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Silver nanoparticles: the powerful nanoweapon against multidrug-resistant bacteria: Activity of silver nanoparticles against MDR bacteria
Abstract
In the present scenario, pharmaceutical and biomedical sectors are facing the challenges of continuous increase in the multidrug-resistant (MDR) human pathogenic microbes. Re-emergence of MDR microbes is facilitated by drug and/or antibiotic resistance, which is acquired way of microbes for their survival and multiplication in uncomfortable environments. MDR bacterial infections lead to significant increase in mortality, morbidity and cost of prolonged treatments. Therefore, development, modification or searching the antimicrobial compounds having bactericidal potential against MDR bacteria is a priority area of research. Silver in the form of various compounds and bhasmas have been used in Ayurveda to treat several bacterial infections since time immemorial. As several pathogenic bacteria are developing antibiotic resistance, silver nanoparticles are the new hope to treat them. This review discusses the bactericidal potential of silver nanoparticles against the MDR bacteria. This multiactional nanoweapon can be used for the treatment and prevention of drug-resistant microbes.
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Cited by
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Durán, N., Durán, M., de Jesus, M. B., Seabra, A. B., Fávaro, W. J., & Nakazato, G. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.11.016 · Cited by 1,542
Similarities and Differences between Silver Ions and Silver in Nanoforms as Antibacterial Agents
Kędziora, A., Speruda, M., Krzyżewska, E., Rybka, J., Łukowiak, A., & Bugla-Płoskońska, G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020444 · Cited by 452
Rónavári, A., Igaz, N., Adamecz, D. I., Szerencsés, B., Molnar, C., Kónya, Z., Pfeiffer, I., & Kiricsi, M. (2021) · Molecules · doi:10.3390/molecules26040844 · Cited by 361
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Metadata
- Authors
- Rai, M. K., Deshmukh, S. D., Ingle, A. P., & Gade, A. K.
- Venue
- Journal of Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-03-28
- Volume
- 112
- Issue
- 5
- Pages
- 841-852
- ISSN
- 1364-5072 (ISSN-L)
- OpenAlex
- W2139221049
- Cited by
- 1,524
- References
- 0
- FWCI
- 23.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Rai, M. K., Deshmukh, S. D., Ingle, A. P., & Gade, A. K. (2012). Silver nanoparticles: the powerful nanoweapon against multidrug-resistant bacteria: Activity of silver nanoparticles against MDR bacteria. Journal of Applied Microbiology. https://doi.org/10.1111/j.1365-2672.2012.05253.x
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