with acromegaly: data from the multi‐centre acromegaly registry pilot study
Katznelson, L., Kleinberg, D., Vance, M. L., Stravou, S., Pulaski, K. J., Schoenfeld, D. A., Hayden, D. L., Wright, M. E., Woodburn, C. J., & Klibanski, A. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01214.x · Cited by 95
Metadata
- Authors
- ALEXANDER, L., APPLETON, D., HALL, R., ROSS, W. M., & WILKINSON, R.
- Venue
- Clinical Endocrinology
- Publisher
- Wiley
- Published
- 1980-01
- Volume
- 12
- Issue
- 1
- Pages
- 71-79
- ISSN
- 0300-0664 (ISSN-L)
- 1365-2265
- OpenAlex
- W2088040716
- Cited by
- 466
- References
- 0
- FWCI
- 2.63
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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