The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Antibiotics in periodontal therapy: advantages and disadvantages*
Abstract
Abstract. Antibiotic treatment of periodontitis aims at eradicating or controlling specific pathogens. Prime candidates for antibiotic therapy are patients with recently diagnosed active periodontitis or a history of recurrent disease who fail to stabilize following mechanical/surgical therapy. Since a variety of microbes with differing antimicrobial susceptibility profiles may cause periodontitis, selection of antimicrobial agents should be based on proper microbial diagnosis and sensitivity testing, as well as consideration of the patient's medical status. The risk of treating chemotherapeutically solely on the basis of clinical features, radiographic findings or a limited microbiological analysis, is failure to control the pathogens or overgrowth of new pathogens. A review of published papers reveals that appropriate systemic antibiotic therapy may enhance healing in patients with recent or high risk of periodontal breakdown. Systemic antibiotic therapy seems more predictable than topical administration in eradicating periodontal pathogens from deep periodontal pockets. Several promising antimicrobial agents for periodontitis treatment need testing in placebo‐controlled, double‐blind, randomized clinical trials.
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Citations
Cites
The microbiota associated with successful or failing osseointegrated titanium implants
Mombelli, A., van Oosten, M. A. C., Schürch, E., & Lang, N. P. (1987) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1987.tb00298.x · Cited by 2,054
Slots, J., & Genco, R. J. (1984) · Journal of Dental Research · doi:10.1177/00220345840630031101 · Cited by 939
Self-citationDzink, J. L., Socransky, S. S., & Haffajee, A. D. (1988) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01590.x · Cited by 715
Slots, J., & Listgarten, M. A. (1988) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb00999.x · Cited by 708
Self-citationSlots, J., Reynolds, H. S., & Genco, R. J. (1980) · Infection and Immunity · doi:10.1128/iai.29.3.1013-1020.1980 · Cited by 648
Self-citationListgarten, M. A. (1986) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1986.tb01485.x · Cited by 486
Gram negative species associated with active destructive periodontal lesions
Dzink, J. L., Tanner, A. C. R., Haffajee, A. D., & Socransky, S. S. (1985) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1985.tb00936.x · Cited by 471
Bacterial Profiles of Subgingival Plaques in Periodontitis
Loesche, W. J., Syed, S. A., Schmidt, E., & Morrison, E. C. (1985) · Journal of Periodontology · doi:10.1902/jop.1985.56.8.447 · Cited by 433
Listgarten, M. A., Lindhe, J., & Hellden, L. (1978) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1978.tb01918.x · Cited by 412
The Bacteriology of Acute Necrotizing Ulcerative Gingivitis
Loesche, W. J., Syed, S. A., Laughon, B. E., & Stoll, J. (1982) · Journal of Periodontology · doi:10.1902/jop.1982.53.4.223 · Cited by 365
Cited by
Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance
Speer, B. S., Shoemaker, N. B., & Salyers, A. A. (1992) · Clinical Microbiology Reviews · doi:10.1128/cmr.5.4.387 · Cited by 517
Sharma, S., Khan, I. A., Ali, I., Ali, F., Kumar, M., Kumar, A., Johri, R. K., Abdullah, S. T., Bani, S., Pandey, A., et al. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00045-08 · Cited by 131
Metadata
- Authors
- Slots, J., & Rams, T. E.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 1990-08
- Volume
- 17
- Issue
- s1
- Pages
- 479-493
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2091794394
- Cited by
- 396
- References
- 64
- FWCI
- 23.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Slots, J., & Rams, T. E. (1990). Antibiotics in periodontal therapy: advantages and disadvantages*. Journal of Clinical Periodontology. https://doi.org/10.1111/j.1365-2710.1992.tb01220.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
