Differential effect of immune cells on non‐pathogenic Gram‐negative bacteria‐induced nuclear factor‐κB activation and pro‐inflammatory gene expression in intestinal epithelial cells

Haller, D.; Holt, L.; Parlesak, A.; Zanga, J.; Bäuerlein, A.; Sartor, R. B.; Jobin, C.

doi:10.1111/j.1365-2567.2004.01874.x

Differential effect of immune cells on non‐pathogenic Gram‐negative bacteria‐induced nuclear factor‐κB activation and pro‐inflammatory gene expression in intestinal epithelial cells

Summary We have previously shown that non‐pathogenic Gram negative bacteria induce RelA phosphorylation, nuclear factor (NF)‐κB transcriptional activity and pro‐inflammatory gene expression in intestinal epithelial cells (IEC) in vivo and in vitro . In this study, we investigated the molecular me…