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Use of snus and risk for cardiovascular disease: results from the Swedish Twin Registry

Hansson, J., Pedersen, N. L., Galanti, M. R., Andersson, T., Ahlbom, A., Hallqvist, J., Magnusson, C.·2009·Journal of Internal Medicine
DOI 10.1111/j.1365-2796.2009.02081.x
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Abstract

Abstract.: Objective. To study the association between snus use and the risk for cardiovascular disease, i.e. ischemic heart disease and stroke. Design. Cohort study. Setting. Sweden. Subjects. Sixteen thousand six hundred and forty‐two male Swedish twins participating in the Screening Across the Lifespan Twin Study, conducted in 1998–2002, were followed for incident cardiovascular disease. Participants were without a history of cardiovascular disease at baseline and incident cases were identified via the Swedish Cause of Death Register and Hospital Discharge Register. Results. Overall, there was no association between use of snus and risk for cardiovascular disease. Current snus users, without a smoking history, had a relative risk of 1.00 (95% confidence interval 0.69–1.46) for cardiovascular disease as compared to non users. Corresponding relative risks for ischemic heart disease and stroke were 0.85 (95% confidence interval 0.51–1.41) and 1.18 (95% confidence interval 0.67–2.08), respectively. In smoking adjusted models, risk estimates for ischemic heart disease in relation to snus use were all close to unity regardless of timing or intensity of snus use. However, current heavy snus users (consuming more than four cans week−1) had a relative risk for stroke of 1.75 (95% confidence interval 0.95–3.21). Conclusion. These data do not support any strong association between snus use and risk for cardiovascular disease.

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  • Among male twins, there is no association between using snus and risk for cardiovascular disease (RR = 1.00; 95% CI: 0.69-1.46), lower risk for ischemic heart disease (RR = 0.85; 95% CI: 0.51-1.41), and increased risk for stroke (RR = 1.18; 95% CI: 0.67-2.08) compared to never-users.

    “no association between using snus and risk for cardiovascular disease (risk ratio (RR) = 1.00; 95% CI: 0.69-1.46)and lower risk for ischemic heart disease (IHD) (RR = 0.85; 95% CI: 0.51-1.41)compared to never-users.However, there was an increased risk for stroke (RR = 1.18; 95% CI: 0.67-2.08)among snus users compared to never-users (Hansson et al. 2009).”

    From Comparison of the Health Effects Associated with the Use of Snus and Tobacco-Free Oral Nicotine Pouches: A Systematic Review (2026) · cites this paper as Hansson et al. 2009

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Research works printed but not linked: 26

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Authors
Hansson, J., Pedersen, N. L., Galanti, M. R., Andersson, T., Ahlbom, A., Hallqvist, J., & Magnusson, C.
Venue
Journal of Internal Medicine
Publisher
Wiley
Published
2009-05-07
Volume
265
Issue
6
Pages
717-724
ISSN
  • 0954-6820
  • 1365-2796
DOI
10.1111/j.1365-2796.2009.02081.x
Cited by
42
References
0
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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